MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…EMT is involved in multiple physiological and pathological processes in the human body. The occurrence of EMT involves many signal transduction pathways and complex molecular mechanisms related to calnexin, growth factors, transcription factors, and the microenvironment. …”
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In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity by Gianandrea Guidetti, Alessandro Di Cerbo, Angela Giovazzino, Valentina Rubino, Anna Teresa Palatucci, Sara Centenaro, Elena Fraccaroli, Laura Cortese, Maria Grazia Bonomo, Giuseppina Ruggiero, Sergio Canello, Giuseppe Terrazzano

“…Our results showed a significant reduction in interferon- (INF-) γ production by human and canine lymphocytes in presence of botanicals (p⁎<0.05). …”
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Multi-generational exposure of Daphnia magna to pharmaceuticals: Effects on colonization, reproduction, and habitat selection behavior by María Pilar González, Ilaria Cecconi, David Salvatierra, María Úbeda-Manzanaro, Gema Parra, Eloísa Ramos-Rodríguez, Cristiano V.M. Araújo

“…The presence of pharmaceuticals in the aquatic environment is increasing due to their growing use for human health. Although most studies are based on short exposures to these contaminants, the present study has emerged from the need to study pharmaceuticals in aquatic organisms over a long-term exposure to understand any multi-generational chronic effects and alterations regarding habitat selection. …”
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Comparative Effects of Crocin and Losartan on RAGE, TGF‐β, TNF‐α Gene Expression and Histopathological Changes of the Liver Tissue in Rats With Diabetes by Shahnaz Rajabi, Yaser Mohammadi, Hamid Kabiri‐rad, Mahdiyeh Rajabi‐moghaddam, Azam Rezaei Farimani

“…Conclusion Crocin may be a feasible therapeutic agent for treating diabetes and its symptoms when combined with pharmaceutical medications. Human research is still needed to reach clear conclusions.…”
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Semiautomatic volumetry of the temporal lobes of the brain and correlation with electroencephalography results in dogs with assumed idiopathic epilepsy by Paulina Kinga Drobot, Aleksandra Banasik, Karolina Owsińska‐Schmidt, Marcin Wrzosek, Przemysław Podgórski

“…Automated brain volumetry, widely used in human medicine, can now be applied in veterinary medicine because of the availability of brain atlases. …”
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Risk factors for silicotuberculosis among miners: a scoping review by Mansour F. Saliba, Zeina Z. Karam, Moussa El Khayat, Elizabeth Koka, Dana A. Halwani, Joly Ghanawi, Layal Hneiny, Mey Jurdi, Hassan R. Dhaini, Umayya Musharrafieh, Rima R. Habib

“…Findings identified various STB risk factors including demographic factors such as age and sex, lifestyle factors including smoking and alcohol intake, clinical factors such as history of TB, grades of silicosis, and human immunodeficiency virus (HIV), in addition to occupational factors encompassing silica exposure, duration of employment, and type of work setting. …”
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Intratumor heterogeneity of HPV integration in HPV-associated head and neck cancer by Noah Sasa, Toshihiro Kishikawa, Masashi Mori, Rie Ito, Yumie Mizoro, Masami Suzuki, Hirotaka Eguchi, Hidenori Tanaka, Takahito Fukusumi, Motoyuki Suzuki, Yukinori Takenaka, Keisuke Nimura, Yukinori Okada, Hidenori Inohara

“…Abstract Integration of human papillomavirus (HPV) into the host genome drives HPV-positive head and neck squamous cell carcinoma (HPV+ HNSCC). …”
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Marker-assisted breeding of hybrid lines of <i>Triticum dicoccon</i> (Schrank) Schuebl. × <i>Triticum aethiopicum</i> Jakubz. with purple grain by P. I. Stepochkin, E. I. Gordeeva, Е. K. Khlestkina

“…Cereals whose grain contains antioxidants salutary for human health are promising for functional nutrition. …”
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CXCL12 impact on glioblastoma cells behaviors under dynamic culture conditions: Insights for developing new therapeutic approaches. by Wiam El Kheir, Sahar Naasri, Bernard Marcos, Nick Virgilio, Benoit Paquette, Nathalie Faucheux, Marc-Antoine Lauzon

“…In the present study, a custom-made in vitro 3D model with indirect perfusion to mimic IFF at flow rates of 0.5 μL/min and 3 μL/min was used to examine the invasive behavior of F98-rodent-derived and U87-human-derived GBM cells. This model simulated IFF and CXCL12 gradient within an alginate:matrigel-based hydrogel mimicking brain parenchyma. …”
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Fracture resistance and failure mode of three esthetic CAD-CAM post and core restorations by Islam T. Fathey, Amir Shoukry Azer, Islam M. Abdelraheem

“…Materials and methods Thirty-nine single-rooted human maxillary central incisors were endodontically treated. …”
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Object-Level Contrastive-Learning-Based Multi-Branch Network for Building Change Detection from Bi-Temporal Remote Sensing Images by Shiming Li, Fengtao Yan, Cheng Liao, Qingfeng Hu, Kaifeng Ma, Wei Wang, Hui Zhang

“…Buildings are fundamental elements of human environments, and detecting changes in them is crucial for land cover studies, urban expansion monitoring, and the detection of illegal construction activities. …”
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Digital intervention promoting physical activity among obese people (DIPPAO) randomised controlled trial: study protocol by Bruno Pereira, Martine Duclos, Alexandre Mazéas, Aïna Chalabaev, Marine Blond

“…A mixed-model approach will be used to analyse the change in outcomes over time.Ethics and dissemination The research protocol has been reviewed and approved by the Local Human Protection Committee (CPP Ile de France XI, No 21 004-65219). …”
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Decoding Gestures in Electromyography: Spatiotemporal Graph Neural Networks for Generalizable and Interpretable Classification by Hunmin Lee, Ming Jiang, Jinhui Yang, Zhi Yang, Qi Zhao

“…In recent years, significant strides in deep learning have propelled the advancement of electromyography (EMG)-based upper-limb gesture recognition systems, yielding notable successes across a spectrum of domains, including rehabilitation, orthopedics, robotics, and human-computer interaction. Despite these achievements, prevailing methodologies often overlook the intrinsic physical configurations and interconnectivity of multi-channel sensory inputs, resulting in a failure to adequately capture relational information embedded within the connections of deployed EMG sensor network topology. …”
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Assessment of Knowledge Gaps in Cervical Cancer Screening and HPV Vaccination Among Chinese Women: A Comprehensive Population-Based Study by Huang X, Ruan G, Sun P

“…Xinxin Huang,1 Guanyu Ruan,2 Pengming Sun2 1The Ministry of Health, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, People’s Republic of China; 2Laboratory of Gynecologic Oncology, Fujian Clinical Research Center for Gynecologic Oncology, Fujian Matermity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, People’s Republic of ChinaCorrespondence: Guanyu Ruan; Pengming Sun, Email ruangy_fjsfy@163.com; sunfemy@hotmail.comBackground: While studies on cervical cancer screening (CCS) and human papillomavirus (HPV) vaccine uptake exist in China, few have examined both within populations participating in CCS programs.Methods: This cross-sectional, population-based survey included 37,797 women aged 18– 64 years attending gynecological outpatient clinics. …”
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Effects of 20 Weeks of Endurance and Strength Training on Running Economy, Maximal Aerobic Speed, and Gait Kinematics in Trained Runners by Sergio Rodríguez-Barbero, José María González-Ravé, Benedicte Vanwanseele, Daniel Juárez Santos-García, Violeta Muñoz de la Cruz, Fernando González-Mohíno

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Institutional impacts on diversity, equality and inclusion practices: Case Study of Western multinationals and their emerging economy subsidiaries by Emil Velinov, Andreas Hilger, Pawel Dobrzanski

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Dietary Exposure to Aflatoxins in Some Randomly Selected Foods and Cancer Risk Estimations of Cereals Consumed on a Ghanaian Market by Nii Korley Kortei, Theophilus Annan, Seidu A. Richard, Adjoa A. Boakye, Clement O. Tettey, Edward Ken Essuman, Enoch Aninagyei, Precious Agbemeseli

“…Aflatoxins have gained so much reputation among all mycotoxins due to their notoriety in causing countless adverse health effects on humans as well as animals. It continues to be a major concern in food safety globally. …”
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Enhancing patient education on the role of tibial osteotomy in the management of knee osteoarthritis using a customized ChatGPT: a readability and quality assessment by Stephen Fahy, Stephan Oehme, Danko Dan Milinkovic, Benjamin Bartek

“…Two ChatGPT-4 models were compared: a native version and a fine-tuned model (“The Knee Guide”) optimized for readability and source citation through Instruction-Based Fine-Tuning (IBFT) and Reinforcement Learning from Human Feedback (RLHF). The responses were evaluated for quality using the DISCERN criteria and readability using the Flesch Reading Ease Score (FRES) and Flesch-Kincaid Grade Level (FKGL).ResultsThe native ChatGPT-4 model scored a mean DISCERN score of 38.41 (range 25–46), indicating poor quality, while “The Knee Guide” scored 45.9 (range 33–66), indicating moderate quality. …”
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Euphorbia serpens extracts mediated synthesis of copper oxide nanoparticles and their biological applications by Sana Idrees, Banzeer Ahsan Abbasi, Javed Iqbal, Mohsin Kazi

“…With the passage of time there is enormous development in the field of science and technology, however, human health remained the utmost concern. There are different strategies that helps us to treat various diseases but they have adverse reactions on our bodies. …”
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Exploring preconception health in adolescents and young adults: Identifying risk factors and interventions to prevent adverse maternal, perinatal, and child health outcomes-A scopi... by Zahra Ali Padhani, Komal Abdul Rahim, Gizachew A Tessema, Jodie C Avery, Negin Mirzaei Damabi, Patience Castleton, Rehana A Salam, Salima Meherali, Zohra S Lassi

“…Micronutrient supplementation contributed to reducing anaemia among adolescent mothers; however, human papillomavirus (HPV) and herpes simplex virus (HSV) vaccination had little to no impact on stillbirths, ectopic pregnancies, and congenital anomalies. …”
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