Long-Term Followup of Adolescent and Young Adult Females with Hypergonadotropic Hypogonadism by Tsimaris Pantelis, Vrachnis Nikolaos, Iliodromiti Zoe, Deligeoroglou Efthymios

“…This paper presents long-term therapeutic management strategies concerning emotional health, hormone replacement therapy, maintenance of bone health, family planning, other associated disorders as well as possible research options for the future.…”
Get full text

Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis by Agnieszka Starzyk, Piotr Charzewski

“…Results: Selenium supplementation reduced TSH levels in patients without thyroid hormone replacement therapy (THRT) and significantly decreased TPOAb and MDA levels, with no impact on fT4, T3, or TGAb. …”
Get full text

Delirious Mania Associated with Autoimmune Gastrothyroidal Syndrome of a Mid-Life Female: The Role of Hashimoto Encephalopathy and a 3-Year Follow-Up including Serum Autoantibody L... by Udo Bonnet, Claudia Selle, Ralf Kuhlmann

“…A potential contribution of bipolar disorder and metabolic encephalopathies due to severe hypothyroidism, glucocorticoid treatment, accelerated thyroid hormone replacement therapy, or vitamin B deficiency is critically discussed. …”
Get full text

Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm by Soheila Aminimoghaddam, Narmin Karisani, Maryam Mazloomi, Maryam Rahimi

“…She was managed with thyroid hormone replacement therapy and her condition improved after 6 weeks. …”
Get full text

Gonadal Hormone Changes with Aging and Their Impact on Chronic Pain by Onella Athnaiel, Nicholas Davidson, Jaskaran Mangat, Ned F. Nasr, Nebojsa Nick Knezevic

“…Women tend to experience less pain with aging compared to their premenopausal years, and this is partially explained by the fact that estrogen enhances pain sensitivity and its decline during menopause decreases it. However, hormone replacement therapy (HRT) seems to increase pain tolerance post-menopause. …”
Get full text

Bidirectional Interaction of Thyroid-Kidney Organs in Disease States by Fateme Shamekhi Amiri

“…Reduced mean values of thyroid function profiles after treatment suggest that this thyroid disease should be considered and ameliorated with thyroid hormone replacement therapy in patients with kidney disease.…”
Get full text

Histological changes of endocervical polypoid lesions in women at reproductive age by Muna Zuhair Al-Hamdany, Mustafa Salah Fadhil

“…Materials and Methods: Sixty specimens of the resected cervical polyps were obtained from Al-Salaam Teaching Hospital in Mosul city during the period from June 2021 to February 2022, women diagnosed to have cervical polyps on per speculum examination were given a time to be operated on with exclusion of pregnant, postmenopausal women, those on hormone replacement therapy, and those below 20 years. After polypectomy, fixation of biopsies in 10% buffered formalin was done followed by processing and staining with hematoxylin and eosin for histological examination. …”
Get full text

Delayed Recovery after Nonoperative Treatment of an Avulsion Fracture of the Ischial Tuberosity in an Adolescent Gymnast with a History of Growth Hormone Deficiency: A Case Report by Prashant Meshram, Amar S. Vadhera, Rahul Sachdev, Edward G. McFarland

“…She had been diagnosed with isolated growth hormone deficiency at age 4 and was treated with growth hormone replacement therapy until age 14. Six months before presentation, she experienced the insidious onset of dull, aching pain in her right hamstring, near the junction of the thigh and buttocks, that was believed to be the result of a chronic hamstring strain. …”
Get full text

Risk Factors for Breast Cancer in the Female Population by Yoenny Peña García, Maikel Maceo González, Diamela Ávila Céspedes, Licet Utria Velázquez, Yohandra Más López

“…<br /><strong>Results:</strong> the greatest association strength risk factors were: births in advance age, smoking, hormone replacement therapy and late menopause. <br /><strong>Conclusions:</strong> it was demonstrated that risk factors for breast cancer which affect the territory in order of importance are: family history of breast cancer, late menopause, hormonal treatment, nulliparity, smoking, deliveries in advanced age, early menarche, alcoholism, obesity, non-breastfeeding, and inadequate diet.…”
Get full text

The Association between Female Reproductive Factors and Open-Angle Glaucoma in Korean Women: The Korean National Health and Nutrition Examination Survey V by Yong Un Shin, Eun Hee Hong, Min Ho Kang, Heeyoon Cho, Mincheol Seong

“…Associations between undiagnosed OAG and female reproductive factors such as age at menarche and menopause, parity, history of lactation, and administration of oral contraceptives (OC) or hormone replacement therapy (HRT) were determined using stepwise logistic regression analyses. …”
Get full text

Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing by Carolina L. Bellera, Darío E. Balcazar, Lucas Alberca, Carlos A. Labriola, Alan Talevi, Carolina Carrillo

“…Among them, levothyroxine, traditionally used in hormone replacement therapy in patients with hypothyroidism, showed dose-dependent inhibition of Cz and antiproliferative activity on the parasite.…”
Get full text

Effect of autologous platelet-rich plasma treatment on patients with thin endometrium by Tung Nguyen Thanh, Ai Hoang Van, Son Trinh The, Lan Do Ngoc, Hang Doan Thi, Trang Quan Van, Khoa Ba Tran, Sang Trieu Tien

“…Methods: In 34 patients with thin endometrium (< 7 mm), canceled in the previous frozen embryo transfer cycles, autologous platelet-rich plasma was prepared, from autologous peripheral vein blood; intrauterine infusion was given during hormone replacement therapy in frozen embryo transfer cycles. …”
Get full text

Application and progress of 3D printed biomaterials in osteoporosis by Chenxu Wang, Chenxu Wang, Aiguo Liu, Aiguo Liu, Ziwen Zhao, Ting Ying, Shuang Deng, Zhen Jian, Xu Zhang, Chengqing Yi, Dejian Li

“…Conventional treatments, such as pharmaceutical drugs and hormone replacement therapy, often yield suboptimal results and are frequently associated with side effects. …”
Get full text

QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite by Namrata Gautam, Debopriya Dutta, Saurabh Mittal, Perwez Alam, Nasr A. Emad, Mohamed H. Al-Sabri, Suraj Pal Verma, Sushama Talegaonkar

“…Abstract The repercussions of hormone replacement therapy (HRT) and bisphosphonates pose serious clinical challenges and warrant novel therapies for osteoporosis in menopausal women. …”
Get full text

Impact of the COVID-19 pandemic on cerebral venous sinus thrombosis in China: a comparative study by Xiaoming Zhang, Kun Fang, Duo Lan, Xiangqian Huang, Xunming Ji, Ran Meng, Da Zhou

“…Poor outcomes were associated with central nervous system (CNS) infection, oral contraceptive use or hormone replacement therapy (HRT), hematologic disorders, anemia, and prothrombotic conditions. …”
Get full text

A Network Investigation on Idiopathic Hypogonadotropic Hypogonadism in China by Weiwei Zhao, Hongying Ye, Xiaolong Zhao, Zhaoyun Zhang, Shouyue Sun, Yiran Jiang, Min He, Cheng Xu, Renming Hu, Yiming Li

“…The results of our cross-sectional study showed the effectiveness of hormone replacement therapy for IHH and implied that gonadotropin and androgen replacement therapy may be superior to gonadotropin treatment alone.…”
Get full text

Factors associated with low bone mineral density in Turner syndrome: a multicenter prospective observational study by Kento Ikegawa, Eri Koga, Tomoyo Itonaga, Hideya Sakakibara, Masanobu Kawai, Yukihiro Hasegawa

“…In total, 48 patients with TS aged between 5 and 49 years comprising a pre-pubertal group (n = 9), a cyclical menstruation group (n = 6), and a hormone replacement therapy (HRT) group (n = 33) were enrolled. …”
Get full text

The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s Thyroiditis by Stana Tokić, Mario Štefanić, Ljubica Glavaš-Obrovac, Sonja Jaman, Eva Novosadová, Jana Petrkova, Zdenka Navratilova, Mirjana Suver Stević, Martin Petrek

“…To shed more light on CD4+ subsets role in HT, we investigated the mRNA expression levels of several Th1/Treg-associated transcription factors (T-bet/ETS1, HIF1α/BLIMP1/FOXP3) in peripheral blood T cells of 10 hypothyroid, untreated HT patients, 10 hypothyroid patients undergoing hormone replacement therapy, 12 euthyroid HT subjects, and 11 healthy controls by the qRT-PCR. …”
Get full text

Factors influencing endometrial receptivity in women with recurrent implantation failure by Katarzyna Opuchlik, Katarzyna Pankiewicz, Piotr Pierzyński, Janusz Sierdziński, Elina Aleksejeva, Andres Salumets, Tadeusz Issat, Piotr Laudański

“…After preparation of the endometrium by the hormone replacement therapy endometrial biopsies were taken from each patient and sequenced with beREADY test TAC targeting 67 biomarker genes for endometrial receptivity. …”
Get full text

Endocrine Adverse Events in Patients Treated with Immune Checkpoint Inhibitors: A Comprehensive Analysis by Meriç Dökmetaş, Harun Muğlu, Erkan Özcan, Buket Bayram Kuvvet, Kaan Helvacı, Ender Kalacı, Seda Kahraman, Musa Barış Aykan, İrfan Çiçin, Fatih Selçukbiricik, Ömer Fatih Ölmez, Ahmet Bilici

“…Most cases were managed conservatively or with hormone replacement therapy. Patients who developed endocrine irAEs exhibited a higher objective response rate (ORR) and clinical benefit rate (CBR) compared to those without irAEs. …”
Get full text