Correlation between Clinicopathology and Expression of Heat Shock Protein 72 and Glycoprotein 96 in Human Esophageal Squamous Cell Carcinoma by Xiaoping Wang, Qiaoxia Wang, Huanping Lin

“…We investigated the correlation between clinicopathology and expression of HSP72 and gp96 in human esophageal squamous cell carcinoma. The expression of HSP72 and gp96 was studied in 120 human esophageal squamous cell carcinomas with or without metastasis as well as in mucous membrane adjacent to cancers by way of immunohistochemistry. …”
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β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease by Bing Xu, Kang Xiao, Xiaoxi Jia, Rundong Cao, Donglin Liang, Ruhan A, Weiwei Zhang, Chunjie Li, Liping Gao, Cao Chen, Qi Shi, Xiaoping Dong

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Communication invitée du thèmeLes corps maladesWhy are health and sickness socially patterned across human societies? by Michelle Kelly-Irving

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Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings by Rushika Conroy, Gerardo Febres, Donald J. McMahon, Michael O. Thorner, Bruce D. Gaylinn, Irene Conwell, Louis Aronne, Judith Korner

“…Weight stable women after RYGB were randomized to receive placebo or recombinant human metreleptin (0.05 mg/kg twice daily). At weeks 0 and 16, a liquid meal challenge was performed. …”
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Transgression de l’espace et espace de la transgression dans The Human Stain de Philip Roth by Gilles Mayné

“…He is then disavowed and banned from the university community. Reading The Human Stain, one is forced to question what is generally considered as being evil and to become aware of the extreme difficulty and yet unavoidable necessity to transgress the space of the supposed common good which locks the notions up within themselves to freeze conscious thinking and behavior.…”
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CHARACTERISTIC CHANGES IN THE COPY NUMBER OF INTERSPERSED REPEATS IN BONE MARROW CELLS OF MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS HUMAN DNA by E. V. Dolgova, A. V. Prokopenko, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. V. Panov, S. N. Zagrebelnyi, M. A. Shurdov

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Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix by Xiaodong Feng, Marcia G. Tonnesen, Shaker A. Mousa, Richard A. F. Clark

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Living wounds (anfechtungen) or blacksmithing of the human soul? The pastoral art of marvellous exchange (mirifica commutatio) in spiritual well-being by D.J. Louw

“… Many of the unexpected, undeserved forms of suffering and the constant exposure to human brokenness infiltrate schemata of interpretation and frameworks of meaninggiving, causing guilt, doubt, torment, and anguish – a kind of paralysis of the human soul; the hopelessness of désespoir (the nausea of unhope). …”
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Linking the life stages of fish into a habitat-ecological flow assessment scheme under climate change and human activities by Yiming Zhang, Wensheng Wang, Siyi Yu

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HUBUNGAN INFEKSI HUMAN PAPILOMA VIRUS TERHADAP TERJADINYA KETUBAN PECAH DINI DI RSIA SITI HAWA PADANG by Fiona Dewanti, Andani Eka Putra, Bobby Indra Utama

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Structural organization of the cranial vault in Neanderthals and present-day humans: Can endocranial shape characteristics be explained by vault thickness? by Sélim Natahi, Simon Neubauer, Zewdi J. Tsegai, Jean-Jacques Hublin, Philipp Gunz

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Fabrication of a Porous Metal-Organic Framework with Polar Channels for 5-Fu Delivery and Inhibiting Human Osteosarcoma Cells by Li-Chun Zhao, Mei Tang, Qian-Hua Zhang, Zhi-Yi Hu, Hong-Wei Gao, Xia-Yun Liao, Gang Wang, Jing Leng

“…Furthermore, as indicated by the MTT assay, this drug/MOF composite shows low toxicity toward the human normal cells and demonstrates obvious anticancer activity against the human osteosarcoma cell line MG63.…”
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Developing human upper, lower, and deep lung airway models: Combining different scaffolds and developing complex co-cultures by Rasika S Murkar, Cornelia Wiese-Rischke, Tobias Weigel, Sascha Kopp, Heike Walles

“…Advanced in vitro models are crucial for studying human airway biology. Our objective was the development and optimization of 3D in vitro models representing diverse airway regions, including deep lung alveolar region. …”
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Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail by Lorena V. Cortés-Medina, Herminia Pasantes-Morales, Alejandro Aguilera-Castrejon, Arturo Picones, Cesar O. Lara-Figueroa, Enoch Luis, Juan Jose Montesinos, Victor A. Cortés-Morales, M. P. De la Rosa Ruiz, Erika Hernández-Estévez, Laura C. Bonifaz, Marco Antonio Alvarez-Perez, Gerardo Ramos-Mandujano

“…Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders. …”
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Human activity recognition: an approach 2D CNN-LSTM to sequential image representation and processing of inertial sensor data by Wallace Camacho Carlos, Alessandro Copetti, Luciano Bertini, Leonard Barreto Moreira, Otávio de Souza Martins Gomes

“…The field of human activity recognition, abbreviated as HAR, benefits significantly from deep learning by addressing the complexity of human behavior and the vast volume of data produced by sensors. …”
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Human Genomic Loci Important in Common Infectious Diseases: Role of High-Throughput Sequencing and Genome-Wide Association Studies by Gerald Mboowa, Ivan Sserwadda, Marion Amujal, Norah Namatovu

“…Application of genome sequencing technologies and genomics has enabled us to interrogate the host-pathogen interface for improving human health. Human populations are constantly locked in evolutionary arms races with pathogens; therefore, identification of common infectious disease-associated genomic variants/markers is important in therapeutic, vaccine development, and screening susceptible individuals in a population. …”
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Stratification system with dual human endogenous retroviruses for predicting immunotherapy efficacy in metastatic clear-cell renal cell carcinoma by Li Xu, Stephane Oudard, Catherine Sautes-Fridman, Xiaoping Su, Gabriel G. Malouf, Virginie Verkarre, Salma Kotti, Fangrong Yan, Yann-Alexandre Vano, Wolf Herve Fridman, Cheng-Ming Sun, Xiaofan Lu, Wenxuan Cheng

“…Background Endogenous retrovirus (ERV) elements are genomic footprints of ancestral retroviral infections within the human genome. While the dysregulation of ERV transcription has been linked to immune cell infiltration in various cancers, its relationship with immune checkpoint inhibitor (ICI) response in solid tumors, particularly metastatic clear-cell renal cell carcinoma (ccRCC), remains inadequately explored.Methods This study analyzed patients with metastatic ccRCC from two prospective clinical trials, encompassing 181 patients receiving nivolumab in the CheckMate trials (−009 to –010 and −025) and 48 patients treated with the ipilimumab-nivolumab combination in the BIONIKK trial. …”
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Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation by Wen Zeng, Hanjun Dai, Ming Yan, Xiaojun Cai, Hong Luo, Min Ke, Zeming Liu

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The human pressure on the middle Vistula River wildlife: the number and distribution of people and their activity on the river during the breeding season of birds by Dariusz Bukaciński, Monika Bukacińska, Ewelina Mastalerz

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Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines by Wilfredo Hernández, Juan Paz, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Jorge Manzur, Lothar Hennig, Joachim Sieler, Steffen Blaurock, Lothar Beyer

“…The in vitro cytotoxic activity measurements indicate that the palladium(II) complexes (IC50=0.01–9.87 μM) exhibited higher antiproliferative activity than their free ligands (IC50=23.48–70.86 and >250 μM) against different types of human tumor cell lines. Among all the studied palladium(II) complexes, the [Pd(TSC3)2] (8) complex exhibited high antitumor activity on the DU145 prostate carcinoma and K562 chronic myelogenous leukemia cells, with low values of the inhibitory concentration (0.01 and 0.02 μM, resp.).…”
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