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21261
Impacts of meteorology and emission reductions on haze pollution during the lockdown in the North China Plain
Published 2025-02-01“…<p>Haze events in the North China Plain (NCP) during the COVID-19 lockdown underscore the intricate challenges of air quality management amid reduced human activities. Utilizing the WRF-Chem model, we explored how sharp emission reductions and varying meteorological conditions influenced fine-particulate-matter (PM<span class="inline-formula"><sub>2.5</sub></span>) concentrations across the NCP. …”
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21262
Magnitude of consistent condom use and associated factors among people living with HIV/AIDS in Ethiopia: Implication for reducing infections and re-infection. A systematic review a...
Published 2024-01-01“…<h4>Background</h4>The human immune virus or acquired immune deficiency syndrome, is a major threat to the health of millions of people worldwide. …”
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21263
Primary Clear Cell Adenocarcinoma of the Cervix: A Clinical Analysis of 18 Cases without Exposure to Diethylstilbestrol
Published 2019-01-01“…The most common type of lesion was the endocervical type (66.7%, 12/18). The negative rate of human papillomavirus (HPV) examination was 88.9% (8/9). …”
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21264
Design of a Cost-Effective Ultrasound Force Sensor and Force Control System for Robotic Extra-Body Ultrasound Imaging
Published 2025-01-01“…Robot-assisted ultrasound may provide a solution by delivering more consistent, precise, and faster scans, potentially reducing human error and healthcare costs. Effective force control is crucial in robotic ultrasound scanning to ensure consistent image quality and patient safety. …”
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21265
Autocrine Acetylcholine, Induced by IL-17A via NFκB and ERK1/2 Pathway Activation, Promotes MUC5AC and IL-8 Synthesis in Bronchial Epithelial Cells
Published 2016-01-01“…Bronchial epithelial cells were stimulated with recombinant human IL-17A (rhIL-17A) to evaluate the ChAT expression, the ACh binding and production, the IL-8 release, and the Muc5AC production. …”
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21266
Association Between Diurnal Temperature Range and Risk of Cardiomyopathy-Induced Hospitalisation in Henan, China: A Time-Series Study
Published 2025-01-01“…Zhaolin Zhang,1,* Yongbin Wang,2,* Yifeng Zhou,1 Jiachao Pei,1 Guoan Zhao,1,3 Pingshuan Dong,4 Kan Yang,5 Hui Liu,6 Na Xie,7 Xuefang Li,3 Xiayan Zang,3 Fei Lin,1,3 Zhigang Chen1 1Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 2Department of Epidemiology and Health Statistics, Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China; 3Henan Engineering Technology Research Center of Environmental Meteorological Medicine, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, People’s Republic of China; 4Department of Cardiology,The First Affiliated Hospital of Henan University of Science and Technology, Luoyan, 471000, People’s Republic of China; 5Department of Cardiology,Nanyang Central Hospital, Nanyang, 473005, People’s Republic of China; 6Department of Cardiology,Anyang District Hospital, Anyang, 455000, People’s Republic of China; 7Department of Cardiology,The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Lin; Zhigang Chen, Department of Cardiology,The First Affiliated Hospital of Xinxiang Medical University, No. 88 Jiankang Road, Weihui, Henan, People’s Republic of China, Tel +86 18567557937, Email 1fy2000129@xxmu.edu.cn; 1fy2015157@xxmu.edu.cnPurpose: The effect of the diurnal temperature range (DTR) on human health in diverse geographic areas and the potential confounding factors are not fully understood. …”
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21267
Multiview Multimodal Feature Fusion for Breast Cancer Classification Using Deep Learning
Published 2025-01-01“…Deep learning (DL) has shown superior diagnostic performance in breast cancer classification compared to human experts. However, most DL methods have relied on unimodal features, which may limit the performance of diagnostic models. …”
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21268
Stimulus-activated ribonuclease targeting chimeras for tumor microenvironment activated cancer therapy
Published 2025-02-01“…The degradation of pre-miR-21 by TaRiboTACs significantly increases the radiotherapeutic susceptibility of cancer cells achieving efficient suppression of human lung adenocarcinoma A549 tumors in living mice.…”
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21269
Synergistic antimicrobial activity of essential oils mixture of Moringa oleifera, Cinnamomum verum and Nigella sativa against Staphylococcus aureus using L-optimal mixture design
Published 2025-01-01“…Notably, the oil mixture of run 15 demonstrated excellent biocompatibility, maintaining 97.6% viability of normal human skin fibroblasts (HSF) after 24 h exposure to 200 μL EOs of the mixture per mL. …”
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21270
Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells
Published 2025-01-01“…<b>Background/Objectives</b>: Macrophages play a pivotal role in various pathogenic processes, necessitating the development of efficient differentiation techniques to meet the high demand for these cells in research and therapy. Human macrophages can be obtained via culturing peripheral blood monocytes; however, this source has limited yields and requires patient contact for each proposed use. …”
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21271
Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms
Published 2025-02-01“…Secondly, exploring microbiota biomarkers related to aging and discussing future possibility using dietary regime/components targeted to aging-related microbiota biomarkers promote human healthy lifespan. Thirdly, dietary intervention can effectively improve the imbalance of gut microbiota related to aging, such as probiotics, prebiotics, and postbiotics, but their effects vary among.…”
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21272
Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells
Published 2025-01-01“…Translating this approach to the human setting is achievable and will yield both critical insights into the fundamental basis of alloreactivity and powerful tools for immune monitoring in transplantation.…”
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21273
Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog
Published 2019-03-01“…Here, we showed the diagnostic and prognostic values of elevated Nr5a2 expression in human lung cancer. We generated the mouse LLC‐SD lung carcinoma CSC cellular model in which Nr5a2 expression was enhanced. …”
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21274
Quantification of antimicrobial use on Irish dairy farms: A comparison of three recording methods
Published 2025-02-01“…ABSTRACT: Antimicrobial use (AMU) data are essential for monitoring usage over time, facilitating reduction strategies to combat the threat of antimicrobial resistance (AMR) to both human and animal health. The objective of this study was to measure and describe AMU over a 12-mo period in Irish dairy herds and compare 3 different recording methods to a reference method. …”
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21275
Zero-Shot Remote Sensing Scene Classification Based on Automatic Knowledge Graph and Dual-Branch Semantic Correlation Supervision
Published 2025-01-01“…However, current graphs rely heavily on expert manual interpretation, making them susceptible to human biases and difficult to expand. They also lack quantitative description of the degree of spatial relationship associations and fail to adequately represent semantic information. …”
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21277
Bergapten alleviates senescence of chondrocytes in osteoarthritis
Published 2025-02-01“…The obtained targets were intersected with Venny2.1.0, protein-protein interaction (PPI) analysis was performed using the STRING database, and molecular docking was conducted by AutoDock Vina. Subsequently, human chondrocyte C28/I2 cells were subjected in the following validation experiments. …”
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21278
Pre-transplant T-cell clonal analysis identifies CD8+ donor reactive clones that contribute to kidney transplant rejection
Published 2025-02-01“…IntroductionResponses to allogeneic human leukocyte antigen (HLA) molecules limit the survival of transplanted organs. …”
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21279
Lateralization study of the basal ganglia, thalamus and supplying arteries in healthy individuals based on structure and connectivity analysis using 7.0T MRI
Published 2025-02-01“…The human cerebral cortex is known for its hemispheric specialization, which underpins a variety of functions and activities. …”
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21280
Preserving postharvest storage quality of fresh-cut cactus pears by using different bio-materials
Published 2020-07-01“…Miller) is an important food source for human beings but its consumption and marketability are limited due to the presence of spines and glochids on the fruit surface. …”
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