Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…The rising threat of antimicrobial resistance (AMR) is a global concern in both human and veterinary medicine, with multidrug-resistant (MDR) pathogens such as <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> presenting significant challenges. …”
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E. W. Godwin’s Month in Normandy: Travel Writing as Intertext by Richard W. Hayes

“…As would be expected of one of England’s prominent Gothic Revival architects, Godwin concentrated on the important examples of medieval architecture he encountered in what was a combined holiday and sketching tour. Nevertheless, a few human interest observations pepper his text, such as remarks on the cleanliness of provincial hotels and the quality of food and drink encountered. …”
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An extensive review on implantable antennas for biomedical applications: Health considerations, geometries, fabrication techniques, and challenges by Mosab Jasim, Ahmed Jamal Abdullah Al-Gburi, Mehwish Hanif, Zaheer Ahmed Dayo, Mohd Muzafar Ismail, Zahriladha Zakaria

“…Meeting these stringent standards is essential to ensure that IMDs operate safely and effectively within the human body over extended periods. By providing an in-depth review of state-of-the-art solutions and identifying emerging trends, this paper serves as an invaluable resource for researchers, engineers, and medical practitioners involved in the design and deployment of implantable medical devices. …”
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Impact of pulmonary yoga module on lung capacity of COVID-19 adult survivors by Adarsh Tomar, Sudhanshu Verma

“…BACKGROUND: Although every organ has its own importance in the human body, the significance of the lungs is vital. …”
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Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists by Christian Behm, Alice Blufstein, Johannes Gahn, Nazanin Noroozkhan, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

“…Human periodontal ligament stem cells (hPDLSCs) do not express membrane-bound CD14, and their responsiveness to bacterial lipopolysaccharide (LPS) is drastically enhanced by soluble CD14 (sCD14), which is due to the facilitation of the interaction between LPS and Toll-like receptor- (TLR-) 4. …”
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Concordance of Australian state and territory government guidelines for classifying the healthiness of foods in public settings by Bettina Backman, Meg Adam, Jasmine Chan, Josephine Marshall, Emalie Rosewarne, Gary Sacks, Adrian J Cameron, Miranda R Blake

“…Setting: Australia Participants: No human participants. Results: Approximately half (56%) of the 967 food and drink products assessed were classified as the same level of healthiness across all 15 ‘traffic light’-based systems. …”
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Targeting the activated allosteric conformation of the endothelin receptor B in melanoma with an antibody-drug conjugate: mechanisms and therapeutic efficacy by Amaury Herbet, Marie Hautière, Frédéric Jean-Alphonse, Delphine Vivier, Christophe Leboeuf, Narciso Costa, Aloïse Mabondzo, Guilhem Bousquet, Franck Denat, Eric Reiter, Didier Boquet

“…Methods We previously reported the rendomab B49 antibody (RB49) exhibiting a preferential affinity for the activated conformation of human endothelin B receptor (ETB), not displaced by high endothelin levels, and without any pharmacological properties that could inhibit the division of melanoma cells. …”
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Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro by Paulina Kobylka, Pawel Bakun, Joanna Kuzminska, Tomasz Goslinski, Marek Murias, Malgorzata Kucinska

“…This study tested curcumin derivatives with modified feruloyl moieties (<b>2a</b> and <b>2a-B</b>) and the β-diketo moiety (<b>2a-B</b>) to better understand their anticancer mechanism against human bladder cancer cells. The anticancer activity of <b>2a</b> and <b>2a-B</b> was determined using MTT (hypoxic conditions) and LDH (normoxic conditions) assays. …”
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Analysis of argument structure constructions in the large language model BERT by Pegah Ramezani, Pegah Ramezani, Achim Schilling, Achim Schilling, Patrick Krauss, Patrick Krauss

“…This research demonstrates the potential of both recurrent and transformer-based neural language models to mirror linguistic processing in the human brain, offering valuable insights into the computational and neural mechanisms underlying language understanding.…”
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Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments by Amit Verma, Vikas Pandey, Catherine Sherry, Taylor Humphrey, Christopher James, Kailie Matteson, Jason T. Smith, Alena Rudkouskaya, Xavier Intes, Margarida Barroso

“…Abstract Trastuzumab (TZM) is a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2) and is clinically used for the treatment of HER2‐positive breast tumors. …”
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Genetic diversity of VIR Raphanus sativus L. collections on aluminum tolerance by A. B. Kurina, I. A. Kosareva, A. M. Artemyeva

“…Radish and small radish (Raphanus sativus L.) are popular and widely cultivated root vegetables in the world, which occupy an important place in human nutrition. Edaphic stressors have a significant impact on their productivity and quality. …”
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Population Shrinkage and Spatio-Temporal Changes in Cultivated Land Use Efficiency in China’s Agro-Pastoral Ecotone by Lu Chen, Ning Zhao, Zhixun Zhang, Yun Zhang, Wenjie Zuo, Youshuo Wang, Bin Wu, Monika Stanny, Yuheng Li, Guoming Du

“…In this paper, using the stochastic frontier production function and a Tobit regression model, we reveal the current situation of rural population shrinkage in the agro-pastoral ecotone in northern China and the spatial and temporal evolution characteristics of cultivated land use efficiency, and identify influencing factors based on the perspective of “human–land”. The results show the following: (1) The rural population in all provinces and counties in the agro-pastoral ecotone in northern China showed a continuous loss trend. …”
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Protocol of the Nurses’ Mental Health Study (NMHS): a nationwide hospital multicentre prospective cohort study by Jiaxin Yang, Chongmei Huang, Shuiyuan Xiao, Xuting Li, Meng Ning, Zengyu Chen, Yusheng Tian, Qiang Yu, Yamin Chen, Ya-Min Li

“…Introduction Due to high workload, shift work and shortage of human resources, nurses are vulnerable to various mental health problems which are significantly related to their physical health, patient safety and healthcare quality. …”
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The Usefulness of the Pressure Algometer in the Diagnosis and Treatment of Orofacial Pain Patients: A Systematic Review by Agata Kamińska, Bartosz Dalewski, Ewa Sobolewska

“…The titles and abstracts from electronic search results were screened for keywords and evaluated by two observers, with the following inclusion criteria: published since 1997, written in English, and encompassing human research. Exclusion criteria were as follows: articles published earlier than 1997, not written in English, animal studies, studies with the use of medicaments, and articles examining receptor interactions. …”
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HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis by Erchen Zhang, Lei Peng, Kejia Yuan, Zexian Ding, Qi Yi

“…These results provide insights into the mechanism of ATRX's centromeric localization and its critical function in preserving centromeric cohesion by reducing Wapl activity in human cells.…”
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Testicular Cancer Presenting as Gastric Variceal Hemorrhage by Carlos Eduardo Salazar-Mejía, David Hernández-Barajas, Edio Llerena-Hernández, José Luis González-Vela, María Inés Contreras-Salcido, Adriana González-Gutiérrez, Omar David Borjas-Almaguer, Luis Alberto Pérez-Arredondo, Blanca Otilia Wimer-Castillo

“…The serum alpha-fetoprotein level was 17,090 ng/mL, lactate dehydrogenase was 1480 U/L, and human chorionic gonadotropin was 287.4 IU/mL. Upper endoscopy revealed a type 1 isolated gastric varix, treated with cyanoacrylate. …”
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Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for... by Jiyauddin Khan, Priyanjana Ghosh, Urmi Bajpai, Kountay Dwivedi, Daman Saluja

“…Validation of hub genes at mRNA and protein levels was done via GEPIA2 and Human Protein Atlas. Survival analysis was conducted using TCGA data by GEPIA2 and LASSO, and drug sensitivity was analyzed with the GSCA drug bank database, highlighting potential therapeutic targets. …”
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Evaluation of choices and time spent on an open online elective course by undergraduate medical students during the COVID-19 pandemic by Z Mfeka, A Turner, J E Wolvaardt, D Muganhiri

“…The most popular courses related to the Leader and Manager role were around decision-making in human resources, problem-solving, and managing healthcare teams. …”
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Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA by Jihane Oufattole, Anne Piantadosi, Sam R. Telford, Alvaro C. Laga, Isaac H. Solomon

“…ABSTRACT Ixodes scapularis is a vector of several human pathogens in the United States, including Borrelia burgdorferi, the cause of Lyme disease, and Powassan virus (POWV), an emerging cause of severe encephalitis. …”
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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

“…New in vitro binding data is also made available for (-)-FEOBV with human-sourced σ1 receptors, revealing a 300-fold stronger affinity for VAChT compared to σ receptors. …”
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