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Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease
Published 2025-02-01“…Hippurate, a host-microbial co-metabolite has been associated with human gut microbial gene richness and with metabolic health. …”
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Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR
Published 2025-01-01“…Advanced preclinical models mimicking human tumour microenvironments are needed to refine and optimise this therapeutic approach.…”
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25684
A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer
Published 2024-12-01“…The limited clinical success of previous TRAILR2 agonistic agents, to date, has been ascribed to either poor efficacy or hepatotoxicity. TR2/CDH3 BAB is a human bispecific antibody that relies on binding both CDH3 and TRAILR2 on cell surfaces to achieve TRAILR2 hyperclustering and efficient apoptosis induction by TRAILR2 signaling selectively in CDH3-expressing tumor cells. …”
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25685
Análisis de genotipos, alelos y haplotipos de HLA en un grupo de pacientes con artritis psoriásica: poca frecuencia de alelos comunes
Published 2024-12-01“…La artritis psoriásica es una enfermedad compleja y los antígenos leucocitarios humanos (Human Leukocyte Antigen, HLA) son un factor clave en el desarrollo de la enfermedad. …”
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The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver
Published 2025-03-01“…We showed successful but low efficient triple trafficking by LNP-rAAV2 carrying EGFP, human factor IX (hFIX), and luciferase (luc), due to its encapsulation characteristic. …”
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Carbon footprint reduction practices in the Olympic Games: a policy mobility approach
Published 2025-01-01“…Conducting research in human geography: Theory, methodology & practice. …”
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The paediatric liver transplant experience in Johannesburg, South Africa: A broad overview and update
Published 2024-04-01“…Data were accessed from the Wits Donald Gordon Medical Centre Paediatric Liver Transplant Research Database (University of the Witwatersrand Human Research Ethics approval: M190749). The following data were collected: donor and recipient sociodemographic and clinical characteristics, details of transplant procedures, donor grafts and recipient outcomes (post-operative complications, graft and recipient survival). …”
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INTERNATIONAL FORUM OF AMERICAN SOCIETY FOR ENGINEERING EDUCATION
Published 2016-12-01“…The focus in the Vision is on innovations, human resource training, and national quality infrastructure and technology development.The plenary session reports showed that the main trends in both parts of the world today are very similar. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases
Published 2025-02-01“…NRF2 controls the expression of more than 250 human genes that share in their regulatory regions a cis-acting enhancer termed the antioxidant response element (ARE). …”
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Presenting the entrepreneurial school model in Iran
Published 2024-11-01“…Education and training and professional development of entrepreneurial teachers and professors, who have a positive attitude and are committed to the development of entrepreneurship and have the necessary scientific ability, knowledge and skills, should be taken into consideration in the centers related to the recruitment, cultivation and evaluation of entrepreneurial human resources.…”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…The mountain peaks have an altitude of 822 m and the main human occupations are distributed at an altitude of 700-800 m. …”
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Investigating and prioritizing the factors affecting the success of e-commerce using the best and worst (BWM) technique.
Published 2024-05-01“…Advances in information and communication technology and the rapid expansion of the Internet have undergone many changes and transformations in various areas of human life, as well as in various business fields. …”
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Blood and Iron: The Rise and Fall of the German Empire 1871 – 1918
Published 2024-12-01“… It is always very interesting to read the German history, which sheds light on a nation which has been built in less than two centuries and hit almost the top of Human Development Index. The origins of its economic and political dominance can be traced back to the beginning of the German Empire’s formation. …”
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Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest...
Published 2024-12-01“…In general, it can be said that cooperatives, as economic and social organizations, have the necessary power and capacity to organize different classes and groups of people to create sustainable human development, and during the economic recession, they play an effective role in creating stable employment and income generation (Shadmehri, Ahmad 2005).Case studyThe statistical population of the research included the collection of managers, supervisors, and employees of cooperatives located in Sistan and Baluchistan province in the number of 345 people, out of which 182 people were randomly selected as the sample group.Materials and methodsThe current research is of an applied type, Also, this research is one of the empirical research in the field of management. …”
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Designing a model for fostering organizational resilience based on organizational agility components
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戶外教育課程評估指標建構之研究 Indicators for Evaluating Outdoor Education Curricula
Published 2024-12-01“…Unlike other educational approaches, outdoor education involves leveraging outdoor environments to foster human–nature interactions, thereby conferring psychological, physiological, social, and educational benefits; this is the most unique feature of outdoor education. …”
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