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27481
A disintegrin and metallopeptidase domain (ADAM) 12, ADAM 17 mRNA and ADAM10 protein hold potential as biomarkers for detection of early gastric cancer
Published 2025-01-01“…In the TCGA data analyses, EGC tissues (n = 57) expressed significantly higher mRNA levels of ADAM8, ADAM9, ADAM10, ADAM12, and ADAM17 than normal tissues (n = 35) (p < 0.005). In human blood sample analyses, ADAM12 (p = 0.0007), ADAM17 mRNA (p < 0.0001) and ADAM10 (p < 0.0017) protein were significantly elevated in patients with EGC (n = 27 for mRNA and n = 25 for protein) compared to the controls (n = 30 for mRNA and n = 26 for protein). …”
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27482
Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer
Published 2025-01-01“…Fatty acid is one of the main nutrients of human beings, which is closely related to diabetes, hypertension and other diseases. …”
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27483
The use of large language models in detecting Chinese ultrasound report errors
Published 2025-01-01“…This study demonstrates the potential of LLMs to enhance ultrasound report accuracy, outperforming human experts in certain aspects.…”
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27484
Performance of Banana Peelings Extract as A Natural Coagulant in the Treatment of Surface Water Case Study: River Rwizi, Mbarara.
Published 2023“…The existence of suspended solids and other pollutants in water leads to countless drawbacks during water treatment creating deleterious disinfection by-products such as trihalomethanes, Dichlorobromomethane and Trichloroacetic acid after the use of chemical coagulants, which are potentially deleterious to human health and the environment. However, many researchers have come up with different plant-based coagulants to replace Aluminum sulphate thus, the main objective of this research was to the investigate performance of banana peelings extract as a natural coagulant in the treatment of surface water by comparing the coagulation action of the raw and ripe banana peelings extracts against Aluminium sulphate, a chemical coagulant as the control experiment. …”
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27485
Impact of Sexual Harassment on Pupils Academic Performance in Selected Primary Schools of Kitumba Sub-County Kabale District.
Published 2024“…It happens around all societies and symbolizes a brutal violation of human rights most especially for the weaker sex. …”
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27486
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27487
Entrepreneurship skills application among ICT Graduates of Muni University, Uganda
Published 2022“…The results of the study identified that the key entrepreneurship skills acquired by Muni University ICT graduates are: innovativeness; business and economic management; human relations and interpersonal skills; and communication skills. …”
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27488
A phenomenological study of knowledge concealment in country water and sewage engineering company
Published 2024-08-01“…In the final results of the research, the main themes with the titles, human resource management, process system, knowledge concealment, and consequences were identified, and each main theme consists of several sub-themes as described in the text of the article. …”
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27489
IGJR issue 1/2018
Published 2017-06-01“… The IGJR publishes articles from the disciplines from the social sciences/humanities, reflecting the current state of research on intergenerational justice. …”
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27490
Targeted Delivery of BMS-1166 for Enhanced Breast Cancer Immunotherapy
Published 2025-01-01“…Drug encapsulation efficiency, loading degree, and release profile were examined by high-performance liquid chromatography. Human breast cancer MDA-MB-231 was used to test the cytotoxicity. …”
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27491
Preassembled complexes of hAgo2 and ssRNA delivered by nanoparticles: a novel silencing gene expression approach overcoming the absence of the canonical pathway of siRNA processing...
Published 2025-12-01“…In this study, we preassembled complexes with the human enzyme argonaute 2 (hAgo2) and a small interfering RNA (siRNA)/single-stranded RNA (ssRNA) against B. gibsoni and B. microti metabolite transporters. …”
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27492
Microscale bone interlocking enhances osseointegration strength on the rough surface of 3D-printed titanium implants: experimental and finite element analysis
Published 2025-02-01“…Over the past decade, immediately loaded 3D-printed titanium implants have demonstrated predictable clinical outcomes in human jaws, highlighting their superior osseointegration strength, which is attributed to their increased surface roughness. …”
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27493
The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights
Published 2025-01-01“…The gut microbiota plays a pivotal role in human metabolic health by influencing immune responses, digestion, and metabolic homeostasis. …”
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27494
Identification of Potential Vectors and Detection of Rift Valley Fever Virus in Mosquitoes Collected Before and During the 2022 Outbreak in Rwanda
Published 2025-01-01“…Five districts of the eastern province of Rwanda were prospected using a combination of unbaited light traps and Biogents (BG Sentinel and Pro) traps baited with an artificial human scent during three periods, namely mid-August to mid-September 2021, December 2021, and April to May 2022. …”
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27495
A Network Pharmacology-Based Approach for Exploring Key Active Compounds and Pharmacological Mechanisms of Tangshen Formula for Treatment of Diabetic Nephropathy
Published 2021-01-01“…The occurrence and development of DN are related to multiple factors in the human body, which makes DN a complex disease, and the pathogeneses of DN have not yet been fully illustrated. …”
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27496
Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells
Published 2025-01-01“…Genetically engineered pancreas-specific Kras-mutated, dual specificity phosphatase-2 (Dusp2) knockout mouse models were established. Human and mouse primary pancreatic cancer cell lines were used for in vitro assessment of cancer characteristics. …”
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27497
Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG)
Published 2025-01-01“…Abstract Background Mycobacterium bovis BCG is the human tuberculosis vaccine and is the oldest vaccine still in use today with over 4 billion people vaccinated since 1921. …”
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27498
Immune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression
Published 2025-01-01“…IntroductionThe envelope proteins syncytin-1 and pHERV-W from the Human Endogenous Retroviral family ‘W’ (HERV-W) have been identified as potential risk factors in multiple sclerosis (MS). …”
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27499
Assessment of Knowledge, Attitudes and Needs of Accredited Social Health Activist (ASHA) in Community based Cancer Awareness and Screening Programme: A Mixed Method Study from a Ru...
Published 2025-01-01“…Knowledge about family history and the human papillomavirus as risk factors for cancers of the breast and cervix was inadequate. …”
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27500
Acquisition of innate B cell properties and generation of autoreactive IgA antibodies by follicular B cells during homeostatic proliferation
Published 2025-01-01“…This process could also manifest as clinical complication of therapy-induced lymphopenia in the context of transplantation and cancer in human patients.…”
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