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26421
Determination of Carbapenemase-Producing OXA- 48 and KPC Genes in Antibiotic-Resistant Gram-Negative Bacilli Isolated from Infectious Samples of Cardiovascular Patients Hospitalize...
Published 2024-12-01“…Background and purpose: Antibiotic resistance remains a serious problem for human health and continues to impact patients in hospitals worldwide. …”
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26422
Huge splenomegaly, a rare presentation of multicentric Castleman’s disease in an HIV-infected patient: a case report and literature review
Published 2024-10-01“…Nowadays, multicentric CD is most commonly observed in individuals infected with human immunodeficiency virus (HIV) type 1, in association with Kaposi’s sarcoma. …”
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26423
A Rare Case of Spontaneous Heterotopic Pregnancy at 12 weeks of Gestation Following Natural Conception With Literature Review
Published 2025-02-01“…The complexity of clinical and laboratory findings complicates its diagnosis, necessitating a high index of suspicion for prompt intervention.Case Presentation: We reported the case of a 36-year-old woman diagnosed with heterotopic pregnancy at 12 weeks of gestation following spontaneous conception, who presented with severe abdominal pain. Initial beta-human chorionic gonadotropin (β-hCG) levels were 57,278.00 mIU/mL. …”
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26424
Research on a traditional Chinese medicine case-based question-answering system integrating large language models and knowledge graphs
Published 2025-01-01“…The system’s performance, evaluated using the RAGAS framework, achieved high scores: 0.9375 in faithfulness, 0.9686 in answer relevancy, and 0.9500 in context recall; In human evaluations, the levels of safety and usability are significantly higher than those of LLMs without using RAG.DiscussionThe results demonstrate that integrating LLMs with a knowledge graph significantly enhances the efficiency and accuracy of retrieving TCM case information. …”
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26425
High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression
Published 2020-01-01“…Our previous study indicated that SET domain-containing protein 8 (SETD8) downregulation is involved in high glucose-mediated endothelial inflammation in human umbilical vein endothelial cells (HUVECs). …”
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26426
Influence of Regional Pollution Outflow on Particle Number Concentration and Particle Size in Airshed of Guangzhou, South China
Published 2022-06-01“…There is a strong local emission (mainly vehicular emissions) in both urban and suburban areas which was significantly lowered during the CNY period due to reduced human activities. The PM pollution was found to be significantly influenced by local emissions (dominated by Aitken mode particles) and new particle formation (NPF) process (dominated by nucleation mode particles). …”
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26427
Sub-District Level Spatiotemporal Changes of Carbon Storage and Driving Factor Analysis: A Case Study in Beijing
Published 2025-01-01“…In future carbon storage prediction, the ecological protection scenario will contribute to achieving the goals of carbon peak and carbon neutrality. (3) Among the various driving factors, slope has the strongest impact on the overall carbon storage in Beijing, followed by Human Activity Intensity (HAI) and Nighttime Light Data (NTL). …”
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26428
Innovative Solid Lipid Nanoparticle-Enriched Hydrogels for Enhanced Topical Delivery of L-Glutathione: A Novel Approach to Anti-Ageing
Published 2024-12-01“…The hydrogel significantly improved antioxidant capacity, protecting human fibroblasts from UVA-induced oxidative stress and enhancing cell viability. …”
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26429
Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis
Published 2025-02-01“…Summary: Antimicrobial resistance poses a severe threat to human health and Pseudomonas aeruginosa stands out among the pathogens responsible for this emergency. …”
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26430
The Risk Assessment of Pesticide Ingestion with Fruit and Vegetables for Consumer’s Health
Published 2021-01-01“…Postharvest control stands out, especially when it comes to products imported from distant countries, resulting in increased concentration of pesticides and risk to human health consuming such products. In this study, analyses of pesticide residues were performed on 200 samples of fruits and vegetables. …”
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26431
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26432
Clinical Comparative Study of Intravitreal Injection of Triamcinolone Acetonide and Aflibercept in the Treatment of Diabetic Retinopathy Cystoid Macular Edema
Published 2022-01-01“…The clinical curative effect, visual acuity, central subfield macular thickness (CSMT), macular volume, scores of quality of life, and levels of cytokines in aqueous humor (vascular endothelial growth factor (VEGF), monocyte chemoattractant protein-1 (MCP-1), human angiopoietin-like protein 4 (ANGPTL4)] at different time points (before and at 6 months after surgery) were compared between the two groups. …”
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26433
The Changes in Biochemical Compositions of Five Different Macroalgae and Seagrass (Halophila stipulacea (Forsskal) Ascherson 1867) Collected from Iskenderun Bay
Published 2022-12-01“…In conclusion, the information of the biochemical compositions of five different macroalgae and Angiosperms/Seagrass (Halophila stipulacea) are important for the evaluation of potential sources for commercial and human consumption. In addition, biochemical compositions of tested macroalgae and seagrass could make important contributions to feed formulations and functional foods in future.…”
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26434
Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection
Published 2019-01-01“…Methods. IL-18 expression in human aorta samples from AD (n=8) and non-AD (NAD, n=7) patients was measured. …”
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26435
SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection
Published 2025-01-01“…Abstract Understanding the neurobiological mechanisms underlying HIV-associated neurocognitive decline in people living with HIV is frequently complicated by an inability to analyze changes across the course of the infection and frequent presence of comorbid psychiatric and substance use disorders. Preclinical non-human primate simian immunodeficiency virus (SIV) models help address these shortcomings. …”
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26436
Association between population viral load surrogate indicator and HIV transmission potential: a prospective cohort study in Xinjiang, China
Published 2025-01-01“…Abstract Background New indicators of potential human immunodeficiency virus (HIV) transmission are being actively explored. …”
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26437
Risk of Nipah Virus Seroprevalence in Healthcare Workers: A Systematic Review with Meta-Analysis
Published 2025-01-01“…Nipah virus (NiV) is a zoonotic pathogen with the potential to cause human outbreaks with a high case fatality ratio. …”
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26438
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26439
Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics
Published 2024-12-01“…While cancer-associated fibroblasts and integrins have been proposed as targets for imaging of pancreatic ductal adenocarcinoma (PDAC), herein, spatial transcriptomics and proteomics of human surgical samples are applied to select PDAC targets. …”
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26440
Penggunaan Compressive Sensing pada Pengenalan Huruf dengan Tulisan Tangan Menggunakan Metode K-Nearest Neighbor
Published 2022-12-01“…Abstract Retrieval, delivery, or exchange of information in the form of data is needed by humans. Human life requires information quickly and precisely, so data are used so it doesn't take up a lot of bandwidth and memory capacity when it arrive at the server. …”
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