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27521
Freeze-Drying for the Reduction of Fruit and Vegetable Chain Losses: A Sustainable Solution to Produce Potential Health-Promoting Food Applications
Published 2025-01-01“…These analyses were performed together with an investigation of the correlations among phenolics and their antioxidant properties, and a bioinformatic approach was used to estimate the main potential bio-targets in human beings. Furthermore, a statistical approach using Principal Component Analysis (PCA) was carried out for a multivariate characterization of these products. …”
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27522
Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases
Published 2025-02-01“…The formation and structure of Cryptococcus granulomas are poorly understood due to inconsistent human pathology results and disagreement between necrotic granuloma-forming rat models and non-necrotic granuloma-forming mouse models. …”
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27523
Biodesulfurization of high-sulfur oil from the Karazhanbas field of Kazakhstan with deep eutectic solvents
Published 2025-01-01“…It is known that sulfur negatively affects the operational properties of petroleum products, causes the corrosion of pipelines, and adversely affects the environment and the human body. Therefore, the development of biodesulfurization technology, taking into account local features, is relevant for this field. …”
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27524
Distinct phenotypes of salivaricin-producing Ligilactobacillus salivarius isolated from the gastrointestinal tract of broiler chickens and laying hens
Published 2025-01-01“…Finally, the functional characterization of active salP allows for a better understanding of its potential to control specific bacteria in human food and animal production.…”
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27525
Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes
Published 2025-02-01“…The Web of Science, Embase, and PubMed databases were searched on January 2024 using specific exclusion criteria (e.g., study of non-human subjects, focus on skin diseases, or treatments) to identify relevant articles. …”
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27526
Time to act: Institutional mental health support for Ukrainian academic staff during wartime
Published 2025-01-01“…Natalia Tsybuliak is grateful to the Ukraine Research Network@ZOiS, funded by the German Federal Ministry of Education and Research, for support in implementing the research.This work was supported by the Ministry of Education and Science of Ukraine as part of the state-funded research project 0123U105351, “Ukrainian universities in new realities: the impact of war and mechanisms for preserving the scientific and human resource potential for training specialists in high-tech fields.”…”
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27527
Immuno-PET Imaging of Siglec-15 Using the Zirconium-89-Labeled Therapeutic Antibody, NC318
Published 2023-01-01“…In these preclinical studies, the therapeutic mAb, NC318 (antihuman/murine Siglec-15 mAb), was labeled with zirconium-89 and evaluated in human Siglec-15 expressing cancer cells and mouse xenografts for potential use as a clinical diagnostic imaging agent. …”
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27528
A Pooling Genome-Wide Association Study Identifies Susceptibility Loci and Signaling Pathways of Immune Thrombocytopenia in Chinese Han Population
Published 2020-01-01“…To extend the genetic evidence and to identify novel candidates of ITP, we performed a pooling genome-wide association study (GWAS) by IlluminaHumanOmniZhongHua-8 combining pathway analysis in 200 ITP cases and 200 controls from Chinese Han population (CHP). …”
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27529
Extraction, Chemical Composition and Antidiabetic Potential of Crude Polysaccharides from Centella asiatica (L.) Urban
Published 2024-05-01“…The global prevalence of diabetes mellitus (DM) is escalating, posing a significant challenge to human healthcare systems. In the present study, mineral and monosaccharide compositions, and antidiabetic potential of polysaccharide fractions separated from Centella asiatica (L.) leaves (CAL) were assessed. …”
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27530
Enhanced preoperative prediction of breast lesion pathology, prognostic biomarkers, and molecular subtypes using multiple models diffusion-weighted MR imaging
Published 2025-02-01“…Significant differences in IVIM-D, IVIM-D*, and DKI-MK values were observed between human epidermal growth factor receptor 2 (HER2)-negative and HER2-positive tumors. …”
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27531
Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects
Published 2025-02-01“…Platelet aggregation was analyzed using collagen-induced aggregation in human whole blood. Anticoagulant activities were evaluated by determining the effects on prothrombin time (PT) and activated partial thromboplastin time (aPTT). …”
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27532
Improving antibiotic utilization in West Africa: enhancing interventions through systematic review and evidence synthesis
Published 2025-02-01“…Despite western sub-Saharan Africa being identified as one of the major hotspots of antimicrobial resistance (AMR) with the highest mortality, a comprehensive regional analysis of the magnitude and key drivers of AMR due to human antibiotic use has not been conducted. Method We carried out a systematic review by conducting a comprehensive search in various databases including PubMed and Scopus for eligible articles published in the English Language between 1 January 2000 and 14 February 2024. …”
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27533
Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Su...
Published 2018-01-01“…All patients were enrolled in a first-in-human study (NCT01172964) of NSC-mediated therapy for recurrent high-grade glioma. …”
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27534
Effect of photobiomodulation as preventive treatment of diabetic foot ulcer: randomised, controlled, double-blind, clinical trial protocol
Published 2025-01-01“…Assessments will be performed at the beginning of the study, after 30 days (clinical examination) and after 60 days (clinical examination, assessment of peripheral neuropathy (PN) and peripheral artery disease (PAD), blood and urine examinations and quality of life).Ethics and dissemination This protocol received approval from the Human Research Ethics Committee of Nove de Julho University and the Mandaqui Hospital Complex (certificate number: 66098522.0.3001.5511; final approval date: 22 June 2023). …”
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27535
A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome
Published 2025-01-01“…A simple and rapid method to extract free sterols from human serum and quantitate their concentration using isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) without derivatization was developed. …”
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27536
Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion
Published 2025-01-01“…Overall, we introduced a sequencing method to assess provirus size in human peripheral blood and identified the widespread presence of monoclonal distribution of UIS in AIDS-ART group after long-term treatment. …”
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27537
Assembly of Genetically Engineered Ionizable Protein Nanocage-based Nanozymes for Intracellular Superoxide Scavenging
Published 2025-01-01“…Specifically, ionizable repeated Histidine-Histidine-Glutamic acid (9H2E) sequences are genetically incorporated into the outer surface of human heavy chain FTn, followed by the assembly of various chain-like nanostructures via a two-armed polyethylene glycol (PEG). …”
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27538
Dynamique forestière et pression urbaine dans le Parc national du Banco (Abidjan, Côte d’Ivoire)
Published 2013-10-01“…The study of the types of human pressures in PNB is conducted through observations to detect spatial changes in recent years. …”
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27539
Investigating BLS instructors’ ability to evaluate CPR performance: focus on compression depth, rate, and recoil
Published 2025-01-01“…Key metrics such as chest compression speed, depth, and recoil were examined to identify the degree of consistency between human and automated evaluations. Results In this study, CPR performance was analyzed using QCPR devices and BLS instructors across metrics like speed, depth, and recoil. …”
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27540