Neurotoxic Effect of Myricitrin in Copper-Induced Oxidative Stress Is Mediated by Increased Intracellular Ca²⁺ Levels and ROS/p53/p38 Axis by Ignacija Vlašić, Antonio Krstačić-Galić, Anđela Horvat, Nada Oršolić, Anja Sadžak, Lucija Mandić, Suzana Šegota, Maja Jazvinšćak Jembrek

“…Although commonly appreciated for their anti-oxidative and neuroprotective properties, flavonoids can also exhibit pro-oxidative activity, potentially reducing cell survival, particularly in the presence of metal ions. Disrupted copper homeostasis is a known contributor to neuronal dysfunction through oxidative stress induction. …”
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Human Chorionic Plate-Derived Mesenchymal Stem Cells Restore Hepatic Lipid Metabolism in a Rat Model of Bile Duct Ligation by Yun Bin Lee, Jong Ho Choi, Eun Nam Kim, Jin Seok, Hyun-Jung Lee, Jung-Hwan Yoon, Gi Jin Kim

“…In cholestatic liver diseases, impaired bile excretion disrupts lipid homeostasis. We investigated changes of lipid metabolism, including mitochondrial β-oxidation, in a rat model of bile duct ligation (BDL) in which chorionic plate-derived mesenchymal stem cells (CP-MSCs) were transplanted. …”
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Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin by Stefano Radellini, Valentina Guarnotta, Vincenzo Sciabica, Giuseppe Pizzolanti, Carla Giordano

“…In both groups of subjects, anthropometric indices, lipid profile, glucose metabolic parameters, HbA1c, the homeostasis model assessment estimate of HOMA-insulin resistance (IR), and the insulin sensitivity index (ISI) were evaluated. …”
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Intraoperative evaluation of the intestinal wall viability by Nikita A. Adamenkov, Andrian V. Mamoshin, Viktor V. Dremin, Elena V. Potapova, Valery V. Shupletsov, Yuri V. Ivanov, Dmitry N. Panchenkov, Andrey V. Dunaev

“…Special attention is paid to the occlusion-related pathogenetic mechanism of developing mesenteric ischemia, which is accompanied by rapid development of irreversible morphological changes in the tissues and by significant disorders in the homeostasis systems of the organism. The generally available method for visual evaluation of the intestine viability is not always valid in terms of determining the degree of intensity of the ischemic changes in the intestinal wall. …”
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Effects of Acute Endurance Exercise on Plasma Protein Profiles of Endurance-Trained and Untrained Individuals over Time by Marius Schild, Gerrit Eichner, Thomas Beiter, Martina Zügel, Ilke Krumholz-Wagner, Jens Hudemann, Christian Pilat, Karsten Krüger, Andreas M. Niess, Jürgen M. Steinacker, Frank C. Mooren

“…Acute physical exercise and repeated exercise stimuli affect whole-body metabolic and immunologic homeostasis. The aim of this study was to determine plasma protein profiles of trained (EET, n=19) and untrained (SED, n=17) individuals at rest and in response to an acute bout of endurance exercise. …”
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Glymphatic system: a self-purification circulation in brain by Siying Chen, Siying Chen, Huijing Wang, Lini Zhang, Yingying Xi, Yiying Lu, Kailin Yu, Yujie Zhu, Izmailova Regina, Yong Bi, Fang Tong, Fang Tong

“…The glymphatic system theory introduces a new perspective on fluid flow and homeostasis in the brain. Here, cerebrospinal fluid and interstitial fluid (CSF-ISF) moves from the perivascular spaces (PVS) of arteries to those of veins for drainage. …”
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Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers by Caio Ambrosio Leal-Dutra, Lok Man Yuen, Bruno Augusto Maciel Guedes, Marta Contreras-Serrano, Pedro Elias Marques, Jonathan Zvi Shik

“…While autophagy is a ubiquitous and often highly derived process across the tree of life, our study reveals a new role for autophagy as a mechanism of functional integration between ant farmers and their fungal crop, and potentially as a signifier of higher-level homeostasis between uniquely life-time committed ectosymbionts.…”
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Angiotensin Inhibition Reduces the Risk of Subarachnoid Hemorrhage in Patients With Hypertension by Mohammad Hossein Abbasi, Colleen M. Brensinger, Emily K. Acton, Christopher G. Favilla, Jan‐Karl Burkhardt, Scott E. Kasner

“…Background Local angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, and impaired arterial wall integrity contributes to the pathogenesis of subarachnoid hemorrhage (SAH). …”
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Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice by Timothy M. Griffin, Ravi K. Komaravolu, Erika Barboza Prado Lopes, Padmaja Mehta-D’souza, Taylor Conner, Tessa Kovats, Susan Kovats, Madeline Allen, Peyton Harris, Mary Beth Humphrey, Hope D. Welhaven, Priyanka Brahmachary, Ronald K. June

“…Thus, although the onset of new daily exercise transiently induced synovium-IFP inflammation and altered tissue structure, sustained daily exercise promoted IFP homeostasis.…”
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Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

“…Idiopathic intracranial hypertension (IIH), a disorder of unclear pathophysiology characterised by increased cerebrospinal fluid (CSF) pressure, has been described in children with hypercortisolism, adrenal insufficiency, and hyperaldosteronism, reflecting the potential underlying involvement of the adrenal-brain axis in the regulation of CSF pressure homeostasis. Arterial hypertension caused by paediatric adenomas or tumours of the adrenal cortex or medulla has been associated with various hypertension-related neurological manifestations. …”
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Decrease of NAD+ Inhibits the Apoptosis of OLP T Cells via Inducing Mitochondrial Fission by Zhang ZY, Wang F, Zhou G

“…NAD+ supplementation mitigated these effects, suggesting a potential therapeutic strategy for restoring T cell homeostasis in OLP.Keywords: mitochondria, nicotinamide adenine dinucleotide, T cells, oral lichen planus…”
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Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes by Yi-Ling Lin, Yu-Pei Chen, Sheng-Yao Wang, Yi-Feng Kao, Chompunut Lumsangkul, Yi-Chen Chen

“…This study was to investigate the effects of CLHs on glucose homeostasis and complications in type II diabetes. Insulin resistance was induced in liver (FL83B) and muscle (C2C12) cells using 30 and 20 ng TNF-α/mL, respectively, resulting in decreased glucose uptake and lower expressions of IRβ, p-Akt/Akt, and p-GSK3/GSK. …”
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Thyroid Dysfunction in Patients with Metabolic Syndrome: A Cross-Sectional, Epidemiological, Pan-India Study by Vaishali Deshmukh, Faraz Farishta, Milind Bhole

“…Fasting plasma glucose (FPG) and fasting plasma insulin were used for the calculation of homeostasis model assessment-estimated insulin resistance (HOMA-IR). …”
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PGC1α Activators Mitigate Diabetic Tubulopathy by Improving Mitochondrial Dynamics and Quality Control by So-Young Lee, Jun Mo Kang, Dong-Jin Kim, Seon Hwa Park, Hye Yun Jeong, Yu Ho Lee, Yang Gyun Kim, Dong Ho Yang, Sang Ho Lee

“…We also examined whether the upregulation of PGC1α attenuates diabetic tubulopathy by normalizing mitochondrial homeostasis. Methods. HKC8 cells were subjected to high-glucose conditions (30 mM D-glucose). …”
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Dynamic Variation in Hippocampal Metabolism after Acute Stress Exposure: An In Vivo Proton Magnetic Resonance Spectroscopy Study at 9.4 T by Yoon Ho Hwang, Min-Hee Lee, Chang-Soo Yun, Yong-Tae Kim, Hyeon-Man Baek, Bong Soo Han, Dong Youn Kim

“…An acute stress response is a complex process that activates the neuroendocrine and metabolic systems for homeostasis. A study on acute stress is important to understand how an organism adapts to stress for survival. …”
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Variational Approaches for Drug-Disease-Gene Links in Periodontal Inflammation by Pradeep Kumar Yadalam, Prabhu Manickam Natarajan, Musab Hamed Saeed, Carlos M. Ardila

“…Introduction and Objectives: Oral diseases, including gingivitis and periodontitis, are linked to the Wnt signaling pathway, vital for bone metabolism, cementum homeostasis, and mesenchymal stem cell differentiation. …”
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To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City by Safa Nadhum Mohammed, Walaa Esmael Jassim, Najah Ali Mohammed

“…Obesity, particularly visceral fat (fat surrounding the organs) is a major cause of insulin resistance. The homeostasis model evaluation is the gold standard method for determining whether or not a person is insulin resistant. …”
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The Batten disease gene Cln3 is required for the activation of intestinal stem cell during regeneration via JAK/STAT signaling in Drosophila by Zihua Yu, Zihua Yu, Jinhua Yan, Zhiming Liu, Haiyan Wang, Guanzheng Luo, Haiyang Chen

“…Here, using Drosophila midgut system, we demonstrate that Drosophila Cln3 has no effect on midgut homeostasis maintaince, including cellular component, intestinal stem cells (ISCs) proliferation and differentiation, but is necessary for ISC activation upon tissue damage. …”
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Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children: The BCAMS Study by Lu Xu, Ming Li, Jinhua Yin, Hong Cheng, Miao Yu, Xiaoyuan Zhao, Xinhua Xiao, Jie Mi

“…IR was calculated using homeostasis model assessment (HOMA-IR). We revealed that body mass index (BMI) and waist circumference increased gradually during puberty in both genders, while fat-mass percentage (FAT%) increased steadily only in girls. …”
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Comparación entre hidratación con leche chocolatada descremada y bebida deportiva posterior al ejercicio físico en militares by Rodrigo Fernández Pávez, Francisco Fernández Frías, Carlos Jorquera Aguilera

“…Debido a esto, la reposición de líquidos y electrolitos posterior al ejercicio físico se transforma en la prioridad para restablecer la homeostasis corporal alterada durante el ejercicio físico. …”
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