Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato by Jianling Zhang, Xiaoying Liu, Zuozhen Yin, Tiantian Zhao, Dan Du, Jing Li, Mingku Zhu, Yueying Sun, Yu Pan

“…The expression profiles of selected <i>SlbHLHs</i> were varyingly and markedly induced by multiple abiotic stresses and hormone treatments. These results provide valuable information to further understand the significance and intricacy of the bHLH transcription factor family, and lay a foundation for further exploring functions and possible regulatory mechanisms of SlbHLH members in abiotic stress tolerance, which will be significant for the study of tomato stress resistance and agricultural productivity.…”
Get full text

Does Baseline Serum Androgen Levels Have an Impact on Ovulation Induction Cycle Outcomes by Using Clomifene Citrate among Infertile Women with Polycystic Ovary Syndrome? A Retrospe... by Serkan Kahyaoglu, Muzeyyen Gulnur Ozaksit, Gozde Karacan Duman, Deniz Ozturk Atan, Inci Kahyaoğlu, Meryem Kuru Pekcan, Ozlem Moraloglu Tekin

“…RESULTS: Serum basal follicular stimulating hormone, LH, E2, fasting cholesterol, glucose, and HOMA-IR levels were comparable between these two groups of patients. …”
Get full text

Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates depression-like behaviour in female mice after a mild chronic stress paradigm by Christa Hohoff, Nicole Kerkenberg, Mingyue Zhang, Weronika Palkowska, Lydia Wachsmuth, Maja Peng, Lena Stiehl, Christiane Schettler, Johannes C. S. Zang, Andreas Huge, Evgeni Ponimaskin, Cornelius Faber, Bernhard T. Baune, Weiqi Zhang

“…These effects are partly mediated by sex and sex steroid hormones, which in turn are affected by the palmitoyl acyltransferase ZDHHC7. …”
Get full text

Dose-Escalated Hypofractionated Intensity-Modulated Radiotherapy in High-Risk Carcinoma of the Prostate: Outcome and Late Toxicity by David Thomson, Sophie Merrick, Ric Swindell, Joanna Coote, Kay Kelly, Julie Stratford, James Wylie, Richard Cowan, Tony Elliott, John Logue, Ananya Choudhury, Jacqueline Livsey

“…All patients received neoadjuvant hormone therapy, completing up to 6 months in total. …”
Get full text

Major royal-jelly proteins intake modulates immune functions and gut microbiota in mice by Hang Wu, Shican Zhou, Wenjuan Ning, Xiao Wu, Xiaoxiao Xu, Zejin Liu, Wenhua Liu, Kun Liu, Lirong Shen, Junpeng Wang

“…Our results showed that MRJPs are important components of royal jelly that modulate host immunity and hormone levels and help maintain gut microbiota stability.…”
Get full text

Thyroid Dysfunction in Patients with Metabolic Syndrome: A Cross-Sectional, Epidemiological, Pan-India Study by Vaishali Deshmukh, Faraz Farishta, Milind Bhole

“…Overt hypothyroidism was defined as thyroid-stimulating hormone TSH>4.50 μIU/mL with free thyroxine FT4<0.8 ng/dL and free triiodothyronine FT3<1.4 pg/mL; subclinical hypothyroidism as TSH>4.50 μIU/mL with FT4=0.8-1.8 ng/dL and FT3=1.4-4.4 pg/mL; overt hyperthyroidism as TSH<0.45 μIU/mL with FT4>1.8 ng/dL and FT3>4.4 pg/mL; and subclinical hyperthyroidism as TSH<0.45 μIU/mL with FT4=0.8-1.8 ng/dL and FT3=1.4-4.4 pg/mL. …”
Get full text

Muramyl Dipeptide Enhances Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption through Increased RANKL Expression in Stromal Cells by Masahiko Ishida, Hideki Kitaura, Keisuke Kimura, Haruki Sugisawa, Tomo Aonuma, Haruhiko Takada, Teruko Takano-Yamamoto

“…On the other hand, MDP had no effect on osteoclastogenesis in parathyroid hormone administrated mice. MDP enhanced LPS-induced receptor activator of NF-κB ligand (RANKL) expression and Toll-like receptor 4 (TLR4) expression in vivo and in stromal cells in vitro. …”
Get full text

Analysis of factors affecting pregnancy outcomes in patients with adenomyosis after high intensity focused ultrasound ablation: a retrospective study by Rong Ma, Diego Armando Burgos Briones, Min Zou, Yu Xiong, Jin Bai, Lian Zhang

“…Factors influencing pregnancy outcomes were analyzed using multivariate regression analysis and survival analysis.Results After HIFU, 100 of 231 (43.3%) patients became pregnant within 96 months, including 77 (77/194, 39.7%) in natural and 23 (23/37, 62.2%) in vitro fertilization and embryo transfer (IVF-ET) pregnancies following gonadotropin-releasing hormone agonist (GnRHa). Among the 108 (46.8%, 108/231) infertile patients (defined as the failure to achieve pregnancy after 12 months of regular unprotected sexual intercourse, 40 primary infertility and 68 secondary infertility), 31 (28.7%) became pregnant. …”
Get full text

Regulation of energy balance by leptin as an adiposity signal and modulator of the reward system by Roshanak Asgari, Maria Caceres-Valdiviezo, Sally Wu, Laurie Hamel, Bailey E. Humber, Sri Mahavir Agarwal, Paul J. Fletcher, Stephanie Fulton, Margaret K. Hahn, Sandra Pereira

“…Background: Leptin is an adipose tissue-derived hormone that plays a crucial role in body weight, appetite, and behaviour regulation. …”
Get full text

Non-parathyroid hypercalcemia in a patient with new-onset hyperthyroidism and silicone-induced granulomas: case report by Laura Montefusco, Giada Rossi, Iulia Petria, Ida Pastore, Ida Pastore, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina

“…Suppressed parathyroid hormone (PTH) levels excluded PTH-mediated hypercalcemia (e.g., primary hyperparathyroidism) and among causes of non-PTH-mediated hypercalcemia, malignancies were excluded. …”
Get full text

Aggravating Effects of Psychological Stress on Ligature-Induced Periodontitis via the Involvement of Local Oxidative Damage and NF-κB Activation by Qiang Li, Yajuan Zhao, Daokun Deng, Jiuhui Yang, Yongjin Chen, Jia Liu, Min Zhang

“…Four weeks later, stressed rats showed altered behaviour, serum hormone levels, and sucrose preference. More obvious alveolar bone loss and attachment loss and higher protein expressions of inflammatory cytokines were observed in the experimental periodontitis plus psychological stress group. …”
Get full text

Thyroid function abnormalities in individuals with sickle cell disease: a meta-analysis by Sagad O. O. Mohamed, Hussein Ahmed, Mohammed A. H. Mohammednoor, Khalefa B. K. Alzubeir, Safaa Fadlelmoula, Osman O. A. Abdallah, Izzut Awad Ahmed

“…Serum thyroid-stimulating hormone (TSH) levels were significantly higher in SCD patients compared to controls (SMD = 1.184; 95% CI, 0.269–2.099; p = 0.011). …”
Get full text

Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells by Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri

“…Dysfunctions of the hypothalamus-pituitary-growth hormone/insulin growth factor-I axis, hypothalamus-pituitary-thyroid axis, and hypothalamus-pituitary-adrenal axis were documented as later complicances, occurring in about 10, 30, and 40–50% of transplanted patients, respectively. …”
Get full text

Diagnostic uncertainty in primary aldosteronism by Marković Bojan, Stojković Mirjana, Janić Tamara, Babić Jovana, Đurković Ivana, Joksimović Nata, Nedeljković-Beleslin Biljana, Ćirić Jasmina, Žarković Miloš

“…Aldosterone is a mineralocorticoid hormone originating from the glomerulosa zone of the adrenal cortex. …”
Get full text

Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF by Yang Liu, Yiran Zhao, Chengliang Zhou, Hong Zhu, Jiexue Pan, Jing Fu, Hefeng Huang, Hui Lin, Li Jin

“…Serum was collected before ovulation induction, follicular fluid (FF) and aspirates were obtained during oocyte retrieval for flow cytometry, cytokines, hormone, and lipid profiles measurement. Clinical outcomes were recorded through a one-year follow-up. …”
Get full text

High-dose glucocorticoid treatment vs. glucocorticoid replacement in immune checkpoint inhibitor associated hypophysitis (CORTICI): an open, randomised controlled trial by Verena Theiler-Schwetz, Christian Trummer, Lisa Schmitt, Angelika Terbuch, Barbara Obermayer-Pietsch, Erika Richtig, Stefan Pilz

“…The primary outcome was the frequency of hormonal axes recovery.Results Between 17th April 2019 and 16th September 2022, 18 out of the 20 randomised patients finished the trial; eight completed high-dose, 10 glucocorticoid replacement. …”
Get full text

Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins by A. Catania, G. Colombo, C. Rossi, A. Carlin, A. Sordi, C. Lonati, F. Turcatti, P. Leonardi, P. Grieco, S. Gatti

“…Several properties of α-melanocyte stimulating hormone (α-MSH) suggested that it could be a natural antimicrobial peptide. α-MSH is a primordial peptide that appeared during the Paleozoic era, long before adaptive immunity developed and, like natural antimicrobial molecules, is produced by barrier epithelia, immunocytes, and within the central nervous system. α-MSH was discovered to have antimicrobial activity against two representative pathogens, Staphylococcus aureus and Candida albicans. …”
Get full text

Association of vaginal oestradiol and the rate of breast cancer in Denmark: registry based, case-control study, nested in a nationwide cohort by Christian Torp-Pedersen, Lina Steinrud Mørch, Nelsan Pourhadi, Amani Meaidi, Ellen Christine Løkkegaard

“…Exclusions were a history of cancer, mastectomy, use of systemic hormone treatment, use of the levonorgestrel releasing intrauterine system, or use of vaginal oestrogen treatments other than oestradiol tablets. …”
Get full text

Effect of partial oocyte maturation before ovum pick up on developmental competence of buffalo oocytes by Amjad Riaz, Muhammad K. Ashraf, Talha Ashraf, Ali Husnain, Muhammad Yaseen, Muhammad H. Mushtaq, Burhan E. Azam

“…Starting on Day 2 of the experiment, the ovaries of buffalo were super- stimulated with six equally divided doses of 33.3 mg per dose of porcine follicle stimulating hormone (Vetoquinol, Magny-Vernois, France) i.m., for three days with 12 h interval. …”
Get full text

B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer by Nicole J. Toney, Lynn M. Opdenaker, Lisa Frerichs, Shirin R. Modarai, Aihui Ma, Holly Archinal, Grace O. Ajayi, Jennifer Sims-Mourtada

“…This highlights the potential of IL-1 inhibitors as preventive and therapeutic options for hormone receptor-negative DCIS and TNBC.…”
Get full text