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1641
Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom
Published 2019-04-01“…**Objective:** To evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with hormone receptor positive (HR+) and human epidermal growth receptor 2 negative (HER2-) advanced breast cancer from a UK payer perspective. …”
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1642
Impact of Seasonal Variations on Semen Parameters: A Retrospective Analysis of Data from Subjects Attending a Tertiary Care Fertility Centre
Published 2023-04-01“…The data of azoospermic and severe oligospermic (<5 million/mL) men and those receiving hormone treatment were excluded. Statistical Analysis Used: Data were analysed using SPSS 23 and variables expressed as mean and standard deviation. …”
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1643
Revisiting microgenderome: detecting and cataloguing sexually unique and enriched species in human microbiomes
Published 2024-12-01“…Abstract Background Microgenderome or arguably more accurately microsexome refers to studies on sexual dimorphism of human microbiomes aimed at investigating bidirectional interactions between human microbiomes, sex hormones, and immune systems. It is important because of its implications to disease susceptibility and therapy, in which men and women demonstrate divergence in many diseases especially autoimmune diseases. …”
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1644
Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet
Published 2018-01-01“…This study approached several questions: (1) does a western-style diet (WSD) contribute to sedentary behavior or is sedentary behavior a consequence of obesity and (2) does estradiol (E) hormone therapy offset WSD or ameliorate sedentary behavior? …”
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1645
Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis
Published 2025-01-01“…Predicted target genes of these miRNAs are involved in calcium channel signaling, osmotic regulation, plant hormone signaling, and reactive oxygen species clearance. …”
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1646
Thermogenic Effect of Glucose in Hypothyroid Subjects
Published 2014-01-01“…The importance of thyroid hormone, catecholamines, and insulin in modification of the thermogenic effect of glucose (TEG) was examined in 34 healthy and 32 hypothyroid subjects. …”
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1647
Changes in Locomotor Activity Observed During Acute Nicotine Withdrawal Can Be Attenuated by Ghrelin and GHRP-6 in Rats
Published 2025-01-01“…<b>Background/Objectives:</b> Ghrelin and growth hormone-releasing peptide 6 (GHRP-6) are peptides which can stimulate GH release, acting through the same receptor. …”
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1648
Sarco(endo)plasmic Reticulum Ca2+-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene
Published 2002-01-01“…It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE). There are two other conserved regulatory regions located between positions -410 to -661 bp and from -919 to -1410 bp. …”
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1649
Non-trivial uses of melatonin: Its effects on sleep, jet lag, obesity, migraine, and gastrointestinal disorders
Published 2025-02-01“…In this literature review, the authors intended to introduce the latest scientific evidence on the influence of the sleep hormone not only on the quality of time spent in bed and jet lag, but also to consider possible other positive impacts. …”
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1650
Interspecific Variations in Interplant Communication and Ecological Characteristics in Trees
Published 2025-01-01“…These results are partially supported by plant hormone analysis. In addition, the presence of inter‐plant communication was positively correlated with both the number of leaves per shoot (complexity of plant architecture) and population density. …”
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1651
Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context
Published 2013-01-01“…HCA have been observed in many pathological conditions such as glycogenosis, familial adenomatous polyposis, MODY3, after male hormone administration, and in vascular diseases. …”
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1652
Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin.
Published 2025-01-01“…We identified a quantitative trait locus (QTL) on chromosome V independent of all beta-tubulin genes and overlapping with two promising candidate genes, the cytochrome P450 gene cyp-35D1 and the nuclear hormone receptor nhr-176. Both genes were previously demonstrated to play a role in TBZ metabolism. …”
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1653
Association of Serum Melatonin Level with Mild Cognitive Impairment in Type 2 Diabetic Patients: A Cross-Sectional Study
Published 2021-01-01“…Melatonin is an essential neuroendocrine hormone that participates in the regulation of sleep rhythm and cognitive function. …”
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1654
Long-Term Follow-Up of Patients with 46,XY Partial Gonadal Dysgenesis Reared as Males
Published 2014-01-01“…Studies on 46,XY partial gonadal dysgenesis (PGD) have focused on molecular, gonadal, genital, and hormone features; little is known about follow-up. …”
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1655
Assessment of Myometrial Concentrations of Oestrogen and Progesterone Receptors in the Lower Uterine Segment of Full-Term Pregnancies in Presence or Absence of Labour
Published 2013-01-01“…The biopsy of myometrium was realized during caesarian section, and the excised tissue was stained using immunohistochemical techniques for the quantification of the receptors, and with the aid of image-analysis software, the numbers of receptors for each hormone were determined spectrophotometrically. The Mann-Whitney test was used to compare the pregnant women in each study group with respect to the numbers of ORs and PRs. …”
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1656
Flavouring group evaluation 420 (FGE.420): Hesperetin dihydrochalcone
Published 2024-12-01“…In a 90‐day toxicity study, indications were obtained that the substance affects thyroid hormone levels at all doses tested (100–1000 mg/kg bw per day). …”
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1657
Physiological and molecular mechanisms of exogenous salicylic acid in enhancing salt tolerance in tobacco seedlings by regulating antioxidant defence system and gene expression
Published 2025-01-01“…IntroductionSalt stress has emerged as a predominant abiotic factor that jeopardizes global crop growth and yield. The plant hormone salicylic acid (SA) has notable potential in mitigating salt toxicity, yet its mechanism in enhancing the salinity tolerance of tobacco plants is not well explored.MethodsThis study aimed to assess the potential benefits of exogenous SA application (1.0 mM) on tobacco seedlings subjected to saline soil conditions.ResultsThe foliar spray of SA partially mitigated these salt-induced effects, as evidenced by a reduction of malondialdehyde content, and improvements of leaf K+/Na+ ratios, pigment biosynthesis, and electron transport efficiency under NaCl stress. …”
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1658
Gender Differences in the Neurobiology of Anxiety: Focus on Adult Hippocampal Neurogenesis
Published 2016-01-01“…The differences between male and female physiologies are greatly influenced by hormonal differences. Gonadal hormones and their fluctuations during the estrous cycle have often been identified as agents responsible for sexual dimorphism in behavior and AHN. …”
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1659
Detection and Analysis of Autoantigens Targeted by Autoantibodies in Immunorelated Pancytopenia
Published 2013-01-01“…Most patients responded well to adrenocortical hormone and/or high-dose intravenous immunoglobulin treatment, indicating that cytopenia might be mediated by autoantibodies. …”
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1660
A Mechanism Exploration of Metabolic Syndrome Causing Nodular Thyroid Disease
Published 2019-01-01“…After matching age, gender, uric acid (UA), and creatinine (Cr) by propensity score matching (PSM), subjects with MS had higher prevalence of TNs than those without MS, as well as higher thyroid-stimulating hormone (TSH) and inflammatory levels, indicated by the higher white blood cell (WBC), lymphocyte (LY), and monocyte/high-density lipoprotein (Mo/HDL). …”
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