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25121
Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents
Published 2025-02-01“…Its etiologic agent, the Mycobacterium tuberculosis (Mtb), is a slow-growing bacterium that has coexisted in humans for thousands of years. According to the World Health Organization, 10.6 million new cases of TB and over 1 million deaths were reported in 2022. …”
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25122
Silver (Ag) doped graphitic carbon nitride (g-C3N4)/biochar composite photocatalyst for improved photocatalytic degradation of ciprofloxacin (CIP)
Published 2025-01-01“…Dumping pharmaceutical wastewater into aquatic bodies vigorously adds to environmental pollution and amplifies antibiotic-resilient bacteria (ARB), a potential danger to humans and living organisms. Among several wastewater treatment methods, the photocatalysis approach under the umbrella of advanced oxidation processes (AOPs) offers a sustainable, inexpensive, and comprehensive treatment of emerging pharmaceutical pollutants (PEPs). …”
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25123
Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models
Published 2025-01-01“…<b>Methods:</b> We leveraged unique mouse models of IL6 trans-signaling that we developed that recapitulate the production of active sIL6R in a genotypic and quantitative fashion observed in humans. Given that the SOD1 transgenic mouse is one of the most highly studied and characterized models of ALS, we bred <i>SOD1<sup>G93A</sup></i> mice with IL6R trans-signaling mice to determine how enhanced trans-signaling influenced symptom onset and pathological processes, including neuromuscular junction (NMJ) denervation, glial activation and motoneuron (MN) survival. …”
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25124
Positive Correlation Between Serum Limonene Levels and Muscle Health in a Representative Adult Population in the United States
Published 2025-01-01“…However, the impact of monoterpene exposure on muscle strength and mass in humans remains unclear. <b>Methods</b>: To explore this relationship, we analyzed data from 1202 adults (aged ≥ 18 years) who participated in the 2013–2014 National Health and Nutrition Examination Survey (NHANES), focusing on serum levels of three specific monoterpenes—α-pinene, β-pinene, and limonene—and their association with hand grip strength and lean muscle mass. …”
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25125
Impact of Combined Acidic and Hyperosmotic Shock Conditions on the Proteome of Listeria monocytogenes ATCC 19115 in a Time-Course Study
Published 2019-01-01“…Listeria monocytogenes can cause listeriosis in humans through consumption of contaminated food and can adapt to and grow under a wide array of physiochemical stresses. …”
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25126
Hematopoietic stem cell discovery: unveiling the historical and future perspective of colony-forming units assay
Published 2025-01-01“…In this review, we explore the fundamental discoveries concerning the CFUs assay by covering the following aspects: (i) the historical overview of the CFUs assay for the study of clonal hematopoiesis involving multilineage potential of HSPCs, (ii) its use in various experimental models comprising humans, mice/rodents, zebrafish and induced pluripotent stem cells (iPSCs) and (iii) research gaps and future direction concerning the role of CFUs assay in clinical and basic sciences. …”
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25127
Ethnobiological survey on medicinal plants used by gaddi and gujjar tribes of riparian region of Beas River of Himachal Pradesh in North Western Himalayas, India
Published 2025-01-01“…This study aimed to record the traditional knowledge of the tribal communities in Himachal Pradesh concerning the use of medicinal plants for treating diseases in humans and livestock. Despite this richness, there is a lack of detailed documentation about the use of therapeutic plants in this area. …”
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25128
Assessment of technogenic pollution by silver compounds on the biological properties of the soil (model experiment)
Published 2024-12-01“… Introduction: Silver (Ag) has increasingly become one of the priority pollutants of soils, which is accompanied by a number of consequences for humans and soil biota. To fully assess the effects of the entry of different chemical forms of Ag into soils, it is necessary to conduct experiments with different types of soils, different exposure periods, as well as a wide range of biological indicators. …”
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25129
Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)
Published 2025-01-01“…The porcine digestive system is physiologically similar to that of humans, making pigs a suitable model for studying DON-induced enterotoxicity. …”
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25130
Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae
Published 2025-02-01“…Background: Angiostrongylus cantonensis is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and can aid in penetrating host defensive barriers in helminths. …”
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25131
Antimicrobial Resistance Profile of E. coli Isolated from Raw Cow Milk and Fresh Fruit Juice in Mekelle, Tigray, Ethiopia
Published 2018-01-01“…They cause great suffering and are transmitted directly or indirectly between animals and humans and circulate in the global environment. E. coli are among them, causing a major public health problem. …”
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25132
A Toxicological Evaluation of Methylliberine (Dynamine®)
Published 2019-01-01“…Future studies are encouraged to corroborate the safety, and assess efficacy, of methylliberine in humans.…”
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25133
Hydrogeochemistry of Surface and Ground Water in Alatening Village, Northwest Region, Cameroon
Published 2020-01-01“…Electrical conductivity and total dissolved solids (TDS) were low implying low mineralised water which can also lead to shortage of important minerals in humans. All the essential ions were found within the WHO guideline values without any significant change in concentrations between seasons (p>0.05). …”
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25134
BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function
Published 2025-01-01“…Bisphenol Z (BPZ) is used as an alternative to BPA, and humans are widely exposed to BPZ through various routes. …”
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25135
<i>Ehrlichia</i> Species in Dromedary Camels (<i>Camelus dromedarius</i>) and Ruminants from Somalia
Published 2025-01-01“…Ehrlichioses, caused by <i>Ehrlichia</i> species, are tick-borne diseases (TBDs) that affect animals and humans worldwide. This study aimed to investigate the molecular occurrence of <i>Ehrlichia</i> spp. in 530 animals (155 Dromedary camels, 199 goats, 131 cattle, and 45 sheep) in the Benadir and Lower Shabelle regions of Somalia. …”
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25136
Pathogen community composition and co-infection patterns in a wild community of rodents
Published 2024-02-01“…Rodents are major reservoirs of pathogens that can cause disease in humans and livestock. It is therefore important to know what pathogens naturally circulate in rodent populations, and to understand the factors that may influence their distribution in the wild. …”
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25137
Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers
Published 2025-01-01“…Furthermore, we have studied the correlation between the levels of this SPM and several pathology indicators, finding a significant correlation between increased LXA4 levels and a better prognosis of the patients.ConclusionWe propose to measure systemic LXA4 as a new promising biomarker to predict the survival in patients affected by SARS-CoV-2 and presumably to other viruses that can affect humanity in the future.…”
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25138
Correlation Between <i>Cryptococcus</i> Infection and the Nasal Mycobiota in a Population of Free-Ranging Koalas (<i>Phascolarctos cinereus</i>) in New South Wales, Australia
Published 2025-01-01“…Cryptococcosis is a fungal disease in humans and animals, caused by the <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i> species complexes. …”
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25139
The expression of apoptosis-regulating proteins Bcl-2 and Bad in liver cells of C57Bl/6 mice under light-induced functional pinealectomy and after correction with melatonin
Published 2021-06-01“…The presence of humans and animals under long-term continuous lighting leads to a suppression of melatonin synthesis, that is, to light-induced functional pinealectomy (LIFP), and the development of desynchronosis. …”
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25140
Therapeutic potential of the neutralizing monoclonal antibody 45G3 against encephalomyocarditis virus
Published 2025-01-01“…Although EMCV rarely triggers severe clinical symptoms in humans, its widespread prevalence and unique biological characteristics underscore the need for continuous surveillance and the development of effective therapeutics and prophylactics. …”
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