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27541
Global perspectives on the biodegradation of LDPE in agricultural systems
Published 2025-01-01“…The increasing use of plastics globally has generated serious environmental and human health problems, particularly in the agricultural sector where low-density polyethylene (LDPE) and other plastics are widely used. …”
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27542
Prolyl 4‐hydroxylase α‐subunit family regulation of type I collagen deposition and IL17RB/c‐Jun activation synergistically mediate choline dehydrogenase promotion of colorectal can...
Published 2025-01-01“…The study explored the functional role and mechanism of CHDH in CRC metastasis using human CRC tissues and a xenograft mouse model. CHDH expression was significantly higher in CRC compared to normal tissues and showed a positively correlation with CRC tumor‐nodes‐metastasis stage. …”
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27543
Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli
Published 2024-12-01“…Therapeutic bioconjugates are emerging as an essential tool to combat human disease. Site-specific conjugation technologies are widely recognized as the optimal approach for producing homogeneous drug products. …”
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27544
The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Cont...
Published 2025-01-01“…Notably, PLANTOR does not contain procoagulant minerals or nanoparticles that could remain in the human body, and therefore does not belong to means with a chemical or biochemical mechanism of action. …”
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27545
A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation
Published 2025-01-01“…Mimicking the trauma milieu in a human ex vivo whole blood model, we found significant mCRP generation as well as NET formation, prevented by blocking pCRP conformational changes. …”
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27546
Network meta-analysis of cadmium toxicity against Chlorella vulgaris and the role of growth stimulants and macronutrients
Published 2024-10-01“…BACKGROUND AND OBJECTIVES: The presence of heavy metals, specifically cadmium, in the environment poses significant threats to both ecological systems and human health. However, microalgae have shown potential in addressing this issue through their ability to absorb cadmium and produce valuable biomass, making them a promising solution for bioremediation. …”
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27547
Comparison of radiation esophagitis associated with daytime versus evening radiotherapy in patients with esophageal carcinoma
Published 2025-01-01“…Abstract Purpose Based on the demonstration of a circadian rhythm in the human oral mucosa cell cycle, with most cells in the G2/M phase in the afternoon and at night, the present study evaluated the severity of acute radiation esophagitis and treatment outcomes in esophageal squamous cell carcinoma patients receiving radiotherapy (RT) in the daytime versus in the evening. …”
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27548
Systematic review: e-cigarettes vs. conventional cigarettes
Published 2025-02-01“…Years of research on larger sample sizes are needed to determine their impact on humans. …”
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27549
To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway
Published 2019-01-01“…Type 2 diabetes mellitus (T2DM) has become a chronic disease, serious harm to human health. Complications of the blood pipe are the main cause of disability and death in diabetic patients, including vascular lesions that directly affects the prognosis of patients with diabetes and survival. …”
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27550
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27551
Impacted lower third molar classification and difficulty index assessment: comparisons among dental students, general practitioners and deep learning model assistance
Published 2025-01-01“…Another set of radiographs was used to compare the accuracy between human experts and the top-performing CNN. This dataset was also given to DSs and GPs. …”
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27552
High-performance UWB Vivaldi antenna on FR4: A cost-effective solution for wearable technologies
Published 2025-03-01“…The antenna's suitability for wearable applications was validated through testing on flat and curved human phantoms made of skin, fat, and muscle, showing low Specific Absorption Rate (SAR) values across the UWB spectrum, confirming its safety for body-centric use. …”
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27553
Sistem Identifikasi Kesehatan Berdasarkan Detak Jantung, Kadar Oksigen, dan Suhu Tubuh Menggunakan Metode Fuzzy Mamdani
Published 2023-10-01“…Abstract Health is an important factor in human life. Therefore, in this paper we offer an effective and efficient approach in early detection of health. …”
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27554
Evaluating the Performance of Low-cost PM Sensors over Multiple COALESCE Network Sites
Published 2023-02-01“…Abstract Air quality is a global concern, with particulate matter receiving considerable attention due to its impact on human health and climate change. Recent advances in low-cost sensors allow their deployment in large number to measure spatio-temporal and real-time air quality data. …”
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27555
Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China.
Published 2020-12-01“…<h4>Background</h4>Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. We aimed to evaluate the associations of circulating sphingolipids with incident T2D and to explore underlying mechanisms.…”
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27556
Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma
Published 2018-01-01“…Pheochromocytomas (PCCs) show the highest degree of heritability in human neoplasms. However, despite the wide number of alterations until now reported in PCCs, it is likely that other susceptibility genes remain still unknown, especially for those PCCs not clearly syndromic. …”
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27557
An approach for accurate identification and monitoring of species in mangrove forests based on multi-source spectral data and deep learning
Published 2025-03-01“…Also, this minimizes the economic and human efforts and reduces risk of error, thus leading to more efficient and effective ecosystem conservation.…”
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27558
An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f...
Published 2025-02-01“…Secondary outcomes will include tooth survival, longevity of restoration, quality of life, perception and satisfaction of the participants’ parents/guardians.Ethics and dissemination This protocol has been approved by the Human Research Ethics Committee of Universidade Metropolitana de Santos (protocol number: 6.019.297. …”
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27559
From cellular senescence towards age-related macular degeneration: the role of telomeres
Published 2020-08-01“…Karpova<sup>2</sup></b> </p> <p> <b><sup>1</sup>Russian Medical Academy of Continuous Professional Education, Moscow, <br> Russian Federation</b> </p> <p> <b><sup>2</sup>Institute of General Pathology and Pathophysiology, Moscow, Russian Federatio</b>s </p> <p> <i>Since the discovery, telomeres and telomerase have been extensively studied, at first, as a mechanism of cellular senescence, and then, as human health and disease indicators. Telomeres that protect chromosomal ends play a vital role in genomic stability by preserving information.…”
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27560
TiO<sub>2</sub> Nanosphere/MoSe<sub>2</sub> Nanosheet-Based Heterojunction Gas Sensor for High-Sensitivity Sulfur Dioxide Detection
Published 2024-12-01“…With the growing severity of air pollution, monitoring harmful gases that pose risks to both human health and the ecological environment has become a focal point of research. …”
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