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1001
Molecular Subtypes of Breast Carcinoma and Their Association with Clinicopathological Features
Published 2025-01-01“… Background: Breast cancer is categorized into four primary molecular subtypes based on gene expression profiles and hormone receptor status: Luminal A & B subtypes, Basal-like, and HER2-enriched. …”
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1002
Anabolic androgenic steroids intake and its impact on male reproductive system - systematic review
Published 2025-02-01“…AAS bind to androgen receptors, promoting muscle growth by increasing protein synthesis and promoting the growth hormone-insulin-like growth factor 1 axis. AAS are commonly administered via intramuscular injection or oral ingestion. …”
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1003
Exogenously applied ABA alleviates dysplasia of maize (Zea mays L.) ear under drought stress by altering photosynthesis and sucrose transport
Published 2025-12-01“…Abscisic acid (ABA) is a plant hormone that can regulate the physicology metabolism under abiotic stress. …”
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1004
PPAR Agonists for the Prevention and Treatment of Lung Cancer
Published 2017-01-01“…Recently, a family of nuclear hormone receptors, the peroxisome proliferator-activated receptors (PPARs), has attracted significant attention for its role in various malignancies including lung cancer. …”
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1005
Acromegaly: Role of Surgery in the Therapeutic Armamentarium
Published 2012-01-01“…Somatostatin analogues are included as the first line of medication, followed by dopamine agonist and growth hormone receptors antagonists. Radiation therapy can be also indicated in two main forms for residual tumor with medically refractory patients: radiosurgery for small tumors or fractionated stereotactic radiotherapy for larger ones.…”
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1006
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Published 2025-02-01“…Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased pathological tissue remodeling. …”
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1007
Pathology of the Gastrointestinal Tract in Patients with Primary Hyperparathyroidism
Published 2023-02-01“…Some authors report the impact of elevated parathyroid hormone levels on the formation of gallbladder stones by inhibiting of gallbladder emptying, hepatic bile secretion and mobility of the sphincter Oddi, and changing of the bile composition. …”
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1008
The Effect of Thyroid Dysfunction on the Cardiovascular Risk of Type 2 Diabetes Mellitus Patients in Ghana
Published 2018-01-01“…Positive correlation was found between CHD risk and HbA1c, total cholesterol, low-density lipoprotein cholesterol, systolic blood pressure, and thyroid stimulating hormone. Conclusion. The presence of thyroid dysfunction significantly increased the CHD risk associated with T2DM patients in Ghana.…”
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1009
Melatonin and Angelman Syndrome: Implications and Mathematical Model of Diurnal Secretion
Published 2017-01-01“…The characteristics describing the diurnal hormone secretion such as minimum melatonin concentration, release amplitude, phase shift of melatonin release, and sleep duration as well as the dim light melatonin onset (DLMO) of melatonin secretion and the γ shape parameter allow analyzing the fit and deducing about how much the measured melatonin profile differs from a physiological bell-shaped secretion. …”
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1010
Proposed reference intervals of serum insulin-like growth factor-1 (IGF-1) levels in older Japanese populations
Published 2023-10-01“…Measurements of serum insulin-like growth factor 1 (IGF-1) levels are useful surrogate markers for the diagnosis and management of patients with growth hormone-related disorders. We have previously published normative data of serum IGF-1 levels for the Japanese population aged 0–77 years by combining and analyzing previously reported references, which were separately and independently constructed, to properly reflect data in the transition period. …”
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1011
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers
Published 2025-02-01“…Key differentially expressed genes included CRH(Corticotropin-Releasing Hormone), LEP(Leptin), PDK4(Pyruvate Dehydrogenase Kinase Isozyme 4), SPP1(Secreted Phosphoprotein 1), and SST(Somatostatin). …”
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1012
Melatonin influence on miRNA expression in sperm, hypothalamus, pre-frontal cortex and cerebellum of Wistar rats.
Published 2025-01-01“…Melatonin is a pineal hormone synthesized exclusively at night, in several organisms. …”
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1013
Protocol of an Efficacy Study on Nursing Consultation in Weight Management and Metabolic Syndrome Based on the Carbohydrate–Insulin Theory in Individuals with First-Episode Psychos...
Published 2024-12-01“…The approach to managing this issue has evolved from a focus on calorie counting to a deeper understanding of hormone function, particularly the role of insulin resistance in MetS. …”
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1014
The silent pandemic of stress: impact on menstrual cycle and ovulation
Published 2025-12-01“…Functional hypogonadotropic hypogonadism is a spectrum ranging ranging from regular menstrual cycles with short or insufficient luteal phases to irregular cycles, oligomenorrhea, anovulation, and complete amenorrhea, depending on how stress variably disrupts gonadotropic-releasing hormone (GnRH) drive. Functional hypothalamic amenorrhea (FHA), the most severe manifestation, is a complex global neuroendocrinopathy with several serious health consequences in addition to amenorrhea and infertility. …”
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1015
Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct
Published 2012-01-01“…The plant hormone, ethylene, is an important regulator which involved in regulating fruit ripening and flower senescence. …”
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1016
Thyroid Function after Subtotal Thyroidectomy in Patients with Graves’ Hyperthyroidism
Published 2012-01-01“…Subtotal thyroidectomy is a surgical procedure, in which the surgeon leaves a small thyroid remnant in situ to preserve thyroid function, thereby preventing lifelong thyroid hormone supplementation therapy. Aim. To evaluate thyroid function after subtotal thyroidectomy for Graves’ hyperthyroidism. …”
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1017
A Rare Variation of Transverse Testicular Ectopia (TTE) in a Young Adult as an Incidental Finding during Investigation for Testicular Pain
Published 2018-01-01“…Laboratory tests were significant for elevated follicle-stimulating hormone (FSH), while sperm count revealed azoospermia. …”
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1018
Histological changes of endocervical polypoid lesions in women at reproductive age
Published 2024-01-01“…Materials and Methods: Sixty specimens of the resected cervical polyps were obtained from Al-Salaam Teaching Hospital in Mosul city during the period from June 2021 to February 2022, women diagnosed to have cervical polyps on per speculum examination were given a time to be operated on with exclusion of pregnant, postmenopausal women, those on hormone replacement therapy, and those below 20 years. …”
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1019
Chronic Kidney Disease, Obesity, and Hypertension: The Role of Leptin and Adiponectin
Published 2012-01-01“…Remarkable improvements have been recently achieved in the study of the endocrine features of the adipose tissue and have been able to produce hormone-like peptides named adipokines or adipocytokines. …”
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1020
Late Endocrine Effects after Stem Cell Transplant in a Young Girl with Griscelli Syndrome
Published 2021-01-01“…She started spontaneous puberty; however, initial biochemical evaluation revealed hypergonadotropic hypogonadism with undetectable anti-Mullerian hormone (AMH) consistent with low ovarian reserve and premature ovarian failure. …”
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