Showing 20,461 - 20,480 results of 25,478 for search '"human"', query time: 0.13s Refine Results
  1. 20461
  2. 20462
  3. 20463

    Increased SOAT2 expression in aged regulatory T cells is associated with altered cholesterol metabolism and reduced anti-tumor immunity by Mingjiong Zhang, Jiahua Cui, Haoyan Chen, Yifan Cheng, Qiaoyu Chen, Feng Zong, Xiao Lu, Lang Qin, Yu Han, Xingwang Kuai, Yuxing Zhang, Minjie Chu, Shuangshuang Wu, Jianqing Wu

    Published 2025-01-01
    “…Mechanically, ex vivo human and mouse Treg cell data and in vivo mouse tumor models suggest that SOAT2 overexpression in Treg cells promotes cholesterol metabolism by activating the SREBP2-HMGCR-GGPP pathway, leading to enhanced Treg suppresser functions but reduced CD8+ T cell proliferation, migration, homeostasis and anti-tumor immunity. …”
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  4. 20464
  5. 20465

    Tumour DNA methylation markers associated with breast cancer survival: a replication study by Elaheh Zarean, Shuai Li, Ee Ming Wong, Enes Makalic, Roger L. Milne, Graham G. Giles, Catriona McLean, Melissa C. Southey, Pierre-Antoine Dugué

    Published 2025-01-01
    “…Candidate methylation sites (N = 22) and signatures (N = 3) potentially associated with breast cancer survival were identified from five prior studies that used The Cancer Genome Atlas (TCGA) methylation dataset, which shares key characteristics with the MCCS: comparable sample size, tissue type (formalin-fixed paraffin-embedded; FFPE), technology (Illumina HumanMethylation450 array), and participant characteristics (age, ancestry, and disease subtype and severity). …”
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  6. 20466
  7. 20467

    Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens by Jie Zhang, Anna Li, Chang-qing Yang, Peter Garred, Ying Jie Ma

    Published 2019-01-01
    “…Furthermore, CL-12 has been shown to be associated with the pathogenesis of human diseases such as Alzheimer’s disease and multiple sclerosis lesion development. …”
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  8. 20468

    Quality of Life Philosophy IV. The Brain and Consciousness by Søren Ventegodt, Niels Jørgen Andersen, Joav Merrick

    Published 2003-01-01
    “…The connectivity seems to imply that the patterns of the human brain are 1000-dimensional. It is our vision that these complicated patterns arise from basic patterns in the quantum matter of which everything is created. …”
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  9. 20469

    Cell-free DNA release following psychosocial and physical stress in women and men by A. S. Limberg, F. Berg, E. Köper, C. Lindgraf, C. Gevers, R. Kumsta, E. M. Hummel, D. A. Moser

    Published 2025-01-01
    “…To overcome this, a multiplex quantitative polymerase chain reaction (qPCR) protocol targeting L1PA2 elements, which are prevalent in the human genome, was utilized. The analysis indicated significantly elevated levels of cf-nDNA in both plasma and saliva in all participants, irrespective of gender, following psychosocial and physical stress. …”
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  10. 20470

    The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin by Jin Zeng, Fuyang Song, Yi Yang, Chenjie Ma, Guangcun Deng, Yong Li, Yujiong Wang, Xiaoming Liu

    Published 2016-01-01
    “…Clostridium perfringens (C. perfringens) beta2 toxin (CPB2) is an important virulent factor of necrotic enteritis in both animals and humans. However, studies of its pathogenic roles and functional mechanisms have been hampered due to the difficulty of purification and lack of specific antibodies against this toxin. …”
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  11. 20471

    Physical, chemical and biological properties of MTA Angelus and novel AGM MTA: an in vitro analysis by Sara Nashibi, Parisa Amdjadi, SeyedehSana Ahmadi, Sara Hekmatian, Maryam Torshabi

    Published 2025-01-01
    “…Moreover, the cytotoxicity was assessed through the MTT assay on human dental pulp stem cells (hDPSCs) after 24 and 72 h of exposure to the set/fresh status of various dilutions of MTA extracts, following the ISO 10993-12 standard. …”
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  12. 20472

    Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer by Yugang Wu, Min Jin, Huanbai Xu, Zhang Shimin, Songbing He, Liang Wang, Yanyun Zhang

    Published 2010-01-01
    “…We investigated the clinicopathologic significance of HIF-1, CXCR4, and VEGF expression using immumohistochemistry in human colon cancer. HIF-1, CXCR4, and VEGF high expression levels were correlated positively with TNM stage, lymph node involvement, and distant metastasis Furthermore, we found that combined high expression of any two of the three molecules (P=.028 for HIF-1/CXCR4, P=.007 for HIF-1/VEGF, and P=.004 for CXCR4/VEGF) had stronger correlation with lymph node metastasis than did each alone. …”
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  13. 20473

    The microbial mechanism of maize residue decomposition under different temperature and moisture regimes in a Solonchak by Fan Huang, Wan Zhang, Lihua Xue, Bahar Razavi, Kazem Zamanian, Xiaoning Zhao

    Published 2025-01-01
    “…Abstract Soil salinization becomes serious under climate change and human activities. Although the residue decomposition contributes lots to soil carbon storage and fertility, the decomposition process and microbial mechanisms on saline-alkali soils are still vague facing climate change. …”
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  14. 20474

    Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family by Virginia J. Savin, Mukut Sharma, Jianping Zhou, David Gennochi, Timothy Fields, Ram Sharma, Ellen T. McCarthy, Tarak Srivastava, Jos Domen, Aurélie Tormo, Jean-François Gauchat

    Published 2015-01-01
    “…We have identified CLCF-1 as a potential injurious factor in the human renal disease focal segmental glomerulosclerosis (FSGS). …”
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  15. 20475

    Parent-of-origin effects on nuclear chromatin organization and behavior in a Drosophila model for Williams–Beuren Syndrome by A. V. Medvedeva, E. V. Tokmatcheva, A. N. Kaminskaya, S. A. Vasileva, E. A. Nikitina, A. V. Zhuravlev, G. A. Zakharov, O. G. Zatsepina, E. V. Savvateeva-Popova

    Published 2021-09-01
    “…Simple experimental model systems such as Drosophila help probe the causes and consequences leading to human neurocognitive pathologies. Recently, we have developed a Drosophila model for Williams–Beuren Syndrome (WBS): a mutant agnts3 of the agnostic locus (X:11AB) harboring the dlimk1 gene. …”
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  16. 20476

    MiMeJF: Application of Coupled Matrix and Tensor Factorization (CMTF) for Enhanced Microbiome-Metabolome Multi-Omic Analysis by Zheyuan Ou, Xi Fu, Dan Norbäck, Ruqin Lin, Jikai Wen, Yu Sun

    Published 2025-01-01
    “…Validation was conducted using three diverse microbiome/metabolome datasets, including built environments and human gut samples from inflammatory bowel disease (IBD) and COVID-19 studies. …”
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  17. 20477

    Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115 by Behrooz Alizadeh Behbahani, Mostafa Rahmati-Joneidabad, Morteza Taki

    Published 2025-06-01
    “…Probiotic bacteria improve human health by secreting pro-microbial substances, balancing intestinal flora, binding to the mucous membrane and epithelium, strengthening the intestinal epithelial barrier, and creating interactions between the gastrointestinal microbiota and the immune system. …”
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  18. 20478

    Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development by Corina Toma, Roxana Popa, Lidia Ciobanu, Ioana Baldea, Irina Amorim, Diana Bochynska, Alan Wolfe, Andrada Negoescu, Claudiu Gal, Marian Taulescu

    Published 2025-01-01
    “…Abstract Background Ovine pulmonary adenocarcinoma (OPA) is caused by Jaagsiekte sheep retrovirus (JSRV) and is considered an important potential animal model for human lung cancer. The precise mechanisms of OPA oncogenesis are still uncertain. …”
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  19. 20479
  20. 20480

    Occurrence of Enteric Viruses in Surface Water and the Relationship with Changes in Season and Physical Water Quality Dynamics by Wasonga Michael Opere, Maingi John, Omwoyo Ombori

    Published 2020-01-01
    “…Enteric viruses can affect both human and animal’s health by causing diseases such as gastrointestinal and respiratory infections. …”
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