Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis by Huan Han, Hanwen Su, Zhihua Lv, Chengliang Zhu, Jingtao Huang

“…The treatment of it is currently based on surgical removal, radiotherapy, and hormone therapy. It is crucial to improve therapeutic prospects for the diagnosis and treatment of prostate cancer via drug target screening. …”
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A Nonfunctioning Pituitary Macroadenoma Presenting as Cyclical Vomiting and Severe Hyponatremia in a Young Female by Dinuka S. Warapitiya, Dimuthu Muthukuda, W. A. H. P. Sanjeewa, Kushalee Poornima Jayawickreme, Shyama Subasinghe

“…Nonfunctioning pituitary macroadenomas generally present with visual disturbances, headache, and symptoms due to anterior pituitary hormone deficiencies. This case report is about an atypical presentation of a nonfunctioning pituitary macroadenoma in which the patient presented with cyclical vomiting with severe hyponatremia. …”
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Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats by Emmanuel Nnaemeka Uhuo, Simeon Ikechukwu Egba, Chiemeziem Adnma Obike, Paul Ndubuisi Anyiam, Prince Ogochukwu Alaebo, Pryanka Munachiso Okeke, Emmanuella Chinaza Obinali

“…Conclusion: The mechanisms of BPH inhibition involve the regulation of sex hormone levels and the amelioration of conditions caused by oxidative damage. …”
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GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial by Minh Tam Le, Dac Nguyen Nguyen, Jessica Zolton, Vu Quoc Huy Nguyen, Quang Vinh Truong, Ngoc Thanh Cao, Alan Decherney, Micah J. Hill

“…This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who are administered either gonadotropin-releasing hormone agonist (GnRHa) or human chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination (IUI) cycles. …”
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Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal by Xinya Li, Zaiwei Song, Yixuan Chen, Jingjing Wu, Dan Jiang, Zhen Zhang, Zeyuan Wang, Rongsheng Zhao

“…Results The systematic review encompassed 21 observational studies involving 4,145 patients, revealing associations between ICI-TD and factors such as female gender, age, receipt of Pembrolizumab (versus other ICIs), and baseline levels of thyroid-stimulating hormone, free thyroxine, and antithyroid antibodies. …”
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Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study by Mehryar Mehrkash, Seyed-javad Golestaneh, Yahya Madihi, Fatemeh Paknazar, Mahdi Hadian, Mojtaba Akbari, Bahareh Abtahi-Naeini

“…The distribution score of pruritus was directly correlated with the age (Spearman’s rho=0.42, P=0.02) and serum level of parathyroid hormone (PTH) (Spearman’s rho=0.42, P=0.04). In the reduced multiple logistic regression model, the increasing level of serum calcium was associated with increased odds of having total pruritus score≥5 (OR (odds ratio): 4.5; 95% CI 1.12 to 18.05). …”
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Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy by Shogo Hosogoe, Osamu Soma, Teppei Matsumoto, Atsushi Imai, Shingo Hatakeyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Chikara Ohyama, Masahiko Aoki

“…The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. …”
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Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum by Alessandra Puddu, Roberta Sanguineti, Arianna Durante, Alessio Nencioni, François Mach, Fabrizio Montecucco, Giorgio L. Viviani

“…Glucagon-like peptide-1 (GLP-1), an incretin hormone that regulates glucose homeostasis, might counteract the harmful effects of AGEs on the beta cells in culture. …”
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Urine metabolic profile in rats with arterial hypertension of different genesis by A. A. Sorokoumova, A. A. Seryapina, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, М. А. Gilinsky, А. L. Markel

“…To identify metabolomic markers for hypertensive conditions of different origins, three forms of arterial hypertension (AH) were studied: rats with hereditary AH (ISIAH rat strain); rats with AH induced by L-NAME administration (a model of endothelial dysfunction with impaired NO production); rats with AH caused by the administration of deoxycorticosterone in combination with salt loading (hormone-dependent form – DOCAsalt AH). WAG rats were used as normotensive controls. 24-hour urine samples were collected from all animals and analyzed by quantitative NMR spectroscopy for metabolic profiling. …”
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Genetic basis of depressive disorders by Yu. D. Davydova, R. F. Enikeeva, A. V. Kazantseva, R. N. Mustafin, A. R. Romanova, S. B. Malykh, E. K. Khusnutdinov

“…In addition, there is evidence of the involvement of HPA-axis genes (OXTR, AVPR1A, and AVPR1B), sex hormone receptors genes (ESR1, ESR2, and AR), neurotrophin (BDNF) and methylenetetrahydrofolate reductase (MTHFR) genes, neuronal apoptosis (CASP3, BCL-XL, BAX, NPY, APP, and GRIN1) and inflammatory system (TNF, CRP, IL6, IL1B, PSMB4, PSMD9, and STAT3) genes in DD development. …”
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Risk Factors Associated with Breast Cancer in Women in a Health Area by Naifi Hierrezuelo Rojas, Mileidy Cordoví Hierrezuelo, Naiovis Neira Hierrezuelo

“…Breast cancer was considered as the dependent variable; the following were used as independent variables: age, personal and family pathological history, early menarche, late menopause, nulliparity, age of the first child, exclusive breastfeeding, replacement or replacement hormone therapy, use of contraceptive methods, obesity, sedentary lifestyle, smoking, alcoholism. …”
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The correlation between the expression of androgen receptor splice variant-7 (AR-V7) protein with the time of occurrence of castration-resistant prostate cancer and overall surviva... by Indrawarman Soerohardjo, Narpati Wesa Pikatan, Andy Zulfiqqar, Irianiwati Widodo, Didik Setyo Heriyanto

“…Abstract Introduction Prostate cancer follows a natural trajectory characterized by genetic alterations that transform initially hormone-sensitive cancer cells into castration-resistant prostate cancer (CRPC), which is associated with high mortality. …”
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False Positive Radioiodinated Metaiodobenzylguanidine (123I-MIBG) Uptake in Undifferentiated Adrenal Malignant Tumor by Hee Soo Jung, Seok Jun Moon, Yun Mi Kim, Hye Rim Kang, Seok Mo Lee, Soo Jin Jung, Seok Jin Choi, Tae Kyoon Kim, Min Jeong Kwon, Jeong Hyun Park, Soon Hee Lee

“…Abdominal computed tomography (CT) revealed a heterogeneous left adrenal mass 6 cm in diameter; following hormone testing, 123I-MIBG scintigraphy was performed to determine the presence of pheochromocytoma, which confirmed eccentric uptake by a large left adrenal gland mass. …”
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The role of salivary antioxidant level in polycystic ovary syndrome women under assisted reproductive technology treatment: A case-control study by Narges Gholizadeh, Maryam Koopaie, Ashraf Aleyasin, Atousa Mortazavi Milani, Marziyeh Aghahosseini, Mohammad Javad Kharrazifard, Mohadeseh Bahmaee

“…Serum and salivary antioxidant levels such as saliva superoxide dismutase (SOD), saliva anti-Müllerian hormone (AMH), serum SOD, serum total oxidant status, and serum AMH were measured. …”
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Diagnostic and Prognostic Impact of Progesterone Receptor Immunohistochemistry: A Study Evaluating More Than 16,000 Tumors by Florian Viehweger, Lisa-Marie Tinger, David Dum, Natalia Gorbokon, Anne Menz, Ria Uhlig, Franziska Büscheck, Andreas M. Luebke, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Christoph Fraune, Patrick Lebok, Sören Weidemann, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Rainer Krech, Till Krech, Andreas H. Marx, Ronald Simon, Eike Burandt, Stefan Steurer, Guido Sauter, Sarah Minner, Christian Bernreuther

“…Progesterone receptor (PR) is a member of the nuclear/steroid hormone receptor family of ligand-dependent transcription factors. …”
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Pembrolizumab with external radiation therapy effectively controlled TMB-high unresectable recurrent parathyroid cancer: a case report with review of literature by Hiroshi Katoh, Tomoya Mitsuma, Riku Okamoto, Kanako Naito, Takaaki Tokito, Mariko Kikuchi, Takafumi Sangai

“…Parathyroid cancer (PC) is extremely resistant to chemotherapy and radiotherapy (RT), but hormonally functional by producing excessive parathyroid hormone (PTH), causing remarkable hypercalcemia even in biochemical disease recurrence. …”
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Lighting quality evaluation on growth performance and feather pecking behavior of broilers by Chenghao Pan, Rong Xiang, Jinming Pan

“…To evaluate the quality of lighting in production of a local broiler breed, this study was designed to investigate the effects of light color on the growth performance (body weight, feed conversion ratio and upper beak length), welfare parameters (walking step, plumage damage and hormone level) relating to feather pecking and their correlations. …”
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Characteristics Associated with Acute-Phase Response following First Zoledronic Acid Infusion in Brazilian Population with Osteoporosis by Bruno S. A. Ferreira, Bernardo M. da Cunha, Luciana P. Valadares, Larissa A. Moreira, Frederico G. A. Batista, Cristiane da F. Hottz, Marina M. P. Lins, Gabriel G. R. Magalhães, Luanna M. de Arruda, Sergio H. R. Ramalho

“…Clinical demographics (age, sex, diabetes, smoking, body mass index, and previous oral bisphosphonate use) and laboratory data (calcium, parathyroid hormone, renal function, and serum 25-hydroxyvitamin D and carboxy-terminal crosslinked telopeptide of type 1 collagen [CTX], both before and after infusion) were compared between patients with and without APR. …”
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Total Parathyroidectomy with Subcutaneous Parathyroid Forearm Autotransplantation in the Treatment of Secondary Hyperparathyroidism: A Single-Center Experience by Claudio Casella, Alessandro Galani, Luigi Totaro, Silvia Ministrini, Silvia Lai, Mira Dimko, Nazario Portolani

“…Parathyroidectomy is indicated in refractory hyperparathyroidism when medical treatments and so the parathyroid hormone levels cannot be lowered to acceptable values without causing significant hyperphosphatemia or hypercalcemia. …”
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Effect of Exogenous Melatonin on the Quality of Soybean and Natto Products under Drought Stress by Liang Cao, Fang Kou, Mingcong Zhang, Xijun Jin, Chunyuan Ren, Gaobo Yu, Yuxian Zhang, Mengxue Wang

“…Melatonin can directly or indirectly eliminate reactive oxygen species, regulate hormone levels, and improve drought-stressed soybean crop resistance, yield, and quality. …”
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