Photodynamic Therapy with the Silicon Phthalocyanine Pc 4 Induces Apoptosis in Mycosis Fungoides and Sezary Syndrome by Minh Lam, YooJin Lee, Min Deng, Andrew H. Hsia, Kelly A. Morrissey, Chunlin Yan, Kashif Azzizudin, Nancy L. Oleinick, Thomas S. McCormick, Kevin D. Cooper, Elma D. Baron

“…Our current focus on the effects of Photodynamic Therapy (PDT) using silicon phthalocyanine Pc 4 photosensitizer on malignant T lymphocytes arose due to preclinical observations that Jurkat cells, common surrogate for human T cell lymphoma, were more sensitive to Pc 4-PDT-induced killing than epidermoid carcinoma A431 cells. …”
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Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo by Pengyue You, Di Wang, Zheng Liu, Shuzhen Guan, Ning Xiao, Haotian Chen, Xin Zhang, Lichuan Wu, Guizhen Wang, Haitao Dong

“…Replication factor C subunit 4 (RFC4), an oncogene active in various human cancers, has been rarely studied in OSCC. In the present study, bioinformatics analysis identified RFC4 as a potential key target in OSCC progression. …”
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Phlorofucofuroeckol-A: A Natural Compound with Potential to Attenuate Inflammatory Diseases Caused by Airborne Fine Dust by Eun-Gyeong Lee, Sung-Kun Yim, Sang-Min Kang, Byung Jae Ahn, Chang-Kwon Kim, Mina Lee, Dongseob Tark, Gun-Hee Lee

“…<i>Background and Objectives</i>: Persistent exposure to airborne fine dust (FD) particles contributing to air pollution has been linked to various human health issues, including respiratory inflammation, allergies, and skin diseases. …”
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The nature of self-medication in Uganda: a systematic review and meta-analysis by Danladi Makeri, Priscilla Peter Dilli, Theophilus Pius, Naheem Adekilekun Tijani, Abdullateef Afolabi Opeyemi, Kadai Alhaji Lawan, Shango Patience Emmanuel Jakheng, Reagan Muhwezi, Ambrose Shabohurira, Ibe Michael Usman, Ezera Agwu

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Sub-seasonal Patterns of PM10 and Black Carbon in a Coastal City: A Case Study of Salé, Morocco by Anas Otmani, Abdeslam Lachhab, Abdelfettah Benchrif, Mounia Tahri, Mohamed Azougagh, Mohammed El Bouch, El Mahjoub Chakir

“…Seasonal variations, wind patterns, and human activities affect air quality. Mitigating traffic emissions and promoting alternative energy sources can improve air quality in Salé. …”
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Organisational, legal and financial bases for scientific activity in higher education institutions of the Ministry of Internal Affairs of Ukraine: problems and solutions based on m... by S. O. Serbenyuk, L. S. Nadopta

“…The ideas and proposals for the introduction of new organisational and legal frameworks for scientific research in the system of the Ministry of Internal Affairs of Ukraine are an attempt to introduce a practical mechanism for the rational and most productive use of the scientific potential of departmental institutions and establishments to ensure the security of the State, protection of human rights and freedoms, combating crime, maintaining public safety and order, applying positive foreign experience in these areas, as well as the creation of innovative methods and technologies that can compete with similar achievements in the international scientific space.…”
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<i>In Silico</i> Investigation of γ-Sitosterol Isolated from the Ethanol Extract of <i>Artocarpus camansi</i> Leaves as a Sunscreen Agent by Rosnani Nasution, Rafna Azura, Muhammad Bahi, Nur Balqis Maulydia, Reza Akbar Bastian, Michelia Mutiara Hilda, Marianne Marianne

“…From the molecular docking, it is known that γ-sitosterol has the highest binding affinity value of −7.4 and −8.2 kcal/mol to human neutrophile collagenase (PDB ID: 1BZS) and fibroblast collagenase-1 (PDB ID: 966C), respectively. …”
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Practice and effectiveness evaluation of integrated teaching of life education and hospice & palliative care for undergraduates in a medical college in Shanghai by JING Limei, WANG Jingrong, WANG Hui

“…ObjectiveLife education and hospice & palliative care (HPC) involve many aspects of medicine, humanities and education, which is not only an important public health issue, but also an important livelihood issue and education issue widely concerned at home and abroad. …”
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Perancangan Katalog Digital untuk Representasi Stasiun Lokal Bandung Raya Melalui Fotografi Jalanan Monokromatik by Diaz Nafi, Maya Purnamasari, Saripudin Saripudin

“…Street photography is selected as the approach due to its ability to capture the dynamic and ever-changing human activities. The research employs a descriptive qualitative method, gathering data from street photography literature, monochromatic works, and direct field observations. …”
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Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype. by Florence E McLean, Brian R Omondi, Nouhoum Diallo, Stanley Otoboh, Carolyne Kifude, Abdirahman I Abdi, Rivka Lim, Thomas D Otto, Ashfaq Ghumra, J Alexandra Rowe

“…Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a diverse family of variant surface antigens, encoded by var genes, that mediates binding of infected erythrocytes to human cells and plays a key role in parasite immune evasion and malaria pathology. …”
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Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice by Alexandra F. Putka, Varshasnata Mohanty, Stephanie M. Cologna, Hayley S. McLoughlin

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Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes by Bing-rong Zhou, Jia-an Zhang, Qian Zhang, Felicia Permatasari, Yang Xu, Di Wu, Zhi-qiang Yin, Dan Luo

“…Pyrrolidine dithiocarbamate (PDTC, a selective chemical inhibitor of NF-κB) and goat anti-human IL-6 polyclonal neutralizing antibody were used to inhibit NF-κB activation and IL-6 production, respectively. …”
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Advancing Horticultural Crop Loss Reduction Through Robotic and AI Technologies: Innovations, Applications, and Practical Implications by H. W. Gammanpila, M. A. Nethmini Sashika, S. V. G. N. Priyadarshani

“…By reducing the reliance on human labor and enhancing operational efficiency, the integration of robotic solutions contribute to the minimization of crop losses and the augmentation of yields. …”
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Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries by Yi-Ping Zhong, Ying Ying, Hai-Tao Wu, Can-Quan Zhou, Yan-Wen Xu, Qiong Wang, Jie Li, Xiao-Ting Shen, Jin Li

“…The ovulatory PCO and PCOS patients showed similar levels of E2 on the human chorionic gonadotropin treatment day and numbers of oocytes, which were both significantly higher than those of the NO patients. …”
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Anterior Cruciate Ligament Mechanical Response to Load in the Setting of Changes to the Medial Meniscus by Angela Hussain, Muffaddal Madraswala, Jason Koh, Farid Amirouche

“…<b>Method</b>: Seven freshly frozen human cadaveric knees were used in a study to investigate the effects of different meniscal conditions and surgical interventions on the meniscus itself. …”
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Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder by Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan

“…We used functional connectome gradient (FCG) to capture the macroscopic hierarchical organization of human brain. Canonical correlation analysis was employed to identify components mapping relationships between FCG and behavioral scores. …”
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Assembly of soil multitrophic community regulates multifunctionality via multifaceted biotic factors in subtropical ecosystems by Chao Chang, En Hu, Xiaofeng Tang, Sisi Ye, Dan Zhao, Zhi Qu, Ming Li

“…Soil biodiversity underpins multiple ecosystem functions and services essential for human well-being. Understanding the determinants of biodiversity-ecosystem function relationships (BEFr) is critical for the conservation and management of soil ecosystems. …”
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Zingiber striolatum phytochemicals ameliorated hyperglycemia symptoms by modulating gut microbial communities in mice with type 2 diabetes mellitus by Tingting Liu, Xiaodong Ge, Lu Song, Huanhuan Wu, Xue Qian, Bowen Jia, Chao Zhao, Yi Zhuang

“…IntroductionProlonged hyperglycemia caused by type 2 diabetes mellitus (T2DM) can lead to liver injury and disrupt the community of the gut microbiota that pose significant risks to human health. As a food rich in a variety of active ingredients, Zingiber striolatum (Z. striolatum) exhibits hypoglycemic and hypolipidemic effects. …”
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Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material by Hisao Haniu, Naoto Saito, Yoshikazu Matsuda, Yuki Usui, Kaoru Aoki, Masayuki Shimizu, Nobuhide Ogihara, Kazuo Hara, Seiji Takanashi, Masanori Okamoto, Koichi Nakamura, Norio Ishigaki, Tamotsu Tsukahara, Hiroyuki Kato

“…We investigated the relationship between differences in multiwalled carbon nanotubes (MWCNTs) and the biological responses they elicit in order to develop biocompatible MWCNTs. We exposed human bronchial epithelial (BEAS-2B) cells to two sizes and six grades of MWCNTs and measured the resulting cell viability, total reactive oxygen and/or nitrogen species (tROS/RNS) production, and cytokine secretion. …”
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H3K4 methylation regulates development, DNA repair, and virulence in Mucorales by Macario Osorio-Concepción, Carlos Lax, Damaris Lorenzo-Gutiérrez, José Tomás Cánovas-Márquez, Ghizlane Tahiri, Eusebio Navarro, Ulrike Binder, Francisco Esteban Nicolás, Victoriano Garre

“…Abstract Mucorales are basal fungi that opportunistically cause a potentially fatal infection known as mucormycosis (black fungus disease), which poses a significant threat to human health due to its high mortality rate and its recent association with SARS-CoV-2 infections. …”
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