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21481
Equalizer Design: HBOA-DE-trained radial basis function neural networks
Published 2025-03-01Get full text
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21482
Potential roles of cigarette smoking on gut microbiota profile among Chinese men
Published 2025-01-01“…Abstract Background Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results. …”
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21483
Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City
Published 2024-03-01“…Abstract Carbonaceous components are important components of fine atmospheric particulate matter (PM2.5) and can affect the local environment, climate, and human health. In this study, online observation data from September 1, 2022, to August 31, 2023, were used to analyze the carbonaceous components, namely, organic carbon (OC) and elemental carbon (EC), in PM2.5 in Jincheng, which is a typical industrial city. …”
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21484
Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility
Published 2025-01-01“…Additionally, correlations were found between the presence of human papillomavirus (HPV) and sexually transmitted bacteria, as well as <i>Gardnerella vaginalis</i>. …”
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21485
Polygenic height prediction for the Han Chinese in Taiwan
Published 2025-02-01“…Abstract Human height prediction based on genetic factors alone shows positive correlation, but predictors developed for one population perform less well when applied to population of different ancestries. …”
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21486
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21487
Environmental and health risk assessment of polycyclic aromatic hydrocarbons and toxic elements in the red sea using Monte Carlo simulation
Published 2025-02-01“…The study evaluated environmental and human health risks using a multifaceted approach, including cluster analysis, principal component analysis, and various indices (HPI, RI, MI, HQ, HI, and CR). …”
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21490
Virulence potential of faecal <i>Escherichia coli</i> strains isolated from healthy cows and calves on farms in Perm Krai
Published 2022-09-01“…Cattle are a reservoir of pathogenic and potentially pathogenic Escherichia coli (E. coli) strains, which can pose a threat to human and animal health. The aim of the study was to evaluate the occurrence of 22 virulence-associated genes (VAGs), as well as the prevalence of antimicrobial drug resistance and three different bla-genes among 49 E. coli strains isolated from healthy cattle. …”
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21491
Penerapan Algoritma Deep Learning Convolutional Neural Network Dalam Menentukan Kematangan Buah Jeruk Manis Berdasarkan Citra Red Green Blue (RGB)
Published 2023-02-01“…Observations in this way have several weaknesses, namely the presence of human visual limitations, being influenced by the psychological condition of the observations and taking a long time, especially for large plantations. …”
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21492
Development of Cephradine-Loaded Gelatin/Polyvinyl Alcohol Electrospun Nanofibers for Effective Diabetic Wound Healing: In-Vitro and In-Vivo Assessments
Published 2021-03-01“…LNFs were further characterized biologically by in-vitro assessment of their potency against <i>S. aureus</i> clinical strains (<i>N</i> = 16) using the Kirby–Bauer test and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, by <i>ex-vivo</i> assessment to evaluate their cytotoxicity against primary human epidermal keratinocytes using MTT assay, and by in-vivo assessment to estimate their diabetic chronic wound-healing efficiency using NcZ10 diabetic/obese mice (<i>N</i> = 18). …”
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21493
Photoreceptor metabolic window unveils eye–body interactions
Published 2025-01-01“…Our work, replicated across cohorts of diverse ethnicities, reveals the potential of photoreceptors to inform systemic health and advance a multisystem perspective on human health by revealing eye–body connections and shared metabolic influences.…”
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21494
Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis
Published 2024-12-01“…Functional analysis revealed rs610261’s regulatory potential, with the protective A allele correlating with increased <i>DENND2D</i> expression in various human tissues. Compared to normal prostate tissues, <i>DENND2D</i> expression was reduced in prostate cancer, with higher expression being linked to favorable patient prognosis (<i>p</i> = 0.03). …”
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21496
Predicting the risk of high-grade precancerous cervical lesions based on high-risk HPV typing in Changsha China
Published 2025-01-01“…Abstract Background Persistent infection with high-risk human papillomavirus (HPV) is a significant risk factor for cervical cancer. …”
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21497
Chronic NaAsO2 exposure promotes migration and invasion of prostate cancer cells by Akt/GSK-3β/β-catenin/TCF4 axis-mediated epithelial-mesenchymal transition
Published 2025-01-01“…Inorganic arsenic is a Class I human Carcinogen. However, the role of chronic inorganic arsenic exposure on prostate cancer metastasis still unclear. …”
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21498
Development of the Dutch translational knowledge agenda for inherited metabolic diseases
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21499
Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome
Published 2025-02-01“…Immunofluorescence assay was employed to measure the expression of p-eIF2α, ATF4 and CHOP in the ovarian tissue. After steroidogenic human granulosa-like tumor cell line KGN were exposed to 100 μmol/L DHEA to simulate the hyperandrogen environment of PCOS, and then treated with 5 and 10 μg/mL AS for 24 h, the protein levels of endoplasmic reticulum stress signaling pathway was detected by Western blotting. …”
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21500
Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin
Published 2011-01-01“…To contribute to the understanding of the molecular mechanisms underlying leptin action in breast cancer, our aim was to identify proteins regulated by leptin in MCF-7 human breast cancer cells. Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify proteins affected by leptin. …”
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