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28021
Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats
Published 2025-01-01“…To elucidate the mechanism of action among conventional and current novel types of SCSs, a stable and reliable electrophysiology model in the consensus animals to mimic human SCS treatment is essential. We have recently developed a new in vivo implantable pulsed-ultrahigh-frequency (pUHF) SCS platform for conducting behavioral and electrophysiological studies in rats. …”
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28022
Critical Success Factor Proyek TI: Studi Kasus Mobile Government
Published 2023-04-01“…The results of this study indicate that planning is the most prioritized factor, followed by human resource competence. While the last rank is knowledge management. …”
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28023
Determining the status of ecosystem degradation trends and their implications for ecological integrity in the southern African grassland biome
Published 2025-04-01“…We recorded eleven prominent land cover use classes dominated by agricultural activities accounting for 31.9 % (365,629 km2) of which 27.4 % was cultivated area, and 4.5 % was forest plantation, and human settlement covered 4.2 %. Of the 1332 alien plant species recorded, 17.8 %-36.2 % were invasive. …”
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28024
Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis Through HGF/YAP Signaling Pathway
Published 2024-11-01“…Methods The culture media from bone-metastatic LUAD cell A549-GFP-LUC-BM3 (BM3-CM) and A549-GFP-LUC (A549-CM) were separately applied to human umbilical vein endothelial cell (HUVEC). A colony formation assay, scratch assay, and tube formation assay were conducted to evaluate the proliferation, migration, and angiogenesis of HUVEC. …”
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28025
Absent in melanoma 2: a potent suppressor of retinal pigment epithelial-mesenchymal transition and experimental proliferative vitreoretinopathy
Published 2025-01-01“…Transcriptome analysis using RNA-sequencing (RNA-Seq) revealed that AIM2 was significantly downregulated in primary human RPE (phRPE) cells undergoing EMT and proliferation. …”
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28026
Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit...
Published 2024-11-01“…The iPSC lines ICGi052-A and ICGi052-B proliferate stably, form colonies with a morphology characteristic of human pluripotent cells, have a normal diploid karyotype (46,XX), express endogenous alkaline phosphatase and pluripotency markers (OCT4, NANOG, SSEA-4 and TRA-1-60) and are able to differentiate into derivatives of three germ layers: ento-, ecto- and mesoderm. …”
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28027
Comparative Study of Angiotensin Convertase Enzyme (ACE2) Gene Expression in Patients with Covid-19 By Molecular Method
Published 2024-12-01“…This particular virus spreads rapidly likely because of the Spike proteins affinity, to the human ACE2 cell receptor causing harm to organs, like the lungs in type 2 pneumocytes that abundantly express this receptor. …”
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28028
Biodegradation of CAHs and BTEX in groundwater at a multi-polluted pesticide site undergoing natural attenuation: Insights from identifying key bioindicators using machine learning...
Published 2025-02-01“…These contaminants pose serious risks to ecosystems and human health. Natural attenuation (NA) has emerged as a sustainable solution, with microorganisms playing a crucial role in pollutant biodegradation. …”
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28029
Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay
Published 2024-12-01“…To circumvent the challenges of cell-based assays, SARS-CoV-2 surrogate virus neutralization tests (sVNTs) measure inhibition of the binding of the spike (S) protein receptor binding domain (RBD) to its receptor, human angiotensin-converting enzyme 2 (hACE2) by neutralizing antibodies. …”
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28030
A new epidemic wave of Bordetella pertussis in paediatric population: impact and role of co-infections in pertussis disease
Published 2025-01-01“…Rhinovirus, Metapneumovirus and Parainfluenza-virus were the most prevalent in our pediatric population. Co-infections of human bocavirus with B.pertussis were observed exclusively in patients with respiratory failure. …”
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28031
Summer Research Internship Curriculum to Promote Self-Efficacy, Researcher Identity, and Peer-to-Peer Learning: Retrospective Cohort Study
Published 2025-02-01“…ObjectiveThis retrospective pre-then-post study aimed to evaluate changes in self-reported ratings of research abilities among a cohort of undergraduate students who participated in a summer research program. MethodsThe Human BioMolecular Atlas Program (HuBMAP) piloted the implementation of a web-based academic enrichment curriculum for the Summer 2023 Research Internship cohort, which was comprised of students from groups underrepresented in biomedical artificial intelligence research. …”
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28032
Audit Sistem Informasi pada Sistem Manajemen Layanan Satu Atap (SIMANTAP) Menggunakan Kerangka COBIT 5.0 (Studi Kasus: Bank Indonesia Provinsi Bengkulu)
Published 2022-10-01“…The role of information technology has supported banking business processes, both in the ownership of human resources as well as data and information. …”
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28033
Carotenoids in the treatment of age-related macular degeneration: a drug delivery system does matter
Published 2023-03-01“…Besides aging, there are other multiple heterogenic risk factors associated with AMD: gender, environmental condition, lifestyle, genetic characteristics, chronic inflammatory processes in the human body, level of education, etc. It is important for the ophthalmologist to be aware of modifiable risk factors and thus to collect a comprehensive medical history, interact with patients using motivational interviewing and to involve promptly other healthcare specialists into the patient management strategy. …”
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28034
Odyssey of environmental and microbial interventions in maize crop improvement
Published 2025-01-01“…Maize (Zea mays) is India’s third-largest grain crop, serving as a primary food source for at least 30% of the population and sustaining 900 million impoverished people globally. The growing human population has led to an increasing demand for maize grains. …”
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28035
Synthesizing evidence to guide the design and implementation of effective strategies for discontinuing postoperative antibiotic prophylaxis in surgical settings: an umbrella review...
Published 2025-01-01“…Methods This umbrella review searched for articles from PubMed/MEDLINE and Scopus, focusing on reviews conducted on human subjects on PAP to prevent SSIs, published in English language from 2019 to 5th July 2024. …”
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28036
Identification and validation of the important role of KIF11 in the development and progression of endometrial cancer
Published 2025-01-01“…Abstract Background Human kinesin family member 11 (KIF11) plays a vital role in regulating the cell cycle and is implicated in the tumorigenesis and progression of various cancers, but its role in endometrial cancer (EC) is still unclear. …”
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28037
“Equity” in genomic health policies: a review of policies in the international arena
Published 2024-12-01“…In addition, General and Specific Policy Repositories, Global Consortia in Genomic Medicine, WHO Collaborating Centers in Genomics, Australian Genomics, Public Policy Projects, Global Genomic Medicine Consortium (G2MC), G2MC conference Oct 2023 and National Human Genome Research Institute databases were searched using the inclusion and exclusion criteria. …”
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28038
Gender differences in use of cigarette and non-cigarette tobacco products among adolescents aged 13–15 years in 20 African countries
Published 2024-01-01“…Introduction Examining gender differences in youth tobacco use is important as it aligns tobacco control within the context of broader human development goals seeking to eliminate gender inequalities. …”
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28039
The immune landscape of fetal chorionic villous tissue in term placenta
Published 2025-01-01“…Recent studies have characterized the transcriptional profile of the first trimester (T1) placenta; however, the phenotypic and functional diversity of chorionic villous immune cells at term (T3) remain poorly understood.MethodsTo address this knowledge gap, immune cells from human chorionic villous tissues obtained from full-term, uncomplicated pregnancies were deeply phenotyped using a combination of flow cytometry, single-cell RNA sequencing (scRNA-seq, CITE-seq) and chromatin accessibility profiling (snATAC-seq).ResultsOur results indicate that, relative to the first trimester, the frequency of fetal macrophages (HBC, proliferating HBC) is significantly reduced, whereas that of infiltrating maternal monocytes/macrophages (PAMM1b, PAMM1a, PAMM2, MAC_1) increased in T3. …”
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28040
Characterization of adult T-cell leukemia/lymphoma patients with specific skin lesions in a tertiary dermatological service in Brazil
Published 2025-02-01“…IntroductionHuman T-lymphotropic virus type-1 (HTLV-1) is endemic in some countries, including Brazil. …”
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