Gender, FT4 levels, T stage, and BMI as predictors of TSH levels in thyroid cancer patients by Sen Zhang, Shuli Niu, Ling Zhou

“…BackgroundAfter initial treatment, levothyroxine (LT4) administration is necessary for thyroid cancer patients to achieve target thyroid-stimulating hormone (TSH) levels. However, the clinical efficacy of weight-based LT4 dosing has been suboptimal, highlighting the need to identify factors influencing the attainment of desired TSH levels and guide personalized treatment.MethodsWe constructed a retrospective cohort comprising 215 patients diagnosed with thyroid cancer. …”
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The protective effects of active ingredients from acrorus tatarinowii on sperm and their molecular mechanisms by Zonglin Lu, Haiyang Zhao, Hui Wang, Xin Wang, Zixue Sun

“…Methods Initially, using the TCMSP and Disgenet databases, active ingredients of Acrorus tatarinowii were identified and their target genes associated with sperm-related diseases were elucidated.Subsequently, an oligoasthenozoospermia mouse model was induced and treated with Acrorus tatarinowii. Serum hormone levels were assessed by ELISA, testicular histopathology by HE staining, and target gene expression by qPCR and Western blotting. …”
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THERAPY FOR IRREGULAR MENSTRUATION WITH ACUPUNTURE AND HERBAL PEGAGAN (CENTELLA ASIATICA (L.)) by Evin Dwi Prayuni, Ario Imandiri, Myrna Adianti

“…Menstruation bleeding is complex interaction result wich involve hormone system and body system, that are hypothalamus, hypofisis, ovarium and uterus. …”
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Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome by Mimouni, Nour El Houda, Giacobini, Paolo

“…However, the underlying mechanisms of its transmission remain unknown, thus limiting the development of effective therapeutic strategies.This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.…”
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Effects of Long Distance Transportation on Honey Bee Physiology by Kiheung Ahn, Xianbing Xie, Joseph Riddle, Jeff Pettis, Zachary Y. Huang

“…There were no significant differences between S and T colonies in juvenile hormone titers. Protein content in head showed no significant differences between S and T either in 7-day-old or 17-day-old bees of MI trial, but GA trial showed a significant reduction in bees experiencing transportation. …”
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The role of insulin signaling with FOXO and FOXK transcription factors by Masaji Sakaguchi

“…Insulin is an essential hormone for animal activity and survival, and it controls the metabolic functions of the entire body. …”
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Antifibrotic Activity of Acylated and Unacylated Ghrelin by Elia Angelino, Simone Reano, Michele Ferrara, Emanuela Agosti, Andrea Graziani, Nicoletta Filigheddu

“…The acylated form, through its receptor GHSR-1a, stimulates appetite and growth hormone (GH) release. Although unacylated ghrelin does not bind or activate GHSR-1a, it shares with the acylated form several biological activities. …”
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FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management by Muhammad Mazhar Azam, Sameen Mukhtar, Muhammad Haris, Fatima Laique, Suhaina Amir, Mubashir Mohiuddin, Bibek Giri

“…MASH is a growing global health concern, and resmetirom offers a novel therapeutic option by targeting liver pathophysiology through thyroid hormone receptor-beta activation. This mechanism effectively reduces fibrosis markers, improves liver enzyme levels, and minimizes liver fat buildup. …”
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Synthesis and Biological Evaluation of New CRH Analogues by Spyridon Papazacharias, Vassiliki Magafa, Nicole Bernad, George Pairas, Georgios A. Spyroulias, Jean Martinez, Paul Cordopatis

“…A series of 7 new human/rat Corticotropin Releasing Hormone (h/r-CRH) analogues were synthesized. The induced alterations include substitution of Phe at position 12 with D-Phe, Leu at positions 14 and 15 with Aib and Met at positions 21 and 38 with Cys(Et) and Cys(Pr). …”
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Targeting Bone Metabolism in Patients with Advanced Prostate Cancer: Current Options and Controversies by Tilman Todenhöfer, Arnulf Stenzl, Lorenz C. Hofbauer, Tilman D. Rachner

“…Maintaining bone health remains a clinical challenge in patients with prostate cancer (PC) who are at risk of developing metastatic bone disease and increased bone loss due to hormone ablation therapy. In patients with cancer-treatment induced bone loss (CTIBL), antiresorptive agents have been shown to improve bone mineral density (BMD) and to reduce the risk of fractures. …”
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The glucocorticoid hypothesis of depression: history and perspectives by G. T. Shishkina, N. N. Dygalo

“…Although the increase in hormone levels following a short-term intervention is directed towards rapid mobilization of the body’s efforts for overcoming potentially dangerous situation, a long-term exposure to stress or glucocorticoids may have negative consequences for mood or behavior. …”
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Recurrent Hydatidiform Moles: A Clinical Challenge—A Case Report and an Update on Management and Therapeutical Strategies by S. Riccio, F. Galanti, M. Scudo, L. Di Troia, M. G. Ferrillo, F. Manzara, P. Ianiri, F. A. Battaglia

“…After the return to the baseline values of the beta-human chorionic gonadotropin hormone, a combined oral contraceptive therapy was proposed, and the patient was invited to undergo in vitro fertilization (IVF) techniques, specifically oocyte donation, to reduce the possibility of similar future cases of RHMs. …”
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SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient by Abbas Agaimy, Deike Strobel, Thomas Strecker

“…The serum parathyroid hormone-related protein (PTHrp) was significantly elevated (241 pg/ml; reference value < 57). …”
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Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation by Adam Aguirre, Carola J. Maturana, Paloma A. Harcha, Juan C. Sáez

“…The corticotropin-releasing hormone and glucocorticoids are critical players in stress-induced mastocyte degranulation and potentiation of glial inflammatory responses, respectively. …”
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Development of the anterior pituitary: diverse lineages of the stem/progenitor cells by Yukio Kato, Takako Kato

“…Differentiation of endocrine cells in the pituitary gland leads to hormone synthesis, secretion into the capillary network, and transportation to target organs. …”
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Genome-wide analysis and characterization of TPD1 family proteins in pearl millet (Cenchrus americanus): Insights into reproductive regulation and phytohormone responses. by Zainab M Almutairi

“…Treatment with phytohormones showed that the expression of CaTPD1s was repressed by hormone treatments except CaTPD1_Ch4.1 and CaTPD1_Ch4.3 which are highly expressed in response to brassinolide and auxin, respectively. …”
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Serum Analysis in Patients with Temporomandibular Disorders: A Controlled Cross-Sectional Study in Norway by Kordian Staniszewski, Henning Lygre, Trond Berge, Annika Rosén

“…To evaluate essential proteins, hormones, electrolytes, and vitamins in serum from TMD patients, a standard blood sample analysis was performed in 60 TMD patients and 60 healthy controls matched for age and gender, retrieving 19 different analyses. …”
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Charge-Based Inhibitors of Amylin Fibrillization and Toxicity by Sharadrao M. Patil, Andrei T. Alexandrescu

“…To test the hypothesis that electrostatic repulsion is an important force opposing amyloid fibril assembly, we designed peptides that substitute strings of positively or negatively charged residues into the sequence of the amyloidogenic hormone amylin, which contributes to type 2 diabetes pathology. …”
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Prostate Cancer-Associated Disseminated Intravascular Coagulation with Excessive Fibrinolysis Treated with Degarelix by Shawn Y. Ong, Josephine Taverna, Clint Jokerst, Thomas Enzler, Emad Hammode, Elisa Rogowitz, Myke R. Green, Hani M. Babiker

“…We describe a case of DIC XFL caused by prostate cancer (PC) successfully treated with a single injection of degarelix, a gonadotropin-releasing hormone (GnRH) receptor antagonist. This led to prompt control of the patient’s coagulopathy within ten days of treatment. …”
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Spontaneous Regression of Uterine Arteriovenous Malformations with Conservative Management by Keiko Mekaru, Sugiko Oishi, Kozue Akamine, Chiaki Heshiki, Yoichi Aoki

“…If estradiol was >300 pg/mL when AVM was diagnosed, then a gonadotropin-releasing hormone agonist was administered. All three women underwent follow-up observation, revealing spontaneous mass disappearance. …”
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