Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans by Shakun Karki, Melissa G. Farb, Samantha Myers, Caroline Apovian, Donald T. Hess, Noyan Gokce

“…We performed adipose tissue mRNA expression of proteins involved in triglyceride hydrolysis and correlated their weight loss induced alterations with systemic parameters associated with cardiovascular disease risk. mRNA transcripts of adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and lipid droplet proteins comparative gene identification 58 (CGI-58) and perilipin increased significantly after weight loss (p<0.05 for all). …”
Get full text

Finding the Culprit: Cushing Syndrome Secondary to Lung Carcinoid Tumor by Richard Vaca, MD, Nirali A. Shah, MD

“…Background/Objective: Cushing syndrome resulting from ectopic adrenocorticotropic hormone (ACTH) secretion (EAS) is a rare condition, and its occurrence in adolescents is even more uncommon, representing <1% of cases. …”
Get full text

Features of cardiovascular magnetic resonance native T1 mapping in maintenance hemodialysis patients and their related factors by Changqin Zhang, Lijing Yao, Min Liu, Yilun Zhou

“…In the HD group, the global native T1 value correlated positively with intact parathyroid hormone (iPTH) (r = 0.418, p = 0.017) and negatively with triglycerides (r= −0.366, p = 0.039). …”
Get full text

A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…IL-1β is a strong regulator of Brain Natriuretic Peptide (BNP), a hormone involved in cardiovascular homeostasis by guanylyl cyclase Natriuretic Peptide Receptor (NPR-1). …”
Get full text

A New Hope for the Patients of Non‐Alcoholic Steatohepatitis: FDA Gives Green Signal for Resmetirom Use by Abdul Haseeb Hasan, Muhammad Ali Abid, Muhammad Hafi Abid, Laiba Suhail, Abubakar Nazir

“…Recently, resmetirom, a thyroid hormone receptor‐β agonist, received FDA approval for treating NASH, offering new hope to patients. …”
Get full text

Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer? by Tryambak Pratap Srivastava, Ruby Dhar, Subhradip Karmakar

“…In breast cancer, AR exhibits diverse functions across subtypes, often interacting with other hormone receptors, thereby influencing tumor progression and treatment responses. …”
Get full text

Impact of Resistance Exercise under Hypoxia on Postexercise Hemodynamics in Healthy Young Males by Masahiro Horiuchi, Arisa Ni-i-nou, Mitsuhiro Miyazaki, Daisuke Ando, Katsuhiro Koyama

“…The MAP at 20 and 30 min of recovery in hypoxia was significantly lower than in normoxia (P < 0.05, respectively). The antidiuretic hormone significantly increased after 60 min of recovery in both conditions; moreover, the values in hypoxia were significantly higher than those in normoxia (P < 0.05). …”
Get full text

The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Releva... by Kvido Smitka, Hana Papezova, Karel Vondra, Martin Hill, Vojtech Hainer, Jara Nedvidkova

“…The gut-brain-adipose tissue (AT) peptides and neutralizing autoantibodies play an important role in the regulation of eating behavior and growth hormone release. The mechanisms for controlling food intake involve an interplay between gut, brain, and AT. …”
Get full text

Thyroid-Disrupting Activities of Groundwater from a Riverbank Filtration System in Wuchang City, China: Seasonal Distribution and Human Health Risk Assessment by Dongdong Kong, Hedan Liu, Yun Liu, Yafei Wang, Jian Li

“…The recombinant thyroid hormone receptor (TR) gene yeast assay was used to evaluate thyroid disruption caused by groundwater from the riverbank filtration (RBF) system in Wuchang City, China. …”
Get full text

Biological Characteristics and Medical Treatment of Breast Cancer in Young Women—A Featured Population: Results from the NORA Study by P. Pronzato, G. Mustacchi, A. De Matteis, F. Di Costanzo, E. Rulli, I. Floriani, M. E. Cazzaniga

“…Positive nodal status, large tumors, and elevated Ki67 all associated with the choice for chemotherapy followed by endocrine therapy in hormone receptor-positive patients (𝑃<.0001). At univariate analysis, ER-ve status, chemotherapy and age resulted as the only statistically significant variables (HR=2.02, 𝑃=.004, and >40 versus ≤40, 𝑃<.0001, resp.). …”
Get full text

Cangfudaotan Decoction Alleviates Insulin Resistance and Improves Follicular Development in Rats with Polycystic Ovary Syndrome via IGF-1-PI3K/Akt-Bax/Bcl-2 Pathway by Chenye Wang, Caifei Ding, Zhoujia Hua, Chunyue Chen, Jia Yu

“…CFD was able to improve IR, restore the serum hormone levels, inhibit the inflammatory cytokines in PCOS rat, and alleviate ovary morphological injury and apoptosis in PCOS rats. …”
Get full text

Effects of Selenium Supplement on B Lymphocyte Activity in Experimental Autoimmune Thyroiditis Rats by Yang Li, Xinhe Zuo, Chuan Hua, Yong Zhao, Xun Pei, Man Tian

“…The concentrations of serum thyroid-stimulating hormone (TSH), TGAb, TPOAb, and B cell activating factor (BAFF) were detected in each group by enzyme-linked immunosorbent assay (ELISA), and the expression of interleukin-10 (IL-10) in thyroid tissue was detected by immunohistochemistry. …”
Get full text

Long COVID in transgender and gender nonbinary people in the United States by Andrea L. Wirtz, Sari L. Reisner, S. Wilson Cole, Darya Adams, J. D. Davids, Alison K. Cohen, Carter Brown, Marissa Miller, Tonia C. Poteat

“…There was no evidence of an association with reported hormone therapy, supporting current recommendations that prioritize gender-affirming care during treatment for long COVID. …”
Get full text

黄体生成素β亚基Trp8Arg和Ile15Thr突变与多囊卵巢综合征 by 张二红, 梁晓燕, 曾海涛, 杜静, 骆春启, 庄广伦

“…【目的】探讨黄体生成素(luteinizing hormone,LH)β亚基Trp8Arg和Ile15Thr突变与中国人多囊卵巢综合征(polycystic ovary syndrome,PCOS)的关系。…”
Get full text

Mesenchymal stem cells enchanced by salidroside to inhibit ferroptosis and improve premature ovarian insufficiency via Keap1/Nrf2/GPX4 signaling by Lixuan Chen, Yingnan Wu, Tiying Lv, Rui Tuo, Yang Xiao

“…However, the efficacy of MSCs is still limited.Purpose This study aims to explain whether salidroside and MSCs combination is a therapeutic strategy to POI and to explore salidroside-enhanced MSCs inhibiting ferroptosis via Keap1/Nrf2/GPX4 signaling.Methods The effect of salidroside and MSCs on ovarian granular cells (GCs) was analyzed. After treatment, hormone levels and -fertility of rats were measured. …”
Get full text

Prevalence of Hypercalcaemia in a Renal Transplant Population: A Single Centre Study by Tony Amin, P. Toby Coates, Jeffrey Barbara, Paul Hakendorf, Nazmul Karim

“…Hypercalcaemia in the renal transplant population was not secondary to suboptimal allograft function but secondary to pretransplantation hyperparathyroidism with persistent high parathyroid hormone (PTH) levels after transplantation. Conclusion. …”
Get full text

Gender Differences in Ghrelin Association with Cardiometabolic Risk Factors in Arab Population by Mohamed Abu-Farha, Mohammed Dehbi, Fiona Noronha, Ali Tiss, Monira Alarouj, Kazem Behbehani, Abdullah Bennakhi, Naser Elkum

“…Ghrelin is a stomach produced hormone that has been shown to have protective role against development of CVD which is a leading cause of death in the Arab world. …”
Get full text

A Rare Presentation of Primary Hyperparathyroidism with Concurrent Aldosterone-Producing Adrenal Carcinoma by Mario Molina-Ayala, Claudia Ramírez-Rentería, Analleli Manguilar-León, Pedro Paúl-Gaytán, Aldo Ferreira-Hermosillo

“…Biochemical assessment showed a mildly elevated calcium (11.1 mg/dL), high parathyroid hormone, and a plasma aldosterone concentration/plasma renin activity ratio of 124.5 (normal < 30), compatible with primary hyperparathyroidism with a concomitant primary hyperaldosteronism. …”
Get full text

Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

“…The identified risk factors for thyroid irAEs include the presence of thyroid autoantibodies, thyroid uptake on 18F-FDG-PET, prior use of tyrosine kinase inhibitors (TKIs), high BMI and high thyroid-stimulating hormone levels. There is evidence that overt thyroid irAEs are associated with good prognosis, at least in non-small cell lung cancer. …”
Get full text

Effect of autologous platelet-rich plasma treatment on patients with thin endometrium by Tung Nguyen Thanh, Ai Hoang Van, Son Trinh The, Lan Do Ngoc, Hang Doan Thi, Trang Quan Van, Khoa Ba Tran, Sang Trieu Tien

“…Methods: In 34 patients with thin endometrium (< 7 mm), canceled in the previous frozen embryo transfer cycles, autologous platelet-rich plasma was prepared, from autologous peripheral vein blood; intrauterine infusion was given during hormone replacement therapy in frozen embryo transfer cycles. …”
Get full text