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1061
Reprogramming of Mice Primary Hepatocytes into Insulin-Producing Cells by Transfection with Multicistronic Vectors
Published 2014-01-01“…These triple-transfected cells activated multiple beta-cell genes, synthesized and stored considerable amounts of insulin, and released the hormone in a glucose-regulated manner in vitro. Furthermore, when transplanted into streptozotocin-induced diabetic mice, the cells markedly ameliorated glucose tolerance. …”
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1062
Lithium as an Alternative Option in Graves Thyrotoxicosis
Published 2015-01-01“…High dose Hydrocortisone and propranolol were also administered concomitantly. Free thyroid hormone levels decreased and the patient reached a biochemical and clinical euthyroid state in about 8 days. …”
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1063
Distinct vaginal microbiome and metabolome profiles in women with preterm delivery following cervical cerclage
Published 2025-02-01“…In addition, vaginal metabolomics-based liquid chromatography–Orbitrap–tandem mass spectrometry (LC-Orbitrap-MS/MS) found that the alteration in vaginal metabolites in pregnant women with PTB is involved in starch and sucrose metabolism; arginine and praline metabolism; galactose metabolism; purine metabolism; arginine metabolism; tryptophan metabolism and N-glycan biosynthesis; cysteine and methionine metabolism; taurine and hypotaurine metabolism; amino acid metabolism; propanoate metabolism; valine, leucine, and isoleucine biosynthesis; glycine, serine, and threonine metabolism; and steroid hormone biosynthesis. These results elaborated that distinct vaginal microbiome and metabolome profiles in women with preterm delivery following cervical cerclage provide valuable information for establishing the prediction models for PTB.…”
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1064
Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital—
Published 2024-01-01“…The most important factor predicting PTMC growth is young age, and PTMC enlargement in young patients may be affected by high serum levels of thyroid-stimulating hormone. This review notes that one patient showed lung metastasis after conversion surgery (CS) following AS, but there are no reports of patients dying of thyroid carcinoma during or after AS. …”
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1065
Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer
Published 2012-01-01“…The peroxisome proliferator-activated receptor-gamma (PPARγ) is a member of the hormone-activated nuclear receptor superfamily. PPARγ can be activated by a diverse group of agents, such as endogenous polyunsaturated fatty acids, 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2), and thiazolidinedione (TZD) drugs. …”
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1066
Stress Hyperglycemia, Insulin Treatment, and Innate Immune Cells
Published 2014-01-01“…Hyperglycemia (HG) and insulin resistance are the hallmarks of a profoundly altered metabolism in critical illness resulting from the release of cortisol, catecholamines, and cytokines, as well as glucagon and growth hormone. Recent studies have proposed a fundamental role of the immune system towards the development of insulin resistance in traumatic patients. …”
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1067
Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b
Published 2022-01-01“…Progesterone (P4) is widely used in hormone therapy to support pregnancy, but little is known about its effects on maternal cardiac function. …”
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1068
Effects of Obesity on Bone Mass and Quality in Ovariectomized Female Zucker Rats
Published 2014-01-01“…These findings demonstrated that ovarian hormone deficiency adversely affected bone mass and quality in lean and obese rats while obesity only affected Tb.Th in Ovx-female Zucker rats.…”
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1069
Improvement of Hypertension after Parathyroidectomy of Patients Suffering from Primary Hyperparathyroidism
Published 2011-01-01“…We evaluated changes in serum calcium, parathyroid hormone (PTH), uric acid, and BP before and 6 months after surgery. …”
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1070
Network analysis uncovers the master role of WRKY transcription factors in Arabidopsis thaliana response to N-acyl homoserine lactones
Published 2024-01-01“…Even though the benefits conferred by AHL depend on various hormone signaling pathways, the understanding of AHL signaling, especially the response to AHL presence, remains largely unknown. …”
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1071
An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes
Published 2013-01-01“…Glucagon-like peptide-1 (GLP-1) is a gut hormone produced in the intestinal epithelial endocrine L cells by differential processing of the proglucagon gene. …”
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1072
Value of Biochemical Indexes of Bone Metabolism in Predicting Osteoporotic Lumbar Fractures
Published 2022-01-01“…To investigate the value of bone metabolism indexes such as type I procollagen N-terminal propeptide (P1NP), 25-hydroxyvitamin D (25(OH)D), osteocalcin (OSTEOC), and parathyroid hormone (PTH) in predicting osteoporotic lumbar fractures. …”
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1073
Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
Published 2013-12-01“…RESULTS: No significant difference was found between pregnant and non-pregnant groups regarding the AFC, hormone and controlled ovarian hyperstimulation (COH) parameters (total dose of gonadotrophins (1995.7±851.1 vs 2296.4±845.3 IU), >14 mm follicles (9.3±3.1 vs 7.3±3.9), retrieved oocytes (12.4±5.1 vs 8.7±6.1) or number of good quality embryos (7.4±3.7 vs 4,4±3.6) (p>0.05). …”
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1074
Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma in the Same Patient as a Collision Tumour
Published 2019-01-01“…Physical examination revealed 2 cm nodule on the thyroid right lobe. Serum thyroid hormone levels were within normal range. Ultrasonography revealed a 23x15 mm hypoechoic nodule with micro calcifications and cystic areas on the right lobe. …”
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1075
The Serum Level of Fibroblast Growth Factor-23 and Calcium-Phosphate Homeostasis in Obese Perimenopausal Women
Published 2011-01-01“…Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D3, CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were assessed. …”
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1076
The Diagnostic Value of Irisin in Pediatric Patients with Acute Abdominal Pain
Published 2018-01-01“…The purpose of this study was to investigate the effectiveness of irisin, a peptide hormone with reactivity shown in the appendix and neutrophils, in the differential diagnosis of pediatric patients with acute abdominal pain. …”
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1077
Transcriptional Profiling of Testis Development in Pre-Sexually-Mature Hezuo Pig
Published 2024-12-01“…Expressed genes in spermatocytes (SPCs) were enriched in the cAMP, cell cycle, male gamete generation, reproductive system development, and sexual reproduction, while growth hormone synthesis, gamete generation, reproductive process, and spermine synthase activity were enriched in Sertoli cells (SCs). …”
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1078
The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation
Published 2013-01-01“…To investigate the endocrine and/or clinical characteristics of women with low anti-Müllerian hormone (AMH) that could improve the accuracy of IVF outcome prediction based on the female age alone prior to the first GnRH antagonist IVF cycle. …”
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1079
Genome-Wide Analysis and Expression Profiling of Watermelon <i>VQ</i> Motif-Containing Genes Under Abiotic and Biotic Stresses
Published 2025-01-01“…Numerous stress- and hormone-responsive <i>cis</i>-elements were detected in the putative promoter region of the <i>ClVQ</i> genes. …”
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1080
Does Hypothyroidism Affect Gastrointestinal Motility?
Published 2009-01-01“…Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism. …”
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