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27381
The Usefulness of the Pressure Algometer in the Diagnosis and Treatment of Orofacial Pain Patients: A Systematic Review
Published 2020-01-01“…The titles and abstracts from electronic search results were screened for keywords and evaluated by two observers, with the following inclusion criteria: published since 1997, written in English, and encompassing human research. Exclusion criteria were as follows: articles published earlier than 1997, not written in English, animal studies, studies with the use of medicaments, and articles examining receptor interactions. …”
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27382
HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis
Published 2025-01-01“…These results provide insights into the mechanism of ATRX's centromeric localization and its critical function in preserving centromeric cohesion by reducing Wapl activity in human cells.…”
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27383
The Metaverse for Industry 5.0 in NextG Communications: Potential Applications and Future Challenges
Published 2025-01-01“…Industry 5.0 is expected to reform the manufacturing processes through human-robot collaboration and effective utilization of technologies like Artificial intelligence for increased productivity and less maintenance. …”
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27384
Testicular Cancer Presenting as Gastric Variceal Hemorrhage
Published 2017-01-01“…The serum alpha-fetoprotein level was 17,090 ng/mL, lactate dehydrogenase was 1480 U/L, and human chorionic gonadotropin was 287.4 IU/mL. Upper endoscopy revealed a type 1 isolated gastric varix, treated with cyanoacrylate. …”
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27385
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Validation of hub genes at mRNA and protein levels was done via GEPIA2 and Human Protein Atlas. Survival analysis was conducted using TCGA data by GEPIA2 and LASSO, and drug sensitivity was analyzed with the GSCA drug bank database, highlighting potential therapeutic targets. …”
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27386
Evaluation of choices and time spent on an open online elective course by undergraduate medical students during the COVID-19 pandemic
Published 2024-06-01“…The most popular courses related to the Leader and Manager role were around decision-making in human resources, problem-solving, and managing healthcare teams. …”
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27387
Deep-learning-based extraction of circle of Willis topology with anatomical priors
Published 2024-12-01“…Abstract The circle of Willis (CoW) is a circular arrangement of arteries in the human brain, exhibiting significant anatomical variability. …”
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27388
A Review on Current Aspects of Curcumin-Based Effects in Relation to Neurodegenerative, Neuroinflammatory and Cerebrovascular Diseases
Published 2024-12-01“…Curcumin is among the most well-studied natural substances, known for its biological actions within the central nervous system, its antioxidant and anti-inflammatory properties, and human health benefits. However, challenges persist in effectively utilising curcumin, addressing its metabolism and passage through the blood–brain barrier (BBB) in therapies targeting cerebrovascular diseases. …”
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27389
Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA
Published 2025-02-01“…ABSTRACT Ixodes scapularis is a vector of several human pathogens in the United States, including Borrelia burgdorferi, the cause of Lyme disease, and Powassan virus (POWV), an emerging cause of severe encephalitis. …”
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27390
Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging
Published 2025-02-01“…New in vitro binding data is also made available for (-)-FEOBV with human-sourced σ1 receptors, revealing a 300-fold stronger affinity for VAChT compared to σ receptors. …”
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27391
Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization
Published 2025-02-01“…Results: In silico analysis showed upregulation of sterol regulatory element-binding protein 2 (SREBP2) and MVP genes, including 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR), farnesyl-diphosphate synthase (FDPS), squalene epoxidase (SQLE), which correlated with worse overall patient survival. Targeting of MVP in human RD and RH30 lines by inhibitors of SREBP2 (fatostatin), HMGCR (lovastatin and simvastatin), and FDPS (zoledronic acid) resulted in impaired cell growth, migration, and viability, and increased oxidative cell death in combination with actinomycin D. …”
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27392
Exogenous organic acids promoted phytoremediation by Hydrangea macrophylla in cadmium‑contaminated soil
Published 2025-01-01“…Cadmium (Cd) contaminants with high toxicity and mobility seriously threatens the ecological environment and human safety. Hydrangea macrophylla is a potential plant for Cd-contaminated soil remediation. …”
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27393
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27394
Sustainability assessment of pectin extraction from Citrus paradisi peel to support the encapsulation of lactic acid bacteria
Published 2025-06-01“…The main impact categories were climate change, human toxicity with carcinogenic effects and depletion of water resources contributing to deionized water and electricity consumption. …”
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27395
Physical education curriculum systematizing based on action research: a collaborative network between teacher-researchers from public schools in Quixadá — Ceará, Brazil
Published 2025-01-01“…For more than forty years, physical education has been associated with human sciences in Brazil, with an emphasis on the dynamics of culture. …”
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27396
Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches
Published 2018-01-01“…In vitro, the biomaterial exhibited an enhanced mechanical strength maintaining a porous ultrastructure, and the constant release of cytokines promoted the proliferation of seeded human mesenchymal stem cells (hMSCs). In vivo, with the hMSC-seeded, cytokine-immobilized patch (MSCs + GF patch), we performed modified SVR for rats with left ventricular aneurysm postmyocardial infarction (MI). …”
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27397
Ontologies in modelling and analysing of big genetic data
Published 2025-01-01“…ONN4MST can distinguish samples from ontologically similar biomes, thus offering a quantitative way to characterize the evolution of the human gut microbial community. Both examples demonstrate high performance and interpretability, making them valuable tools for analyzing and interpreting big data in biology.…”
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27398
Comparative thoracic radiography in healthy and tuberculosis-positive sun bears (Helarctos malayanus)
Published 2025-01-01“…Early and accurate diagnosis of pulmonary tuberculosis (TB) is key to effective outbreak management, and in humans thoracic radiography is used extensively for screening purposes. …”
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27399
Development and progression association of various ophthalmic pathologies with the gut microbiome state (literature review)
Published 2023-11-01“…Modern researches focus on studying the effect of changes in the gut microbiome on human health, including his eyes. This suggests the potential use of this indicator as a non-invasive biomarker during differential diagnosis, as well as its introduction for ophthalmic therapy purposes. …”
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27400
POVEIKIS IR ATSAKAS BIOLOGINIUOSE VYKSMUOSE
Published 2000-01-01“…One of the most important conditionalities is the genetic regulation. In the case of human being an additional higher level conditionalities can be detected: feelings, will and consciousness. …”
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