Management of Oro-Antral Communication: A Systemic Review of Diagnostic and Therapeutic Strategies by Gianna Dipalma, Angelo Michele Inchingolo, Irma Trilli, Laura Ferrante, Angela Di Noia, Elisabetta de Ruvo, Francesco Inchingolo, Antonio Mancini, Stefan Cocis, Andrea Palermo, Alessio Danilo Inchingolo

“…Using targeted keywords, articles in English published within the last 10 years were analyzed from databases such as PubMed, WoS and Scopus, selecting only clinical studies on human patients. After thorough screening, 20 publications were included in the qualitative analysis, among 734 initially identified. …”
Get full text

Seasonal Variations and Health Risk Evaluation of Trace Elements in Atmospheric PM_2.5 in Liaocheng, the North China Plain by Yanhui Wang, Zhanfang Hou, Jiangkai Ma, Xiaoting Zhang, Xuan Liu, Qizong Wang, Chen Chen, Kaiyue Yang, Jingjing Meng

“…Atmospheric elements can cause harmful effects on air quality and human health. Despite extensive research on PM_2.5, there remains a limited understanding of the seasonal variations, origins, and associated health risks of specific elements in urban areas of the North China Plain. …”
Get full text

Multi-omic spatial effects on high-resolution AI-derived retinal thickness by V. E. Jackson, Y. Wu, R. Bonelli, J. P. Owen, L. W. Scott, S. Farashi, Y. Kihara, M. L. Gantner, C. Egan, K. M. Williams, B. R. E. Ansell, A. Tufail, A. Y. Lee, M. Bahlo

“…We processed the UK Biobank OCT images using a convolutional neural network to produce fine-scale retinal thickness measurements across > 29,000 points in the macula, the part of the retina responsible for human central vision. The macula is disproportionately affected by high disease burden retinal disorders such as age-related macular degeneration and diabetic retinopathy, which both involve metabolic dysregulation. …”
Get full text

Assessment tool addresses implementation challenges of ecosystem-based management principles in marine spatial planning processes by Ibon Galparsoro, Natalia Montero, Gotzon Mandiola, Iratxe Menchaca, Ángel Borja, Wesley Flannery, Stelios Katsanevakis, Simonetta Fraschetti, Erika Fabbrizzi, Michael Elliott, Maria Bas, Steve Barnard, GerJan Piet, Sylvaine Giakoumi, Maren Kruse, Ben McAteer, Robert Mzungu Runya, Olga Lukyanova, Telmo Morato, Annaïk Van Gerven, Steven Degraer, Stefan Neuenfeldt, Vanessa Stelzenmüller

“…Abstract Ecosystem-based marine spatial planning is an approach to managing maritime activities while ensuring human well-being and biodiversity conservation as key pillars for sustainable development. …”
Get full text

Daratumumab for Bortezomib-Refractory Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits in Kidney Allograft: A Case Report by Zewei Chen, Shangxi Fu, Jun Wu, Xiaoling Luo, Zhiguo Mao, Dechao Xu, Xiang Gao

“…The standard management of PGNMID has been unclear, currently based on data from small cohorts, which requires a need for additional therapeutic regimens in this disease. A human IgG monoclonal antibody that targets CD38 (daratumumab) was recently identified as a potential therapeutic option for treating PGNMID. …”
Get full text

Comparative assessment of antibacterial effect of two types of laser and their effect on morphology and mineral content of dentin by Soha Adel Abdou, Haythem S Moharrum, Elsayed Abdallah Eltayeb

“…Materials and methods The specimens used in our study were fifty four extracted human single-rooted teeth. They were collected from the Dental Department of the Research Institute of Ophthalmology, Egypt. …”
Get full text

<i>In vitro</i> assay of biological activity of a national preparation of macrophage activating factor (GcMAF-RF) by E. V. Levites, S. S. Kirikovich, E. V. Dolgova, A. S. Proskurina, G. S. Ritter, А. A. Ostanin, E. R. Chernykh, S. S. Bogachev

“…According to an original protocol, DBPs were obtained from human blood plasma using affinity chromatography, purified and modified to GcMAF-RF using cytoimmobilized glycosidases (beta-galactosidase and neuraminidase). …”
Get full text

Anatomical Adaptations of Halophyte Leaves (<i>Nitraria retusa</i> [Forsskal] Asch. and <i>Atriplex halimus</i> L.) in Response to Cement Dust Pollution in Arid Environments by Nouha Krir, Mounira Mkaddem Guedri, Mehrez Romdhane, Manel Abdullah Alshaqha

“…., in response to pollutants from a cement factory and human activities. In industrial areas, these plants absorb pollutants through their leaf surfaces, including Cu, Zn, and Pb. …”
Get full text

Does the Frequency of Watching Television Matters on Overweight and Obesity among Reproductive Age Women in Ethiopia? by Mohammed Ahmed, Abdu Seid, Adnan Kemal

Get full text

MHD effect on peristaltic motion of Williamson fluid via porous channel with suction and injection by K. Chakradhar, K. Nandagopal, Vishnudasu Prashanthi, A. Parandhama, T. Somaiah, B.V. Sai Thrinath, Nainaru Tarakaramu, Ghulam Rasool, Dilsora Abduvalieva

“…These materials play a critical role in diagnosing underlying issues within human organs that rely on peristaltic pumping for fluid transfer, such as the stomach, intestines, and ureters. …”
Get full text

Osteogenesis from Dental Pulp Derived Stem Cells: A Novel Conditioned Medium Including Melatonin within a Mixture of Hyaluronic, Butyric, and Retinoic Acids by Margherita Maioli, Valentina Basoli, Sara Santaniello, Sara Cruciani, Alessandro Palmerio Delitala, Roberto Pinna, Egle Milia, Regina Grillari-Voglauer, Vania Fontani, Salvatore Rinaldi, Roberta Muggironi, Gianfranco Pigliaru, Carlo Ventura

“…Human dental pulp stem cells (hDPSCs) have shown relevant potential for cell therapy in the orthopedic and odontoiatric fields. …”
Get full text

Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…(H. dulcis, Zhi Ju Zi) against ethanol-induced liver damage in vitro, using a human hepatoma cell line G2 (HepG2) cell model. Methods: HepG2 cells were cultured in medium containing 4% ethanol to establish a model of alcoholic liver damage. …”
Get full text

Contribution of the Geodiversity knowledge to social, economic, and environmental health development by Cassio Silva, Edson Farias Mello, Gilberto Dias Calaes, Patricia Duringer Jacques, André Luiz Invernizzi

“…These include mining, where knowledge and proper utilization of essential mineral resources are crucial for human survival and quality of life; energy, which relies on petroleum, gas, coal, peat, and other minerals for nuclear energy generation, as well as for renewable energy sources like wind and solar power. …”
Get full text

Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin by Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Hae Chan Jeong, Hyojin Kim, Mijin Kim, Seung Hae Ahn, Nataliia Lukianenko, Min Gu Jo, Hyeon Seok Bak, Sungsu Lim, Yun Kyung Kim, Ho Min Kim, Sung Bae Lee, Hyunju Cho

“…Using yeast toxicity-based screening with a random mutant library, we identify two yeast PEX19 variants and engineer equivalent mutations into human PEX19 (hsPEX19). These variants effectively delay mHttex1 aggregation in vitro and in cellular HD models. …”
Get full text

PPARα Activation Protects against Anti-Thy1 Nephritis by Suppressing Glomerular NF-κB Signaling by Koji Hashimoto, Yuji Kamijo, Takero Nakajima, Makoto Harada, Makoto Higuchi, Takashi Ehara, Hidekazu Shigematsu, Toshifumi Aoyama

“…To investigate whether PPARα activation improves the disease activity of MsPGN, we examined the protective effects of a PPARα agonist, clofibrate, in a well-established model of human MsPGN, anti-Thy1 nephritis, for the first time. …”
Get full text

Genetic coupling of enhancer activity and connectivity in gene expression control by Helen Ray-Jones, Chak Kei Sung, Lai Ting Chan, Alexander Haglund, Pavel Artemov, Monica Della Rosa, Luminita Ruje, Frances Burden, Roman Kreuzhuber, Anna Litovskikh, Eline Weyenbergh, Zoï Brusselaers, Vanessa Xue Hui Tan, Mattia Frontini, Chris Wallace, Valeriya Malysheva, Leonardo Bottolo, Elena Vigorito, Mikhail Spivakov

“…Jointly, our findings suggest an inherent genetic coupling of enhancer activity and connectivity in gene expression control relevant to human disease and highlight the regulatory role of genetically determined chromatin boundaries.…”
Get full text

Assessment of Healthcare Solid Waste Composition, Generation and its Management: the case of Two Hospitals of Shashemene Town, Oromia Regional State, Ethiopia by Gudeta Elie, Daniel Fitamo, Semere Gebreaegawi

“…If the poor healthcare solid waste management is not properly addressed at the study hospitals, human (healthcare workers, waste handlers, patients, and nearby community) and environmental health risk will be within the bounds of possibility. …”
Get full text

Structural studies of the IFNλ4 receptor complex using cryoEM enabled by protein engineering by William S. Grubbe, Bixia Zhang, Aileen Kauffman, Fabian Byléhn, Kasia Padoł, Hae-Gwang Jung, Seung Bum Park, Jessica M. Priest, Engin Özkan, Juan J. de Pablo, T. Jake Liang, Minglei Zhao, Juan L. Mendoza

“…Abstract IFNλ4 has posed a conundrum in human immunology since its discovery in 2013, with its expression linked to complications with viral clearance. …”
Get full text

The potential of the amaranth collection maintained at VIR in the context of global plant breeding and utilization trends by D. V. Sokolova, A. E. Solovieva, A. M. Zaretsky, T. V. Shelenga

“…The gene pool of amaranth preserved at VIR can provide unlimited opportunities for breeding and meet the needs of the country’s population, enriching the human diet with ingredients produced from such a health-friendly and useful crop.…”
Get full text

TNF Superfamily: A Growing Saga of Kidney Injury Modulators by Maria D. Sanchez-Niño, Alberto Benito-Martin, Sara Gonçalves, Ana B. Sanz, Alvaro C. Ucero, Maria C. Izquierdo, Adrian M. Ramos, Sergio Berzal, Rafael Selgas, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz

“…TNF-related apoptosis-inducing ligand (TRAIL and its potential decoy receptor osteoprotegerin are the two most upregulated death-related genes in human diabetic nephropathy. TRAIL activates NF-kappaB in tubular cells and promotes apoptosis in tubular cells and podocytes, especially in a high-glucose environment. …”
Get full text