SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

“…We checked for the presence of SIRT2 in human AD patients as well as the mouse model APP/PS1 and finally, we selectively ablated SIRT2 in the astrocytes of APP/PS1 mice to observe its effects on pathology. …”
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Improving Sleep Disorder Diagnosis Through Optimized Machine Learning Approaches by Md. Atiqur Rahman, Israt Jahan, Maheen Islam, Taskeed Jabid, Md Sawkat Ali, Mohammad Rifat Ahmmad Rashid, Mohammad Manzurul Islam, Md. Hasanul Ferdaus, Md Mostofa Kamal Rasel, Mahmuda Rawnak Jahan, Shayla Sharmin, Tanzina Afroz Rimi, Atia Sanjida Talukder, Md. Mafiul Hasan Matin, M. Ameer Ali

“…Classifying sleep disorders, such as obstructive sleep apnea and insomnia, is crucial for improving human quality of life due to their significant impact on health. …”
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Analisis Kualitas Website HSP Academy (PT. Hanosen Pratama) Menggunakan Metode Webqual 4.0 dan Importance and Performance Analysis (IPA) by Anisah Ikhsawiyanthi, Satrio Hadi Wijoyo, Yusi Tyroni Mursityo

“…Abstract HSP Academy is a training company located in Tangerang and aims to assist in developing human resources. HSP Academy has been registered by both national and international certification bodies. …”
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An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401) by Seyyed Mojtaba Shahraeini, Heidar Najafi, Seyyedamir Abbaszade, Mahdi Khosravi, Iman Akbari

“…Objective Issues related to public sector human resources management, particularly those concerning service compensation and annual salary increases for employees, are among the most critical decision-making areas for government managers and parliamentarians in the drafting and approval of annual budget laws. …”
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Anti-inflammatory coupled anti-angiogenic airway stent effectively suppresses tracheal in-stents restenosis by Yanan Zhao, Yiming Liu, Jiheng Shan, Xiaohong Xu, Chengzhi Zhang, Zaoqu Liu, Xiaomeng Li, Zhaoqian Zhong, Yanxia Gao, Kewei Ren, Dechao Jiao, Jianzhuang Ren, Ping Wu, Yong Jiang, Xinwei Han

“…It also displayed anti-proliferative and anti-angiogenic properties on human umbilical vein endothelial cells and lung fibroblasts. …”
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Application of dynamic systems modeling approach to rank optimal urban waste management strategies using SWOT method by Hamid Shahbandarzadeh, Mohammad Hossein Kabgani

“…Environmental issues are also at the top of all human problems.Originality/Value:  In this research, an attempt has been made to examine innovation from three aspects: theoretical, technical and practical gaps, which can be mentioned as the strengths of the current research compared to other research. …”
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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Hazardous heavy metals, particularly cadmium (Cd), are widely distributed in the environment and cause oxidative stress in various animal and human organs. Clove oil (CLO), a common aromatic spice, has been used as a traditional medication as it has potent anti-inflammatory, antioxidant, and hepatoprotective properties. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…The visually-based immunochromatographic test (ICT) described herein allows for quick detection and quantification of IgG and IgM FH-FHAA complexes in human EDTA-plasma or serum. This ICT offers improved detection of FHAAs compared to ELISA as demonstrated by cases where the ICT identifies FH-FHAA complexes in samples that tested negative with the free FHAA ELISA. …”
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Perbandingan Prediksi Penggunaan Listrik dengan Menggunakan Metode Long Short Term Memory (LSTM) dan Recurrent Neural Network (RNN) by Nurfatima Selle, Novanto Yudistira, Candra Dewi

“…Abstract Electrical energy has become one of the most important needs and helped human life nowadays. The electrical energy that cannot be stored for a long time and must always be distributed leads to an obligation for electricity providers to provide appropriate electrical energy. …”
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Designing and Modeling Digital Transformation in the Automotive Industry: Leveraging the Fourth Industrial Revolution by Mohammad Saeed Mozafari Mehr, Mohammad Taghi Taghavifard

“…Conclusion Based on the research paradigm model, it was determined that digital infrastructure, digital leadership, digital human resources, and digital marketing affect digital transformation in Iran Khodro Company. …”
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Detection and Classification of Teacher-Rated Children’s Activity Levels Using Millimeter-Wave Radar and Machine Learning: A Pilot Study in a Real Primary School Environment by Tianyi Wang, Takuya Sakamoto, Yu Oshima, Itsuki Iwata, Masaya Kato, Haruto Kobayashi, Manabu Wakuta, Masako Myowa, Tokomo Nishimura, Atsushi Senju

“…Traditional assessments of children’s health and behavioral issues primarily rely on subjective evaluation by adult raters, which imposes major costs in time and human resource to the school system. This pilot study investigates the utilization of millimeter-wave radar coupled with machine learning for the objective and semi-automatic detection and classification of children’s activity levels, defined as restlessness, within a real classroom environment. …”
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Mesenchymal stem cell-derived extracellular vesicles enriched with miR-124 exhibit anti-inflammatory effects in collagen-induced arthritis by Guo Zhonghua, He Mengyuan, Shi Dongliang, Zhang Zhongbo, Wang Lisha, Ren Bowen, Wang Yunfei, Wang Junjie, Yang Shaoxiang, Yu Hongchao

“…This study investigated the anti-inflammatory effects of human umbilical cord-derived MSC (hUCSC)-EVs overexpressing miR-124 in collagen-induced arthritis (CIA). hUCSCs were transfected with miR-124, and hUCSC-EVs were isolated and characterized. …”
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Comparing International Guidelines for the Remission of Hypertension After Bariatric Surgery by Carina Vieira Dias, Ana Lúcia Silva, Joana Dias, Paulo Cardoso, Rute Castanheira, Andreia Fernandes, Filipa Nunes, Tina Sanai, Mercedes Sanchez, João Maia-Teixeira, Ana Luísa De Sousa-Coelho

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Bleomycin pollution and lung health: The therapeutic potential of peimine in bleomycin-induced pulmonary fibrosis by inhibiting glycolysis by Kangchen Li, Xuefang Liu, Ruilong Lu, Peng Zhao, Yange Tian, Jiansheng Li

“…The increasing use of anticancer drugs has led to the emergence of environmental contaminants such as bleomycin (BLM), which poses significant threats to both aquatic ecosystems and human health. Bleomycin, known for its DNA-damaging properties, is extensively used in oncology. …”
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A qualitative research on career expectations of civilian nurses in military hospitals (军队医院文职护理人员职业期待的质性研究) by CAI Aini (蔡爱旎), HONG Hanhan (洪涵涵), LU Jiaojiao (卢姣姣), JI Dandan (季丹丹), SHANG Yanjun (尚彦君)

“…Objective To investigate the true career expectations of civilian nurses in military hospitals, so as to provide reference for relevant administrators to formulate plans of human resource management and career development. …”
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The Linda Kizazi study: a comparison of morbidity and mortality from birth to 2 years between children who are HIV-unexposed and HIV-exposed, uninfected in the era of universal ant... by John Kinuthia, Dara A Lehman, Dalton Wamalwa, Brenda Wandika, Emily R Begnel, Ednah Ojee, Judy Adhiambo, Eliza Mabele, Vincent Ogweno, Efrem S Lim, Soren Gantt, Jennifer Slyker

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Effect on OPU/IVEP success of different applications for synchronizing follicular waves prior to superstimulation in holstein heifers by M. F. Çiftçi, Ö. F. Yeşilkaya, S. Ü. Çizmeci, M. Gölbaşı, A. Sarı, D. A. Dinç

“…In contrast to GnRH <span class="inline-formula">+</span> P4, hCG <span class="inline-formula">+</span> P4 was performed with 1500 IU hCG (human chorionic gonadotropin) injection instead of GnRH. …”
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The influence of HIV infection on myocardial fibrosis diagnosed by cardiac magnetic resonance imaging in adults: a systematic review and meta-analysis of observation studies by Katongo Hope Mutengo, Katongo Hope Mutengo, Bruno Bezerra Lima, Wilbroad Mutale, Aggrey Mweemba, Lorrita Kabwe, Clive Banda, Callistus Kaayunga, Mutale Mulenga, Douglas Heimburger, Sepiso K. Masenga, John Jeffrey Carr, Annet Kirabo

“…IntroductionHuman immunodeficiency virus (HIV) infection is linked to myocardial fibrosis. …”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…The predicted pharmacokinetic characteristics of absorption, distribution, metabolism, excretion, and toxicity (ADMET) attest to the well-absorbed nature of the isolated compounds, with human intestinal absorption (HIA) varying from 42% for arbutin (M3) to 100% for ursolic acid (M4).ConclusionIn conclusion, the leaves of Ferula communis are a good source of natural antioxidants and phenolic compounds. …”
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Probe – Integrated electrochemical sensing platform for detection of trace levels of Dapoxetine hydrochloride drug residue in water and drug formulations by H. Alwael, N.A. Asiri, B.G. Alhogbi, A.S. Alharthi, E.A. Bahaidarah, T.N. Abduljabbar, D.F. Baamer, M. Madkour, F.A. Zainy, M.S. El-Shahawi

“…The extensive use and misuse of selective serotonin reuptake inhibitors (SSRIs) in drug formulations has resulted in their accumulation in food sources and environment, posing noteworthy threats to human health and the global economy. Dapoxetine hydrochloride (DPH) is one of the recent oral drugs frequently misused for the treatment of male sexual dysfunction of premature ejaculation and has lately international attention. …”
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