Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

“…Methods: Adult patients at least 18 years old diagnosed with hormone receptor positive, HER2− receptor negative MBC with a performance status of 0 or 1 who have been treated with capecitabine in the metastatic setting and up to two other lines of chemotherapy, including a taxane, were enrolled in this single-arm, multicentre, phase 2 study in the Netherlands. …”
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Impact of comb type on production performance, egg production quality, reproductive performance, and blood biochemical indexes in Tianfu chickens by Yuxin Zhou, Hengyong Xu, Wei Du, Yuxiang Lu, Zhi Hu, Qingqing Deng, Xi Wang, Yiping Liu, Yao Zhang, Yan Wang

“…Blood analysis revealed higher calcitonin and parathyroid hormone levels in single-comb hens, while rose-comb hens had higher blood calcium and phosphorus levels. …”
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60-month follow-up of Long Limb vs. Standard Limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT by Saleem Ansari, Anna Kamocka, Tina Mazaheri, Ibiyemi Ilesanmi, Lara Jimenez-Pacheco, Kleopatra Alexiadou, Joanna Tan, Harvinder Chahal, Krishna Moorthy, Sanjay Purkayastha, Anne Margot Umpleby, Stephen Robert Bloom, Francesco Rubino, Alexander Dimitri Miras, Ahmed Rashid Ahmed, Tricia Tan

“…Mixed-meal tolerance tests and a hyperinsulinaemic-euglycaemic clamp were used to measure postprandial gut hormone response, glucose tolerance and insulin sensitivity. …”
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Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications by Jiayi He, Huiqian Zhang, Hehua Quan, Qingyuan Wang, Congcong Wen, Yiyan Wang, Yang Zhu, Ren-Shan Ge, Xiaoheng Li

“…The findings indicated that BPB significantly reduced the serum testosterone levels at the dose of 100 mg/kg and 200 mg/kg and follicle-stimulating hormone levels at the doses of 50, 100, and 200 mg/kg, while increasing estradiol levels at the dose of 200 mg/kg. …”
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Connecting The Dots: The Impact Of Subclinical Hypothyroidism On Female Subfertility And Obesity by Naila Ashfaq, Warda Hussain, Mugheera Hussain, Neelam Saba, Asma Muddasir, Jawairiah Liaqat

“…Females were enquired about infertility status and their thyroid status was measured in terms of thyroid stimulating hormone (TSH) and free thyroxine (FT4). Mean and Standard Deviation were used for quantitative variables whereas frequency and percentages were used for categorical variables. …”
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Cyclopiazonic acid suppresses the function of Leydig cells in prepubertal male rats by disrupting mitofusin 1-mediated mitochondrial function by Hang Lin, Ming Su, He Zhu, Yang Yu, Jianmin Sang, Yiyan Wang, Qiqi Zhu, Yang Zhu, Xiaoheng Li, Xingwang Li, Ren-Shan Ge, Huitao Li

“…In vivo, Sprague Dawley rats received CPA (0.2, 1, 5 mg/kg/day) via gavage from postnatal days 21–28 to evaluate PLC function and mitochondrial morphology using serum hormone levels, histology, qPCR, and Western blot analyses. …”
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Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease by Xian Shao, Suhua Gao, Pufei Bai, Qian Yang, Yao Lin, Mingzhen Pang, Weixi Wu, Lihua Wang, Ying Li, Saijun Zhou, Hongyan Liu, Pei Yu

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Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway by Minxia Zuo, Cheng Meng, Qian Song, Zhongai Gao, Xiao Cui, Jingyu Wang, Yongmei Li, Xiaochen Li, Chunyan Shan, Juhong Yang, Baocheng Chang

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Menopausal shift on women’s health and microbial niches by Maria R. Nieto, Maria J. Rus, Victoria Areal-Quecuty, Daniel M. Lubián-López, Aurea Simon-Soro

“…The microbial metabolism of sex hormones highlights the bidirectional relationship between hormones and the microbiome. …”
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Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling by Ying Cheng, Man Zhang, Chenguang Li, Long Su, Lingli Fu, Shi Wu, Chaofei Xu, Bei Sun, Liming Chen

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Cutin formation in tomato is controlled by a multipartite module of synergistic and antagonistic transcription factors by Yuan Shi, Changhao Deng, Xiangyin Lu, Yan Wang, Yaowen Pan, Deding Su, Wang Lu, Yuxiang Lin, Rui Li, Junnan Han, Yanwei Hao, Yi Chen, Ghassen Abid, Julien Pirrello, Mondher Bouzayen, Yudong Liu, Zhengguo Li, Baowen Huang

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GLP‐1 Receptor Agonists Alleviate Diabetic Kidney Injury via β‐Klotho‐Mediated Ferroptosis Inhibition by Shasha Tian, Saijun Zhou, Weixi Wu, Yao lin, Tongdan Wang, Haizhen Sun, A‐Shan‐Jiang A‐Ni‐Wan, Yaru Li, Chongyang Wang, Xiaogang Li, Pei Yu, Yanjun Zhao

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The association between metabolomic profiles of lifestyle and the latent phase of incident chronic kidney disease in the UK Population by Tingting Jin, Yunqi Wu, Siyi Zhang, Ya Peng, Yao Lin, Saijun Zhou, Hongyan Liu, Pei Yu

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Estimation of calcitonin and calcitonin gene-related peptide-α in bone calcification in quail during laying period by Hadeel M. Hameed, Soulaf J. Kakel

“…Maintaining the balance of calcium, phosphorus, and their regulating hormones is essential in laying hens to preserve the quality of the eggs and the framework. …”
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Effects of IAA, IBA, NAA, and GA3 on Rooting and Morphological Features of Melissa officinalis L. Stem Cuttings by Hakan Sevik, Kerim Guney

“…Even though the auxin group hormones (IAA, IBA, and NAA) do not have an apparent effect on rooting percentage, these hormones were detected to affect the morphological characteristics of the newly generated plants, especially root generation. …”
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Analysis of Circulating MicroRNAs In Vivo following Administration of Dexamethasone and Adrenocorticotropin by Ivan Igaz, Gábor Nyírő, Zoltán Nagy, Henriett Butz, Zsolt Nagy, Pál Perge, Peter Sahin, Miklós Tóth, Károly Rácz, Peter Igaz, Attila Patócs

“…Purpose. The interaction of hormones of the pituitary-adrenal axis and adrenal cortex-associated circulating microRNAs is mostly unknown. …”
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The BES1/BZR1 transcriptional factor SlBES2 regulates photosynthetic apparatus in tomato fruit by Ming Huang, Wenjing Liu, Deding Su, Ghassen Abid, Baowen Huang, Zhengguo Li

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Mitotane-Induced Hyperlipidemia: A Retrospective Cohort Study by Hassan Shawa, Ferhat Deniz, Hadil Bazerbashi, Mike Hernandez, Rena Vassilopoulou-Sellin, Camilo Jimenez, Mouhammed Amir Habra

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Hubungan antara Stres dengan Pola Siklus Menstruasi Mahasiswi Fakultas Kedokteran Universitas Andalas by Nurul Aini Yudita, Amel Yanis, Detty Iryani

“…Stres merangsang  hypothalamus-pituitary-adrenal  cortex  aksis  sehingga  dihasilkan hormon kortisol. Hormon kortisol menyebabkan terjadinya ketidakseimbangan hormonal termasuk hormon reproduksi sehingga mempengaruhi siklus menstruasi. …”
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Causes and Metabolic Consequences of Gynecomastia in Adult Patients by Ralitsa Robeva, Atanaska Elenkova, Sabina Zacharieva

“…Anthropometric, metabolic, and hormonal data of the patients were collected. Results. …”
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