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N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis
Published 2025-01-01“…Additionally, the model exhibited deregulated iron (Fe) homeostasis during lifespan. N88S seipin-expressing cells showed impaired ability to cope with iron deficiency. …”
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Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity.
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Yield, plasticity, stability and homeostasis of spring barley cultivars in the Non-Black Earth Region
Published 2022-04-01“…The highest levels of stability and homeostasis were recorded for cvs. ‘Rafael’ and ‘Lyuboyar’.Conclusion. …”
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Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Published 2025-02-01“…Here, we developed inducible whole-body Acly-knockout mice to determine the requirement for ACLY in normal tissue functions, uncovering its crucial role in skin homeostasis. ACLY-deficient skin upregulates the acetyl-CoA synthetase ACSS2; deletion of both Acly and Acss2 from the skin exacerbates skin abnormalities, with differential effects on two major lipid-producing skin compartments. …”
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The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis.
Published 2025-01-01“…Deletion of the conserved C-terminus of Inc does not alter Cul3 binding but abolishes Inc activity in the context of sleep and synaptic homeostasis, indicating that the Inc C-terminus has the properties of a substrate recruitment domain. …”
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86
A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration
Published 2025-01-01“…Abstract Balanced self-renewal and differentiation of stem cells are crucial for maintaining tissue homeostasis, but the underlying mechanisms of this process remain poorly understood. …”
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87
Regulation of calcium homeostasis in endoplasmic reticulum–mitochondria crosstalk: implications for skeletal muscle atrophy
Published 2025-01-01“…A pivotal aspect of calcium homeostasis involves the dynamic interaction between mitochondria and the ER. …”
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88
Association of Phthalate Exposure with Thyroid Function and Thyroid Homeostasis Parameters in Type 2 Diabetes
Published 2021-01-01“…Urinary phthalate metabolites may be associated with thyroid function and thyroid homeostasis parameters among participants with type 2 diabetes. …”
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Water homeostasis gene expression in the kidney of broilers divergently selected for water conversion ratio
Published 2025-01-01“…Two 2 × 2 factorial experiments were conducted to assess the gene expression profile of systems involved in renal water homeostasis. In Exp. 1, male and female HWE and LWE broilers were individually phenotyped between 4 and 6 wks of age to determine growth performance and water conversion ratio (g water intake/g body weight gain). …”
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Autophagy protein Atg7 is essential for maintaining malaria parasite cellular homeostasis and organelle biogenesis
Published 2025-02-01“…Overall, this study establishes the essential functions of Atg7 in Plasmodium blood and liver stages, and highlights its role in maintaining the parasite’s cellular homeostasis and organelle biogenesis.IMPORTANCEThe malaria life cycle involves two hosts, mosquitoes and vertebrates. …”
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93
SAMHD1 shapes deoxynucleotide triphosphate homeostasis by interconnecting the depletion and biosynthesis of different dNTPs
Published 2025-01-01“…We show how this allosteric regulation shapes deoxynucleotide homeostasis by balancing dNTP production and SAMHD1-catalyzed depletion. …”
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Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis
Published 2025-01-01Subjects: Get full text
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The Serum Level of Fibroblast Growth Factor-23 and Calcium-Phosphate Homeostasis in Obese Perimenopausal Women
Published 2011-01-01“…Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. …”
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Exosomal non-coding RNAs in the regulation of bone metabolism homeostasis: Molecular mechanism and therapeutic potential
Published 2025-01-01“…In this review, we focus on the regulation mechanism and function of bone homeostasis mediated by exosomal ncRNAs (Exos-ncRNAs), including macrophage polarization, autophagy, angiogenesis, signal transduction and competing endogenous RNA (ceRNA). …”
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Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn’s Disease
Published 2025-02-01“…Determination of thiol/disulfide homeostasis could help differentiate between the active and remission phases of the disease. …”
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Undernutrition disrupts jejunal and ileal microbiota and epithelial tissue homeostasis in a pregnant sheep model
Published 2025-03-01“…This study aimed to unravel how undernutrition reshapes the microbial composition and the homeostasis of epithelium in the jejunum and ileum. …”
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