Presenting a Model of Self-sacrificial behaviors of Leaders in Organizations; Interpretive Structural Modeling (ISM) Method by Amir Hossein Abdallahzadeh, Seyyed Mohammad Moghimi, Hossein Imani

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Association of per- and polyfluoroalkyl substances with gout risk: a cross-sectional analysis of NHANES 2007–2018 data emphasizing mixture effects by Haixin Feng, Siran Li, Shiqing Huang, Linxi He, Ruihao Huang, Renhuizi Wei, Xin Peng, Haiyi Yan, Chongxiang Xiong, Bingsong Zhang

“…PFHxS has the longest metabolic half-life in humans (7.3 years) and bioaccumulates in the endocrine, immune, nervous, and reproductive systems. …”
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Removal of Tetracycline Using Tungsten Disulfide/Graphene Oxide as Photocatalyst: Effect of Light Irradiation and Kinetic Studies by Zulhatiqah Zolekafeli, Syafarina Farisa Sateria, Ahmad Husaini Mohamed, Siti Hajar Alias, Kavirajaa Pandian Sambasevam, Siti Nor Atika Baharin

“…Once widely utilised in both human and veterinary medicine, tetracycline antibiotics are now recognised as major environmental pollutants with detrimental effects on the environment and human health. …”
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Assessment of MPOX infection-related knowledge levels, concerns, and associated factors: a community-based cross-sectional study by Mehmet Emin Arayici, Suleyman Dolu, Hasan Ozdek Sayilir, Hatice Simsek, Sükran Kose

“…Abstract Background MPOX (Monkeypox) is a zoonotic disease of increasing global concern due to its re-emergence and potential for human-to-human transmission. Effective public health interventions rely on understanding socio-demographic determinants of knowledge and perceptions of the disease. …”
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La création franco-chinoise dans sa matérialité. Le symbolisme dans l’œuvre plastique de Xuefeng Chen et son rapport à la matière by Guillaume Thouroude

“…In doing so, it juxtaposes Xuefeng’s art with the philosophical thought of Gaston Bachelard, particularly his essays on the impact of fire, water and air on the human psyche. The article focuses on the symbolic dimension inherent in each material manipulated by the artist. …”
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INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses by Jason Ho, Chelsie Macedo, Garrett Cyprus, Rajay Pandit, Anya Polovina, Nadja Kern, Abrahim Hussain, Sae Jeong Ahn, William Crago, Emily Rowell, Florian J Sulzmaier, John C Timmer, Brendan P Eckelman

“…Preclinical safety, as well as pharmacodynamic (PD) and PK profiling was carried out in non-human primates.Results INBRX-120 effectively expanded and enhanced the cytotoxic capacity of CD8 T cells and natural killer cells towards tumor cells without affecting regulatory T cells in vitro and in vivo. …”
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Individual mobility prediction by considering current traveling features and historical activity chain by Xiaotong Zhang, Zhipeng Gui, Yuhang Liu, Dehua Peng, Qianxi Lan, Zhangxiao Shen, Huan Chen, Yuhui Zuo, Yao Yao, Huayi Wu, Kai Li, Kun Qin

“…Whereas, it remains challenging due to the complexity and uncertainty of human mobility. Existing methods mainly consider spatiotemporal contexts in current traveling, but overlook those in historical trips, as well as relationships between traversed road intersections. …”
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Multicentre study conducted across centres in the USA, Europe and Australia to assess the safety and effectiveness of a bilateral hypoglossal nerve stimulation system for the treat... by B Tucker Woodson, Maria V Suurna, M Boyd Gillespie, Tod C Huntley, Melyssa Hancock, Angela Santos, Jeyakumar Subbaroyan, Fatima Makori, Grégoire Fesneau, Clemens Heiser, David T Kent

“…Vincent’s Hospital Melbourne Human Research Ethics Committee, Ethisch Comite Universitair Ziekenhuis Antwerpen and Technische Universitat Munchen reviewed and approved this protocol. …”
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Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci by Natasha Berthold, Silvana Gaudieri, Sean Hood, Monika Tschochner, Allison L. Miller, Jennifer Jordan, Laura M. Thornton, Cynthia M. Bulik, Patrick Anthony Akkari, Martin A. Kennedy

“…To test our hypothesis, we curated a list of 20 prioritised variants in non-coding regions, poorly represented in the current human reference genome but that may have functional consequences in AN pathology. …”
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Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke by Naoki Yamada, Ryo Ueda, Wataru Kakuda, Ryo Momosaki, Takahiro Kondo, Takuya Hada, Nobuyuki Sasaki, Takatoshi Hara, Atsushi Senoo, Masahiro Abo

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Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

“…The M6P-conjugated antibody against a protein of interest (POI) efficiently internalized targeted soluble proteins, such as human tumor necrosis factor (TNF), in both cancer cell lines and human immune cells, through the endo-lysosomal pathway as demonstrated by confocal microscopy and flow cytometry. …”
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Research Note: Establishment of vector system harboring duck RNA polymerase I promoter for avian influenza virus by Yunyueng Jang, Yoon-Gi Baek, Yu-Na Lee, Ra Mi Cha, Yun-Chan Choi, Min-Ji Park, Youn-Jeong Lee, Eun-Kyoung Lee

“…Reverse genetics (RG) systems are extensively utilized to investigate the characteristics of influenza viruses and develop vaccines, predominantly relying on human RNA polymerase I (pol I). However, the efficiency of RG systems for avian-origin influenza viruses may be compromised due to potential species-specific interactions of RNA pol I. …”
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Taenia solium taeniosis and cysticercosis literature in Tanzania provides research evidence justification for control: A systematic scoping review. by Helena Aminiel Ngowi, Andrea Sylvia Winkler, Uffe Christian Braae, Robinson Hammerthon Mdegela, Ernatus Martin Mkupasi, Mwemezi Lutakyawa Kabululu, Faustin Peter Lekule, Maria Vang Johansen

“…Prevalence of taeniosis of 2.3% - 5.2% was estimated based on copro-antigen ELISA while human cysticercosis of >16% was estimated based on serum antigen ELISA (Ag-ELISA) or IgG Western Blot. …”
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Health and Environmental Impact of Hospital Wastes: Systematic Review by Hela Ghali, Asma Ben Cheikh, Sana Bhiri, Lamia Bouzgarrou, Mohamed Ben Rejeb, Imed Gargouri, Houyem Said Latiri

“…Therefore, the specific management of healthcare waste is a major concern due to the potentially high risks for human health and the environment.…”
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A novel platform for engineered AAV-based vaccines by Sabrina Babutzka, Miranda Gehrke, Anastasia Papadopoulou, Maria Diedrichs-Möhring, Maria Giannaki, Lena Hennis, Bastian Föhr, Cale Kooyman, Andreas Osterman, Evangelia Yannaki, Gerhild Wildner, Hermann Ammer, Stylianos Michalakis

“…In line with this, AAV.RBDs were neutralized by sera from human donors vaccinated against SARS-CoV-2. When administered subcutaneously to rabbits, AAV.RBDs elicited a strong humoral response against SARS-CoV-2 RBD. …”
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Conditioning factors for the scientific productivity of undergraduate students of health sciences at a private Peruvian University: A cross-sectional analytical study [version 3; p... by Oriana Rivera-Lozada, Isabel Cristina Rivera-Lozada, César Antonio Bonilla-Asalde

“…Results From the total of 400 students, 74.5% were male, 57.25% were aged between 18 and 27 years, 17% belonged to the school of human medicine and 72% were in their sixth year of studies. …”
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Safety of interleukin inhibitors in patients with plaque psoriasis and history of neoplasms: a multicenter retrospective study – IL PSO (Italian landscape psoriasis) by Mario Valenti, Luciano Ibba, Sara Di Giulio, Luigi Gargiulo, Piergiorgio Malagoli, Anna Balato, Carlo G. Carrera, Paolo Dapavo, Eugenia V. Di Brizzi, Valentina Dini, Francesca Gaiani, Francesco Loconsole, Angelo V. Marzano, Matteo Megna, Alessandra Michelucci, Luca Potestio, Simone Ribero, Antonio Costanzo, Alessandra Narcisi

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Substantia nigra alterations in mice modeling Parkinson’s disease by I. N. Rozhkova, S. V. Okotrub, E. Yu. Brusentsev, T. A. Rakhmanova, D. A. Lebedeva, V. S. Kozeneva, N. A. Shavshaeva, N. V. Khotskin, S. Ya. Amstislavsky

“…Taken together, the results obtained in our work qualify the B6.Cg-Tg strain as a pertinent model for studying the early stage of human PD already at the age of six months.…”
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Predicting conversion to psychosis using machine learning: response to Cannon by Jason Smucny, Tyrone D. Cannon, Tyrone D. Cannon, Carrie E. Bearden, Carrie E. Bearden, Jean Addington, Kristen S. Cadenhead, Barbara A. Cornblatt, Matcheri Keshavan, Daniel H. Mathalon, Diana O. Perkins, William Stone, Elaine F. Walker, Scott W. Woods, Scott W. Woods, Ian Davidson, Cameron S. Carter

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Experiencing the risk of overutilising opioids among patients with chronic non-cancer pain in ambulatory care (ERONA): the protocol of an exploratory, randomised controlled trial by Odette Wegwarth, Joerg J Meerpohl, Norbert Donner-Banzhoff, Claudia Spies, Christine Schmucker, Erika Schulte, Edris Nury, Dirk Brockmann, Stefan Wind, Eva Goebel, Wolf-Dieter Ludwig, Ralph Hertwig

“…The study was developed by the authors and will be conducted by the market research institution IPSOS Health.Ethics and dissemination The study was approved by the Institutional Review Board of the Max Planck Institute for Human Development. Results will be disseminated through peer-reviewed journals, conference presentations and social media.Trial registration number DRKS00020358.…”
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