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2601
Investigating the needs and barriers for prevention, control, and treatment of HIV/AIDS in transgender population: a systematic review of literature
Published 2024-09-01“…From the perspective of transgender people, the need for more care and attention after surgery, such as access to appropriate therapeutic hormones and disposable syringes, were more important. …”
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2602
Genome-wide characterization of the MADS-box gene family in Paeonia ostii and expression analysis of genes related to floral organ development
Published 2025-01-01“…Analysis of the cis-acting elements revealed that the 110 PoMADS genes contained different kinds of hormones and stress-related cis-acting elements in their promoter regions. …”
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2603
Decoding mutational signatures in breast cancer: Insights from a multi-cohort study
Published 2025-03-01“…Purpose: Diagnosis and treatment decisions of hormonal breast cancers (BC) are now guided by genomic mutations determination, combined into mutational signatures, and provide insight into the patients’ genomic landscape. …”
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2604
Gonadal aspects, testosterone and estradiol profiles of the Lebranche mullet Mugil liza subjected to different temperatures during the larviculture phase
Published 2025-02-01“…The present study evaluated the influence of different temperatures during Mugil liza larviculture and their late effects on gonadal development and hormonal quantification after 24 months. The fertilized eggs (45 eggs L-1) were initially kept in a 60 L circular tank until hatching. …”
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2605
Stress during Lactation Induces Insulin Resistance Associated with an Increase in Type 1 Cannabinoid Receptors in Liver and Adipose Tissue
Published 2019-01-01“…Several reports have shown that stress during lactation causes long-term metabolic and hormonal disruptions. In this study, we designed experiments to evaluate the effects of stress during lactation on the abundance of Type 1 cannabinoid/endocannabinoid receptors (CB1R) in epididymal fat and liver and development of insulin resistance in adult mice. …”
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2606
Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese
Published 2025-01-01“…The results of this study showed that during the broody period, geese exhibited degraded ovarian tissues, disrupted follicular development, a thinner granulosa cell layer, and lower levels of ovarian hormones E2, P4, and AMH. Antioxidant activity (GSH, CAT, SOD, T-AOC, and the content of H<sub>2</sub>O<sub>2</sub>) and the mRNA expression levels of antioxidant genes (GPX, SOD-1, SOD-2, CAT, COX-2, and Hsp70) were significantly higher in pre-broody geese compared to laying geese, while the expression of apoptosis-related genes (p53, Caspase-3, and Caspase-9) increased and the anti-apoptotic gene Bcl-2 decreased. …”
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2607
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women
Published 2017-01-01“…On this basis, we aimed to investigate the potential association between TRAIL and adipokine levels in a cohort of subjects in which age/gender/hormonal interferences were excluded. Methods. Serum levels of TRAIL and a panel of adipokines were measured in postmenopausal women (n=147) stratified according to waist circumference measures as normal, overweight, or obese. …”
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2608
Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency
Published 2014-01-01“…Here, we describe the molecular genetics of two previously reported male siblings in whom diagnosis of 11β-OHD has been established based on their hormonal profiles displaying high levels of 11-deoxycortisol and hyperandrogenism. …”
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2609
Alarming rise in prevalence of obesity among children with essential hypertension: Reflection of larger global epidemiological change of adolescent nutritional status
Published 2025-03-01“…Details of diagnostic evaluations conducted, comprising blood tests, imaging studies, and hormonal analyses were analyzed. Results: The prevalence of hypertension among the admitted children during the study period was found to be 1.6 %. …”
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2610
Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development
Published 2024-12-01“…CaPINs encompass a multitude of elements associated with growth, environmental responses, and hormonal signaling. Transcriptome data analysis revealed that the expression of CaPINs in pepper was tissue-specific. …”
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2611
The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice
Published 2025-01-01“…This observation calls for further investigation into the mechanisms regulating the actions of glucosinolate hydrolysis products, their interactions with sex hormones, and the determination of permissible intake levels associated with both beneficial and adverse outcomes.…”
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2612
Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer
Published 2025-01-01“…The integrin-linked kinase (ILK) gene has been identified as an oncogenic driver in hormonal cancers, including PCa. Methods To identify key genes in PCa, we utilized differential gene expression analysis and Weighted Gene Co-expression Network Analysis (WGCNA). …”
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2613
Inverse Relationship Between Leydig Cell Density and Metastatic Potential of Prostatic Adenocarcinoma
Published 1999-01-01“…Conclusions: Patients with metastatic adenocarcinoma of prostate, as a group, have a significantly lower Leydig cell density than patients without metastasis or patients without PC in compatible age groups. The hormonal relationship between this observation is however unknown. …”
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2614
Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly
Published 2024-12-01“…All patients underwent standard medical examinations, including hormonal blood tests, electrocardiograms, echocardiography, Holter monitoring electrocardiograms and magnetic resonance imaging (MRI) of the heart with gadolinium contrast, additionally 48 patients underwent T1-mapping, which is an MRI method that allows the detection of diffuse changes by measuring the values of myocardial relaxation time – T1. …”
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2615
The Effect of Contraceptive Pills on the Severity of Visceral Leishmaniasis by Measuring Some Physiological Parameters
Published 2024-12-01“…Objective: This study aims to know the effect of contraceptive pills (OC) on the severity of infection of Leishmania donovani in infected mice, by measuring the levels of the hormones estrogen and progesterone, cholesterol, and total protein in the sera of infected mice. …”
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2616
CRISPR/Cas9-editing of PRNP in Alpine goats
Published 2025-01-01“…A total of 122 two-cell-stage embryos were transferred to 46 hormonally synchronized recipient goats. Six of the goats remained pregnant and naturally gave birth to 10 offspring. …”
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2617
Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort St...
Published 2019-01-01“…Conditional logistic regression was performed to estimate the associations between hormones and outcomes. Results. After adjusting for multiple variables, the negative associations of F/E and 11-dexyocortisol with T2DM were observed in females (T3 vs. …”
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2618
Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy
Published 2025-02-01“…Examples of circadian disruptions during sepsis and septic shock include alteration or loss of hormonal rhythms controlling blood pressure and inflammation, white blood cell counts, and cytokine secretions. …”
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2619
Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity
Published 2023-01-01“…This is a cross-sectional study, in which 45 females with BMI varying from 32.8 to 51.9 kg/m2 completed a set of 4 cognitive tests (verbal paired-associate test, stroop color, digit span, and Toulouse–Pieron cancellation test) and their plasma metabolites, enzymes, and hormones related to glycemia, dyslipidemia, and liver function, as well as the biomarkers of iron status, were concomitantly analyzed. …”
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2620
First note of QTL mapping of low vigor traits using the updated F2 ‘Koroneiki’ linkage map of olive
Published 2025-01-01“…We identified two candidate genes — Acid Phosphatase 1, Shikimate O-hydroxycinnamoyltransferase, and a SNP Marker likely associated with Calcium Responsive Proteins — each potentially interacting with plant hormones to influence growth. Controlling olive tree size presents several challenges, including the genetic complexity of polygenic traits like size and vigor, and limited rootstock options. …”
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