The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis by Paulina Marona, Rafał Myrczek, Iga Piasecka, Judyta Gorka, Oliwia Kwapisz, Ewelina Pospiech, Janusz Rys, Jolanta Jura, Katarzyna Miekus

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Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic by Temitope Isaac Adelusi, Abdeen Tunde Ogunlana, Moyosoluwa Precious Oyewole, Taiwo Ooreoluwa Ojo, Olamide Tosin Olaoba, Elijah Kolawole Oladipo, Shopnil Akash, Samir Ibenmoussa, Mohammed Bourhia, Yousef A. Bin Jardan, Baye Sitotaw

“…Additionally, the vaccine’s binding prowess for human toll-like receptors (TLR) (1, 3, 4, and 8) was investigated. …”
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lncRNA NEAT1 Downregulation Ameliorates the Myocardial Infarction of Mice by Regulating the miR-582-5p/F2RL2 Axis by Zhenhua Wu, Yunpeng Bai, Yujuan Qi, Chao Chang, Yan Jiao, Yaobang Bai, Zhigang Guo

“…Oxygen-glucose deprivation- (OGD-) induced human cardiac myocytes (HCMs) were cultured and transfected. …”
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Novel insights into immunopathogenesis and crucial biomarkers between primary open‐angle glaucoma and systemic lupus erythematosus by Yixian Liu, Mengling You, Zhou Zeng, Jing Wang, Rong Rong, Xiaobo Xia

“…Finally, reverse transcription quantitative real‐time polymerase chain reaction (RT‐qPCR) was performed in human trabecular meshwork stem cells to validate the five identified biomarkers. …”
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The promise and challenges of Artificial Intelligence-Large Language Models (AI-LLMs) in obstetric and gynecology by Khanisyah Erza Gumilar, Ming Tan

“…AI-LLM can significantly improve diagnostic accuracy and treatment efficiency by utilizing large medical databases, which is especially useful for dealing with rare diseases that are difficult to document or understand by human practitioners alone. In addition, AI-LLM can provide informed patient care recommendations by analyzing large amounts of data and providing insights based on unique patient profiles, with the added benefit of being accessible 24/7 via the internet. …”
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Effects of metal ion implantation (Fe, Ti, Zn and Zr) on mechanical properties, corrosion resistance and biocompatibility of WE43 Mg alloy by Lianhui Li, Zhiqiang Zhang, Dechuang Zhang, Fugang Qi, Yilong Dai, Wenwen Wei, Xiaoping Ouyang

“…Moreover, the alloys implanted with Fe, Ti and Zn ions significantly promoted proliferation of human umbilical vein endothelial cells (HUVEC) compared with the unmodified alloy. …”
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COVID-19 in patients with severe mental illness: An analysis of in-patients at a psychiatric hospital in Cape Town by Haseena B. Sablay, Qhama Z. Cossie, Deirdre I. Pieterse

“…Reported comorbidities included nicotine use (71%, n = 181), hypertension (11%, n = 28) and human immunodeficiency virus (7%, n = 18). Most patients (62%, n = 156) were symptomatic for COVID-19. …”
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Simulation of Geomagnetically Induced Currents in a Low‐Latitude 500 kV Power Network During a Solar Superstorm by J. J. Zhang, Y. Q. Yu, W. Q. Chen, C. Wang, Y. D. Liu, C. M. Liu, L. G. Liu

“…Abstract Geomagnetically induced currents (GICs) are one of the main manifestations through which space weather affects human technical facilities, and GICs constitute the final link in the solar wind‐magnetosphere‐ionosphere‐ground interaction chain. …”
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3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3 by Yangyun Wang, Chaoliang Shi, Wei Jiao, Xiaoxiang Wan

“…While the toxicological effects of 3-ADON on human and animal health are well-documented, its specific impact on the reproductive system remains underexplored. …”
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Impact of Foliar Application of Zinc and Magnesium Aminochelate on Bean Physiology and Productivity in Ghana by Stephen Yeboah, James Asibuo, Patricia Oteng-Darko, Emmanuel Asamoah Adjei, Maxwell Lamptey, Eric Owusu Danquah, Boaz Waswa, Louis Butare

“…Different approaches including glycine have been used to improve mineral nutrient status of plants toward safer products and improved human health. However, limited research has been undertaken to understand the response of beans to amino Zn and Mg foliar fertilizer application in Ghana. …”
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A Systematic Review and Meta-analysis of Single-group Studies Assessing the Role of Calcium Hydroxylapatite in Aesthetic Enhancements and Satisfaction by Mojgan Amiri, MSc, Renald Meçani, MD, Christa D. Niehot, MSc, Terri L. Phillips, MD, Katherine Goldie, MD, Janina Kolb, MD, Taulant Muka, PhD, Hua Daughtry, PhD

“…Single-group studies with at least 10 human adults were included. Summary measures of patients satisfaction and global aesthetic improvement scores were combined using the generalized linear mixed model. …”
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Effects of Ginsenoside Biopolymer Nanoparticles on the Malignant Behavior of Non-Small-Cell Lung Cancer by Weizheng Zhou, Chengliang Cai, Hui Shi, Hai Jin, Xiaowei Wang

“…The Rg3 monomer and HA-Rg3 nanoparticles mitigated the malignant behavior of human non-small-cell lung cancer H125 cells through the miR-192/PTEN molecular axis, and HA-Rg3 nanoparticles showed better antitumor effects.…”
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Disparities in well-being outcomes among medical students: a comparative study between medical students with and without disability by Henry J. Seaborne, Lara Z. Chehab, Nikhil Rajapuram, Amanda Sammann

“…Trial registration This study does not report the results of a health care intervention on human participants, so trial registration is not required.…”
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Remote and Anesthetic-Induced Myocardial Preconditioning Is Preserved in Atherosclerotic LDL Receptor-/- Mice In Vivo by Walter Petermichl, Kathrin Eglmeier, Henriette Hesse, Michael Gruber, Bernhard Graf, Andre Bredthauer, Andreas Redel

“…In the animal model, preconditioning is a powerful weapon against ischemic damage. The reason why the human heart cannot be protected from ischemic damage by preconditioning remains unclear. …”
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Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro by Dong-Liang He, Ri-Ya Jin, Hui-Zhen Li, Qing-Ye Liu, Zhi-Jun Zhang

“…Compared with free PSO, HA/PSO/C NPs showed notably enhanced cytotoxicity and had the strongest potency to human glioma cell line U251. Conclusion. This study demonstrated that PSO, a novel oligopeptide from Perilla seeds, has a broad-spectrum anticancer effect and could be encapsulated by NPs, which enhanced tumor targeting cytotoxicity with obvious controlled release. …”
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Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands by Virtudes Moreno, Julia Lorenzo, Francesc X. Aviles, M. Helena Garcia, João P. Ribeiro, Tânia S. Morais, Pedro Florindo, M. Paula Robalo

“…Compounds 1, 2, and 3 showed much higher cytotoxicity than the cisplatin against human leukaemia cancer cells (HL-60 cells).…”
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Approaches and applications in transdermal and transpulmonary gene drug delivery by Anni Zhang, Xuran Zhang, Jiahui Chen, Xianbao Shi, Xijuan Yu, Zhonggui He, Zhonggui He, Jin Sun, Jin Sun, Mengchi Sun, Mengchi Sun, Zhijun Liu

“…Gene therapy has emerged as a pivotal component in the treatment of diverse genetic and acquired human diseases. However, effective gene delivery remains a formidable challenge to overcome. …”
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Comparing the Effect of Different Dentin Conditioners on the Microshear Bond Strength of High Viscosity Glass Ionomer Cements to Dentin by Zahra Fattah, Zahra Jowkar, Somayeh Ghafouri, Hajar Farhadpour

“…Background: This study aimed to evaluate the influence of using tannic acid 20% (TA) and polyacrylic acid (PAA) as dentin conditioning agents on the microshear bond strength (µSBS) of two types of high viscosity glass ionomer cements (HVGICs).Materials and Methods: This in vitro study was conducted on 60 extracted human premolars. The occlusal enamel was removed using a high-speed handpiece under water-cooling in order to expose the dentin. …”
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Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats by Lorenzo Di Cesare Mannelli, Daniele Bani, Andrea Bencini, Maria Luisa Brandi, Laura Calosi, Miriam Cantore, Anna Maria Carossino, Carla Ghelardini, Barbara Valtancoli, Paola Failli

“…MnL4 (10−7 M) prevented the lipid peroxidation of isolated human chondrocytes when was produced by RAW 264.7. …”
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Prognostic Value of STMN1 Expression in Non-small Cell Lung Cancer: 
A Meta-analysis by Mengjie LI, Qinghua ZHOU

“…Background and objective Lung cancer is one of the malignant tumors with the highest morbidity and mortality rates worldwide, seriously threatening human health. Non-small cell lung cancer (NSCLC) accounts for more than 85% of all lung cancer cases. …”
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