Water-Soluble Vitamins: Hypo- and Hypervitaminosis in Pediatric Population by Roberto Paparella, Fabiola Panvino, Lucia Leonardi, Ida Pucarelli, Michela Menghi, Ginevra Micangeli, Francesca Tarani, Marcello Niceta, Debora Rasio, Rouzha Pancheva, Marco Fiore, Luigi Tarani

Get full text

Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

“…Previous studies demonstrated that both recombinant mice and human IL-35 attenuated atherosclerosis in ApoE-/- mice. …”
Get full text

Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction by Mohsen Moslem, Irina Eberle, Iuliia Weber, Reinhard Henschler, Tobias Cantz

“…Here, we investigated a differentiation protocol enabling the generation and selection of human iPSC-derived MSCs exhibiting relevant surface marker expression profiles (CD105 and CD73) and functional characteristics. …”
Get full text

The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001 by Kejian Tian, Fanxing Meng, Qi Meng, Yan Gao, Lili Zhang, Le Wang, Yuqing Wang, Xue Li, Hongliang Huo

“…Environmental estrogens are mainly derived from human and vertebrate excretion, drugs, and agricultural activities. …”
Get full text

Facile Synthesis, Characterization, and Cytotoxic Activity of Europium-Doped Nanohydroxyapatite by Paulina-Guadalupe Miranda-Meléndez, Gabriel-Alejandro Martínez-Castañón, Nereyda Niño-Martínez, Nuria Patiño-Marín, Miguel-Ángel Casillas-Santana, Brenda-Erendida Castillo-Silva, Facundo Ruiz

“…The toxicity effects of all samples were studied using viability assays on human fibroblasts cells (HGF-1) in vitro. The sizes of the crystallites were about 10–70 nm with irregular morphology and present the phase corresponding to the JCPDS card 9–0432 for hydroxyapatite. …”
Get full text

Climate change as a wildlife health threat: a scoping review by Sabrina S. Greening, Lucie R. Pascarosa, Avery L. Munster, Roderick B. Gagne, Julie C. Ellis

“…Amongst the subset of papers focused on vector distribution, top themes included concepts related to pathogen transmission dynamics, human/public health, and pathogen prevalence, while health papers focused on concepts related to increasing temperatures, species home ranges and distribution, and changing environmental variables. …”
Get full text

Anti-Inflammatory Potentials of β-Ketoester Derivatives of N-Ary Succinimides: In Vitro, In Vivo, and Molecular Docking Studies by Yahya S. Alqahtani, Muhammad Saeed Jan, Mater H. Mahnashi, Bandar A. Alyami, Ali O. Alqarni, Umer Rashid, Fawad Mahmood, Muhammad Tariq, Abdul Sadiq

“…Inflammation, being a well-known and complex pathological condition, is always a challenge to the human health. This research work was designed for a rationale-based anti-inflammatory study on β-ketoester derivatives of N-ary succinimides. …”
Get full text

Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita by Sana Alam, Gulnaz Afzal, Riaz Hussain, Hafiz Muhammad Ali, Amtul Sami, Rabbiah Manzoor Malik, Raheela Jabeen, Farid Shokry Ataya, Kun Li

“…The findings demonstrate that thiram severely pollute the marine eco-system and is quite hazardous for aquatic species by causing severe health effects even at sub-lethal concentrations and thus, render the apparently clean water to be unfit for animal and human consumption.…”
Get full text

Chronic and infectious respiratory mortality and short-term exposures to four types of pollen taxa in older adults in Michigan, 2006-2017 by Peter S. Larson, Allison L. Steiner, Marie S. O’Neill, Alan P. Baptist, Carina J. Gronlund

“…Methods We obtained records for all Michigan deaths from 2006-2017 from the Michigan Department of Health and Human Services (MDHHS). Deaths from infectious and chronic respiratory-related causes were selected using International Classification of Diseases (ICD-10) codes. …”
Get full text

Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes by Yukiko Kikuchi, Mohammed Uddin, Joris A. Veltman, Sara Wells, Christopher Morris, Marc Woodbury-Smith

“…Rhesus macaques (Macaca mulatta) have been extensively used for preclinical neurobiological research because of remarkable similarities to humans across biology and behaviour that cannot be captured by other experimental animals. …”
Get full text

Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon by Ornella J. T. Ngalani, Armelle T. Mbaveng, Wiliane J. T. Marbou, Roland Y. Ngai, Victor Kuete

“…Human immunodeficiency virus (HIV) infection is a serious problem throughout the world and especially in developing countries. …”
Get full text

Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach by Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli

“…The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. …”
Get full text

BTS1-knockout Saccharomyces cerevisiae with broad-spectrum antimicrobial activity through lactic acid accumulation by Liu Cong, Yuan Zhou, Yu Zhang, Shanshan Mao, Chaoqun Chen, Liying Wang, Xiao Li, Zuo Zhang, Zuobin Zhu, Ying Li

“…Bacterial infections pose significant threats to human health, and prudent antibiotic use remains a key strategy for disease treatment and control. …”
Get full text

Combatting Salmonella: a focus on antimicrobial resistance and the need for effective vaccination by Junaid Nazir, Tasaduq Manzoor, Afnan Saleem, Ubaid Gani, Sahar Saleem Bhat, Shabir Khan, Zulfqarul Haq, Priyanka Jha, Syed Mudasir Ahmad

“…Typhimurium were the most prevalent serovars associated with human infections. The review highlighted an alarming rise in multidrug-resistant (MDR) Salmonella strains, particularly due to the overuse of antibiotics in humans and livestock. …”
Get full text

Use of alternative payment models for substance use disorder prevention in the United States: development of a conceptual framework by Elian Rosenfeld, Sarah Potter, Jennifer Caputo, Sushmita Shoma Ghose, Nelia Nadal, Christopher M. Jones, Margaret R. Kuklinski, Andrew D. Carlo, D. Max Crowley, Lisa Clemans-Cope, Michael T. French

Get full text

Real-World Assessment of Weight Change in People with HIV-1 After Initiating Integrase Strand Transfer Inhibitors or Protease Inhibitors by Yen-Wen Chen, Helene Hardy, Christopher D. Pericone, Wing Chow

“…**Background:** Studies have shown an increase in weight among people living with human immunodeficiency virus (PLWH) who have also initiated integrase strand transfer inhibitors (INSTI). …”
Get full text

Immunogenicity of HIV-1 <i>Env</i> mRNA and <i>Env-Gag</i> VLP mRNA Vaccines in Mice by Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng

“…Background: The development of a protective vaccine is critical for conclusively ending the human immunodeficiency virus (HIV) epidemic. Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins. …”
Get full text

Cultural humility strategies for recruitment and retention of minoritised participants: a scoping review protocol by Mireille Chehade, Kellie McLean, Samar Mohsen Ashmawi, Moroni Fernandez Cajavilca, Baomi T Phung, Maya N Clark-Cutaia, Brynne Campbell Rice

Get full text

Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Alkaline phosphatase (ALP) is a ubiquitously expressed dephosphorylating enzyme and its level in blood is widely used as a diagnosis marker of liver damage or bone disorders in human patients. ALP is also considered as an anti-inflammatory protein due to its ability to dephosphorylate and inactivate inflammation-triggering molecules such as lipopolysaccharide (LPS). …”
Get full text

Geochemistry and mineralogy of Cobalt in mine wastes: examples from Cobalt, Canada and Cornwall, England by Gabriel Ziwa, Gabriel Ziwa, Gabriel Ziwa, Rich Crane, Rich Crane, Karen A. Hudson-Edwards, Karen A. Hudson-Edwards

“…Mine wastes can pose environmental and human health risks, especially when they contain high concentrations of potentially toxic metal(loid)s. …”
Get full text