-
1201
A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte
Published 2017-01-01“…IL-1β is a strong regulator of Brain Natriuretic Peptide (BNP), a hormone involved in cardiovascular homeostasis by guanylyl cyclase Natriuretic Peptide Receptor (NPR-1). …”
Get full text
Article -
1202
A New Hope for the Patients of Non‐Alcoholic Steatohepatitis: FDA Gives Green Signal for Resmetirom Use
Published 2025-01-01“…Recently, resmetirom, a thyroid hormone receptor‐β agonist, received FDA approval for treating NASH, offering new hope to patients. …”
Get full text
Article -
1203
Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer?
Published 2025-01-01“…In breast cancer, AR exhibits diverse functions across subtypes, often interacting with other hormone receptors, thereby influencing tumor progression and treatment responses. …”
Get full text
Article -
1204
Impact of Resistance Exercise under Hypoxia on Postexercise Hemodynamics in Healthy Young Males
Published 2018-01-01“…The MAP at 20 and 30 min of recovery in hypoxia was significantly lower than in normoxia (P < 0.05, respectively). The antidiuretic hormone significantly increased after 60 min of recovery in both conditions; moreover, the values in hypoxia were significantly higher than those in normoxia (P < 0.05). …”
Get full text
Article -
1205
The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Releva...
Published 2013-01-01“…The gut-brain-adipose tissue (AT) peptides and neutralizing autoantibodies play an important role in the regulation of eating behavior and growth hormone release. The mechanisms for controlling food intake involve an interplay between gut, brain, and AT. …”
Get full text
Article -
1206
Thyroid-Disrupting Activities of Groundwater from a Riverbank Filtration System in Wuchang City, China: Seasonal Distribution and Human Health Risk Assessment
Published 2020-01-01“…The recombinant thyroid hormone receptor (TR) gene yeast assay was used to evaluate thyroid disruption caused by groundwater from the riverbank filtration (RBF) system in Wuchang City, China. …”
Get full text
Article -
1207
Biological Characteristics and Medical Treatment of Breast Cancer in Young Women—A Featured Population: Results from the NORA Study
Published 2011-01-01“…Positive nodal status, large tumors, and elevated Ki67 all associated with the choice for chemotherapy followed by endocrine therapy in hormone receptor-positive patients (𝑃<.0001). At univariate analysis, ER-ve status, chemotherapy and age resulted as the only statistically significant variables (HR=2.02, 𝑃=.004, and >40 versus ≤40, 𝑃<.0001, resp.). …”
Get full text
Article -
1208
Cangfudaotan Decoction Alleviates Insulin Resistance and Improves Follicular Development in Rats with Polycystic Ovary Syndrome via IGF-1-PI3K/Akt-Bax/Bcl-2 Pathway
Published 2020-01-01“…CFD was able to improve IR, restore the serum hormone levels, inhibit the inflammatory cytokines in PCOS rat, and alleviate ovary morphological injury and apoptosis in PCOS rats. …”
Get full text
Article -
1209
Effects of Selenium Supplement on B Lymphocyte Activity in Experimental Autoimmune Thyroiditis Rats
Published 2021-01-01“…The concentrations of serum thyroid-stimulating hormone (TSH), TGAb, TPOAb, and B cell activating factor (BAFF) were detected in each group by enzyme-linked immunosorbent assay (ELISA), and the expression of interleukin-10 (IL-10) in thyroid tissue was detected by immunohistochemistry. …”
Get full text
Article -
1210
Mesenchymal stem cells enchanced by salidroside to inhibit ferroptosis and improve premature ovarian insufficiency via Keap1/Nrf2/GPX4 signaling
Published 2025-12-01“…However, the efficacy of MSCs is still limited.Purpose This study aims to explain whether salidroside and MSCs combination is a therapeutic strategy to POI and to explore salidroside-enhanced MSCs inhibiting ferroptosis via Keap1/Nrf2/GPX4 signaling.Methods The effect of salidroside and MSCs on ovarian granular cells (GCs) was analyzed. After treatment, hormone levels and -fertility of rats were measured. …”
Get full text
Article -
1211
Prevalence of Hypercalcaemia in a Renal Transplant Population: A Single Centre Study
Published 2016-01-01“…Hypercalcaemia in the renal transplant population was not secondary to suboptimal allograft function but secondary to pretransplantation hyperparathyroidism with persistent high parathyroid hormone (PTH) levels after transplantation. Conclusion. …”
Get full text
Article -
1212
Gender Differences in Ghrelin Association with Cardiometabolic Risk Factors in Arab Population
Published 2014-01-01“…Ghrelin is a stomach produced hormone that has been shown to have protective role against development of CVD which is a leading cause of death in the Arab world. …”
Get full text
Article -
1213
A Rare Presentation of Primary Hyperparathyroidism with Concurrent Aldosterone-Producing Adrenal Carcinoma
Published 2015-01-01“…Biochemical assessment showed a mildly elevated calcium (11.1 mg/dL), high parathyroid hormone, and a plasma aldosterone concentration/plasma renin activity ratio of 124.5 (normal < 30), compatible with primary hyperparathyroidism with a concomitant primary hyperaldosteronism. …”
Get full text
Article -
1214
Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors
Published 2025-01-01“…The identified risk factors for thyroid irAEs include the presence of thyroid autoantibodies, thyroid uptake on 18F-FDG-PET, prior use of tyrosine kinase inhibitors (TKIs), high BMI and high thyroid-stimulating hormone levels. There is evidence that overt thyroid irAEs are associated with good prognosis, at least in non-small cell lung cancer. …”
Get full text
Article -
1215
Impact of headache in women with polycystic ovary syndrome
Published 2021-12-01“…Participants were tested for complete blood count, fasting glucose, fasting insulin, lipid profile, and comprehensive hormone panel. An ad-hoc questionnaire was given to the participants to obtain information on headache. …”
Get full text
Article -
1216
Interpretable Machine Learning Model for Predicting Postpartum Depression: Retrospective Study
Published 2025-01-01“…Shapley Additive Explanation indicated that the most influential predictors of PPD were antepartum depression, lower fetal weight, elevated thyroid-stimulating hormone, declined thyroid peroxidase antibodies, elevated serum ferritin, and older age. …”
Get full text
Article -
1217
Review of osteokines in spinal cord injury: potential biomarkers during rehabilitation
Published 2025-01-01“…Abstract After spinal cord injury (SCI), mechanical unloading, denervation, as well as negative changes in blood supply, inflammation state, and hormone levels produce significant negative effects on bone density, leading to a high prevalence of osteoporosis after SCI. …”
Get full text
Article -
1218
Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature
Published 2020-01-01“…He came to our attention due to an increase in calcium and parathyroid hormone serum levels. Neck ultrasound (US) showed a solid hypodense mass, probably the right inferior parathyroid gland, with an estimated size of 25 × 15 × 13 mm; the 99mTc-sestamibi SPECT/CT scan revealed a large radiotracer activity area in the right cervical region, compatible with a hyperfunctioning right inferior parathyroid gland. …”
Get full text
Article -
1219
Comprehensive characterization of platelet function in dogs with hyperadrenocorticism
Published 2025-02-01“…In addition, 2-MeSADP- and thrombininduced platelet aggregation and post-adrenocorticotropic hormone (ACTH) cortisol levels showed a negative correlation. …”
Get full text
Article -
1220
Rapid changes in plasma corticosterone and medial amygdala transcriptome profiles during social status change reveal molecular pathways associated with a major life history transit...
Published 2025-01-01“…Two genes, Myosin binding protein C1 (Mybpc1) and μ-Crystallin (Crym), associated with vasoactive intestinal polypeptide (VIP) and thyroid hormone pathways respectively, are highly upregulated in socially transitioning individuals. …”
Get full text
Article