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25141
Profiling gene alterations in striatonigral neurons associated with incubation of methamphetamine craving by cholera toxin subunit B-based fluorescence-activated cell sorting
Published 2025-02-01“…IntroductionIn both rats and humans, methamphetamine (Meth) seeking progressively increases during abstinence, a behavioral phenomenon termed “incubation of Meth craving”. …”
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25142
Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1...
Published 2025-02-01“…Abstract Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. …”
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25143
ONLINE PROJECTS AS A FORM OF SPREADING PEDAGOGICAL BIOGRAPHICAL KNOWLEDGE IN THE CONTEXT OF OPEN SCIENCE
Published 2023-10-01“…The article reveals thetrend of an increase in the number of biographical online projects in the Ukrainian segment of the Facebook social network during 2020–2022, caused by the decolonization of the Ukrainian humanities. 4 proven models for implementing biographical online projects have been proposed for a widespread use: "Online project on Facebook", "Online project on Facebook and Instagram", Online project on Facebook using a web portal/website", Online project on Facebook as a source ofvirtual exhibition on the website". …”
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25144
Viral Transcript and Tumor Immune Microenvironment-Based Transcriptomic Profiling of HPV-Associated Head and Neck Squamous Cell Carcinoma Identifies Subtypes Associated with Progno...
Published 2024-12-01“…Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HPV-positive HNSCC) has distinct biological characteristics from HPV-negative HNSCC. …”
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25145
Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis
Published 2025-01-01“…However, their extensive use, accumulation, and biomagnification pose significant risks to humans. Increasing evidence has suggested that NEOs may affect glucose homeostasis, but little research has linked NEOs exposure to gestational diabetes mellitus (GDM), which is the most common disease in pregnancy. …”
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25146
Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response
Published 2025-01-01“…Although individual impacts on the epigenome have been described using different model systems, the phenotypic complexity in humans remains to be elucidated. Here, we make use of a natural inflammatory response occurring during coronavirus disease 2019 (COVID-19), to understand the association of these mutations with inflammatory morbidity (acute respiratory distress syndrome [ARDS]) and mortality. …”
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25147
Revealing the diversity of Fusarium micromycetes in agroecosystems of the North Caucasus plains for replenishing the State Collection of Phytopathogenic Microorganisms of the All-R...
Published 2022-01-01“…The State Collection of Phytopathogenic Microorganisms of the ARSRIP is the State Depository of Phytopathogenic microorganisms that are non-pathogenic to humans or farmed animals. Currently, it has more than 4,500 accessions of plant pathogenic strains of fungi, oomycetes, bacteria, viruses, phytoplasmas, and the collection is updated annually. …”
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25148
Smallpox vaccination in a mouse model
Published 2023-11-01“…The monkeypox epidemic, which became unusually widespread among humans in 2022, has brought awareness about the necessity of smallpox vaccination of patients in the risk groups. …”
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25149
Changes in movement patterns in relation to sun conditions and spatial scales in wild western gorillas
Published 2024-04-01“…This suggests that gorillas navigate their home range by relying on visual place recognition but do not use the sun azimuth as a compass. Like humans, who rely heavily on vision to navigate, gorillas should benefit from better lighting to help them identify landmarks as they move through shady forests. …”
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25150
Seasonal Variation in Antimicrobial Activity of Crude Extracts of Psammaplysilla sp. 1 from Phillips Reef, South Africa
Published 2021-01-01“…Marine invertebrates constitute a diverse group of marine organisms beneficial to humanity due to their therapeutic significance. The marine sponge species Psammaplysilla sp. 1 was collected from Philips Reef, South Africa, over a four-season period and assayed for antimicrobial potential. …”
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25151
A systematic review of the transformation of Lake Beseka from brine to nearly fresh lake water
Published 2025-01-01“…Previously, it was believed that volcanic lakes were harmful to the environment and unusable for the welfare of humans, animals, and other living things. However, LB in Ethiopia is a special or uncommon case to leave doubt to this general believes. …”
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25152
The effects of glucose, nitrate, and pH on cultivation of Chlorella sp. Microalgae
Published 2021-01-01“…<strong>BACKGROUND AND OBJECTIVES: </strong>Bioenergy is a phenomenon that has attracted humans’ attention for about a century. The desirable biological properties of <em>chlorella sp.…”
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25153
A novel placement method of a calibration‐free pH capsule for continuous wireless measurement of intragastric pH in horses
Published 2025-01-01“…A wireless capsule has been designed for continuous esophageal pH monitoring in humans. Objectives To (1) determine the feasibility and describe the methodology of measuring intragastric pH wirelessly in horses; and (2) determine attachment duration of the capsules. …”
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25154
Post-Marketing Pharmacovigilance of Canakinumab from the FDA Adverse Event Reporting System (FAERS)
Published 2025-01-01“…<b>Background:</b> Canakinumab, a humanized anti-IL-1β monoclonal antibody, is known for its ability to suppress IL-1β-mediated inflammation. …”
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25155
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…Sodium 2-mercaptoethane sulfonate (Mesna) has traditionally been employed in clinical practice to counter cyclophosphamide-induced cystitis in humans. However, cyclophosphamide has been employed in developing animal models of interstitial cystitis in in vivo studies. …”
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25156
Under a not so white sky: visual impacts of stratospheric aerosol injection
Published 2025-01-01“…We compare the simulated changes in color and brightness to experimental measurements of minimum thresholds humans can detect. The three aerosol types cause similar changes, except most notably the diamond aerosol increases brightness of the solar aureole by roughly three to five times less than do H _2 SO _4 or CaCO _3 . …”
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25157
Importance and fitness of family medicine milestone project from America to Taiwan
Published 2025-01-01“…Results In IPA, a total of 72.7% (16/22) of the sub-competencies exhibited high importance and fitness, with a mean score ≥ 4.7; the exceptions were PC-1 (cares for acutely ill or injured patients), MK-2 (critical thinking skills in patient care), SBP-1 (cost-conscious medical care), PBLI-3 (improves systems), PROF-3 (humanism/cultural proficiency), and ICS-4 (utilizes technology). …”
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25158
Complete Genome Sequence of Photobacterium damselae Subsp. damselae Strain SSPD1601 Isolated from Deep-Sea Cage-Cultured Sebastes schlegelii with Septic Skin Ulcer
Published 2019-01-01“…Photobacterium damselae subsp. damselae (PDD) is a Gram-negative bacterium that can infect a variety of aquatic organisms and humans. Based on an epidemiological investigation conducted over the past 3 years, PDD is one of the most important pathogens causing septic skin ulcer in deep-sea cage-cultured Sebastes schlegelii in the Huang-Bohai Sea area and present throughout the year with high abundance. …”
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25159
Cowpea cropping systems, traits preference and production constraints in the upper west region of Ghana: farmers' consultation and implications for breeding
Published 2023-06-01“…Walp) is used primarily as food for humans and feed for animals. It is also used for soil management within a cropping system. …”
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25160
Biogenic Amines and Aflatoxins in Some Imported Meat Products: Incidence, Occurrence, and Public Health Impacts
Published 2020-01-01“…Since the beginning of humanity, the global burden of foodborne disease has had a decimating effect on populations, with biogenic amines (BAs) and aflatoxins in meat products implicated. …”
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