Enhancing postharvest quality of bananas: comparative study on the use ZnO and Ag2O nanoparticles and ZnO/Ag2O composites by Noluthando Noxolo Aruwajoye, Isaac Adeyemi Sanusi, Gabriel Sanjo Aruwajoye, Asanda Mditshwa, Samson Zeray Tesfay

Get full text

Inactivation of Escherichia coli O157:H7 in Dairy Manure Compost with Alkaline Walnut Hull Biochar by Joshua B. Gurtler, Charles A. Mullen

“…., Salmonella enterica, Campylobacter jejuni, and Listeria monocytogenes), with the goal of reducing the dissemination of human bacterial pathogens to meat, poultry, and fresh produce.…”
Get full text

Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis by Lina He, Jie Lin, Zhengwen Qin, Qing Xu, Li Hao, Yanhong Fu, Xu Ran, Wei Chen

“…Methods We investigated the function of lncRNA NEAT1 in human ovarian granulosa-like tumor cells (KGN). The effects of NEAT1 overexpression or silencing on cell proliferation and cell cycle were evaluated using CCK-8 assays and flow cytometry. …”
Get full text

Strategies for H-score Normalization of Preanalytical Technical Variables with Potential Utility to Immunohistochemical-Based Biomarker Quantitation in Therapeutic Reponse Diagnost... by William E. Pierceall, Michele Wolfe, Jessica Suschak, Hua Chang, Yan Chen, Kam M. Sprott, Jeffery L. Kutok, Stella Quan, David T. Weaver, Brian E. Ward

“…To examine the effects of preanalytical fixation variation on biomarker quantitation and potential utility of candidate calibrators to address such issues, 6 surgically-resected human breast cancer patient specimens were divided into 6 portions and fixed under distinct conditions (fixation following resection in formalin for 2 hr, 8 hr or 48 hr, or held overnight at 4°C in buffered saline prior to formalin fixation for 2 hr, 8 hr, or 48 hr). …”
Get full text

Nerve‐Inspired Optical Waveguide Stretchable Sensor Fusing Wireless Transmission and AI Enabling Smart Tele‐Healthcare by Tianliang Li, Qian'ao Wang, Zichun Cao, Jianglin Zhu, Nian Wang, Run Li, Wei Meng, Quan Liu, Shifan Yu, Xinqin Liao, Aiguo Song, Yuegang Tan, Zude Zhou

“…A speech recognition and human‐machine interaction system, based on sensor signal acquisition, is constructed, and the convolutional neural network algorithm is integrated for disease assessment. …”
Get full text

The Link between Overweight/Obesity and Noncommunicable Diseases in Ethiopia: Evidences from Nationwide WHO STEPS Survey 2015 by Bedilu Alamirie Ejigu, Fentanesh Nibret Tiruneh

Get full text

ENERGY AND ECONOMIC EFFICIENCY OF BIOETHANOL PRODUCTION DEPENDING ON THE QUALITY OF CORN GRAIN by Vitalii Palamarchuk, Roman Lohosha, Vadim Krychkovskyi

“…It has been established that the production of bioethanol from maize grain is an innovative technology: it improves the ecological situation and reduces harmful effects on the human body and the environment. The use of maize as a raw material partially resolves the existing conflict of interest associated with the use of food resources for bioethanol production. …”
Get full text

Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy by Patrizia Murer, Barbara Brannetti, Jean-Michel Rondeau, Laetitia Petersen, Nicole Egli, Simone Popp, Catherine Regnier, Kirsten Richter, Andreas Katopodis, Christoph Huber

“…Novel engineered IL-2 agonists strive to increase the therapeutic window of aldesleukin (human IL-2) by increasing selectivity toward effector over regulatory T cells and reducing dose-limiting toxicities. …”
Get full text

β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy by Yihui Huo, Taiyu Shen, Tianyin Feng, Moli Li, Wanli Zhao, Juan J. Loor, Ben Aernouts, Androniki Psifidi, Chuang Xu

Get full text

Bioaccumulation and Health Risk Assessments of Heavy Metals in Mussels Collected from Madura Strait, Indonesia by Defri Yona, Aida Sartimbul, Muhammad Arif Rahman, Syarifah Hikmah Julinda Sari, Priyanka Mondal, Abdullah Hamid, Tsania Humairoh

“…The Estimated Daily Intake (EDI) of the marine mussels was lower than the oral reference dose (ORD) and low values of target hazard quotient (THQ < 1) had shown that the consumption of mussels containing heavy metals would not cause significant health risks to humans. The health risk assessment indexes showed low values, which meant insignificant health hazard. …”
Get full text

The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability by Emily Graham, Lucia Rampazzo, Chin Wei Brian Leung, Jacob Wall, Emőke Zsanett Gerőcz, Mikhail Liskovykh, Nikolay Goncharov, Xanita Saayman, Ramazan Gundogdu, Masato T. Kanemaki, Hiroshi Masumoto, Vladimir Larionov, Natalay Kouprina, Fumiko Esashi

“…We find that BRCA2, but not PALB2, is essential for maintaining a human artificial chromosome. In native chromosomes, BRCA2 ensures CENP-A occupancy and prevents DNA fragility at centromeres. …”
Get full text

Analysis of factors influencing HPV vaccination intention among Chinese college students: structural equation modeling based on health belief theory by Shi-Yuan Song, Ying Guo, Yi-Hua Li, Zheng Wang, Wei Gao

“…BackgroundIncreasing human papillomavirus (HPV) vaccination rates is vital for achieving society-wide public health goals, yet current research on HPV vaccine-related knowledge, vaccination intentions, and behaviors among college students in ethnic minority regions is inadequate. …”
Get full text

Characterization of demethylating DNA glycosylase ROS1 from Nicotiana tabacum L. by D. V. Petrova, N. V. Permyakova, I. R. Grin, D. O. Zharkov

“…Expression of the NtROS1 gene in cultured human cells resulted in a global decrease in the level of genomic DNA methylation. …”
Get full text

Geomatics and metaverse for lost heritage sites documentation and dissemination: the case study of Palmyra Roman Theatre (Syria) by Anna Forte, Yara Jamil Alkhatib, Gabriele Bitelli, Eva Savina Malinverni, Roberto Pierdicca

“…Unfortunately, in addition to natural and environmental degradation, human activities pose a significant threat to the integrity of historical sites. …”
Get full text

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…During conducting a first-in-human trial for a new molecular entity, we were able to determine the mechanism of dichotomized variability in plasma drug concentrations, which appeared closely related to adverse drug reactions (ADRs) through integrated omics analysis. …”
Get full text

Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer by Liping Luo, Juan Ji, Juan Dong, Maotao He, Wenjun Jiang, Yang Liu, Weidong Wang

“…Abstract Background CD3 + CD20 + T cells (TB cells) are a subset of lymphocytes in the human body that are associated with inflammation. …”
Get full text

An in vitro study on comparative evaluation of shear bond strength of bioactive composite to tooth structure with various dentin conditioning agents by Priyanka Pokkula, Shaik Mohammed Asif, Abdullah Alqarni, Shahabe Saquib Abullais, Shaik Mohamed Shamsudeen, Syed M Yassin, Abosofyan S. Atta, Wahaj Ahmad Khan

“…This study uses various bonding and conditioning agents to evaluate the strength of bioactive composite shear bonds to the tooth structure. Sixty extracted human maxillary premolars were collected for this study. …”
Get full text

Identification of antibiotic use patterns in poultry farms in the southwest region of Bangladesh by Sarder Safiqul Islam, Ratna Ghosh, Md. Shafiqul Islam, Minhazul Abedin Sun, Mustajabur Rahman, Dhiman Mondol

“…The majority of the farmers did not know about the negative impacts of antibiotic use in poultry farming (87.8%), among the remaining 7.8% of farmers said it was carcinogenic, 3.3% stated it was toxicity in humans and only 1.1% said it had no effect of antibiotics in human health. …”
Get full text

Streptococcus suis-associated neonatal meningitis and sepsis: characterization, antimicrobial resistance, and public health implications by Giovanna Fusco, Rubina Paradiso, Lorena Cardillo, Maria Antonia Salvia, Saveria Dodaro, Veronica Del Monaco, Gianfranco Scarpelli, Francesca Greco, Antonio Rinaldi, Lorella Barca, Stefania Ambrogio, Antonio Limone, Esterina De Carlo, Giorgia Borriello

“…High homology was observed with previously identified human and swine strains in the same area. S. suis meningitis and sepsis are mainly reported in adults, related to direct contact with pigs or contaminated pork meat consumption, while it is rarely reported in children. …”
Get full text

Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. Their detection and analysis are particularly challenging, necessitating advanced analytical techniques to support regulatory measures and ensure safe drinking water. …”
Get full text