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21681
Eating difficulties among Nigerian community-dwelling stroke survivors: prevalence, correlates, and association with quality of life
Published 2025-02-01“…Abstract Background Eating ability is central to human existence and survival, societal acceptance, life satisfaction, and social participation. …”
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21682
The potential impact of glycine supplementation on the process of aging
Published 2025-02-01“…Nevertheless, the evidence base is still evolving; most current data derive from animal models, in vitro experiments, and limited human trials. Rigorous, long-term, randomized controlled studies are needed to identify optimal dosing, determine long-term safety, and clarify whether glycine can be strategically leveraged as an anti-aging nutrient. …”
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21683
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21684
Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screening
Published 2025-02-01“…Sensitivity was related to MYCN status, a marker associated with adverse outcome across human cancers including WT. The combination of the three culture techniques represents a promising tool to both explore tumor heterogeneity in vitro and to facilitate characterization of candidate driver genes, in order to improve treatment regimens in the future.…”
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21685
Implementasi Model Design Thinking pada Prototype Aplikasi E-Growth
Published 2022-12-01“…Abstract The rapid development of technology has many influences on the human side of life. The role of this technological development can help improve the quality of health in Indonesia, one of which is in recording child development stored on smartphones. …”
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21686
Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation
Published 2025-01-01“…The anti-inflammatory and anti-obesity activities of C-Akm extract were studied by testing the extract (50 μg/mL) on the polarization of THP-1 into macrophages, the secretion of pro-inflammatory cytokines in LPS-stimulated PBMCs, and the secretion of leptin and adiponectin in adipospheroids derived from human adipose stem cells. Finally, the extract was examined in 3D co-culture model mimicking inflamed obese adipose tissue. …”
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21687
Evaluation of Chitosan Hydrogel for Sustained Delivery of VEGF for Odontogenic Differentiation of Dental Pulp Stem Cells
Published 2019-01-01“…Vascular endothelial growth factor (VEGF) plays a crucial role in dentin regeneration; however, its constant administrations in the human body is still problematic. Chitosan was widely studied as an effective carrier to deliver bioactive molecules in regenerative medicine. …”
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21688
Nature, prevalence and determinants of mental health problems experienced by adolescents in south Asia: a systematic reviewResearch in context
Published 2025-02-01“…Summary: Background: Adolescence is a sensitive phase of human development where individuals, aged 10–19 years, are particularly vulnerable to developing mental health problems (MHPs). …”
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21689
AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist
Published 2025-01-01“…To address these issues, we introduce AiGPro, a novel multitask model designed to predict small molecule agonists (EC50) and antagonists (IC50) across the 231 human GPCRs, making it a first-in-class solution for large-scale GPCR profiling. …”
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21690
A Shared Path: Co-occurrence and Clinical Implications of Celiac Disease and Type 1 Diabetes Mellitus
Published 2025-01-01“…Both diseases share common genetic factors, such as human leukocyte antigens: HLA-DQ2 and HLA-DQ8. Apart from that, they share environmental factors such as gluten exposure, viral infections, and alterations in gut microbiota composition. …”
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21691
Risk barriers and sustainability in payment for ecosystem service implementation in smallholder forestry
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21692
A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome
Published 2025-12-01“…The evolutionary conservation analysis of the identified Axin-2 mutant was analyzed among 15 vertebrates from human to zebrafish. The protein structure change was analyzed between the wild-type and mutation-type. …”
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21693
Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…Huiqin Zhou,1– 3,* Yunjia Peng,2,3,* Xinhua Huo,2,3 Bingqing Li,2,3 Huasheng Liu,4 Jian Wang,3,5 Gaihua Zhang1 1College of Life Sciences, Hunan Normal University, Changsha, People’s Republic of China; 2Hunan Guangxiu Hospital, Hunan Normal University, Changsha, People’s Republic of China; 3National Engineering Center of Human Stem Cell, Changsha, People’s Republic of China; 4Department of Radiology, The Third Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 5The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gaihua Zhang, The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China. …”
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21694
Influence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study
Published 2025-01-01“…The different surfaces were cultured with human osteoblastic cells; cell adhesion was determined at 3 and 14 days, and the degree of mineralization was determined at 14 days via alkaline phosphatase levels. …”
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21696
Evaluation of mineral and near-infrared forecasting of wheat yield varieties using spectrophotometric techniques
Published 2024-01-01“…BACKGROUND AND OBJECTIVE: Iron, an essential micronutrient, significantly contributes to growth, immune health, and cognitive development in human health. Inadequate dietary iron intake leads to iron deficiency anemia, affecting nearly 1.6 billion people, especially pregnant women and preschool children. …”
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21697
MXene-based materials for enhanced water quality: Advances in remediation strategies
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21698
Development of an Integrated Model of Planning and Management in Free Zones with an Emphasis on Environmental Pressures
Published 2024-03-01“…This research is dedicated to the comprehensive management of the cities within the Aras Azad region, emphasizing a balanced approach to environmental management that encompasses the natural, human, and physical dimensions. The objective is to design a framework that facilitates integrated urban management, thereby promoting sustainable development in the area. …”
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Construction and characterization of chimeric FcγR T cells for universal T cell therapy
Published 2025-01-01“…The cytotoxicity of 64-8a CFR T cells was significantly inhibited by free human IgG at a physiological dose (P < 0.001), which was not observed in 16s3, 32-8a CFR T cells. …”
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