Unraveling Ferroptosis: A New Frontier in Combating Renal Fibrosis and CKD Progression by Rui Jin, Yue Dai, Zheng Wang, Qinyang Hu, Cuntai Zhang, Hongyu Gao, Qi Yan

“…Kidney fibrosis is a common outcome of CKD progression, with abnormal fatty acid oxidation (FAO) disrupting renal energy homeostasis and leading to functional impairments. This results in maladaptive repair mechanisms and the secretion of profibrotic factors, and exacerbates renal fibrosis. …”
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Gene expression signatures between Limia perugiae (Poeciliidae) populations from freshwater and hypersaline habitats, with comparisons to other teleosts. by Elizabeth J Wilson, Nick Barts, John L Coffin, James B Johnson, Carlos M Rodríguez Peña, Joanna L Kelley, Michael Tobler, Ryan Greenway

“…Our analyses of gill gene expression revealed potential molecular mechanisms underlying salinity tolerance in this species, including the enrichment of genes involved in ion transport, maintenance of chemical homeostasis, and cell signaling in the hypersaline population. …”
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The Light and Shadow of Senescence and Inflammation in Cardiovascular Pathology and Regenerative Medicine by Laura Iop, Eleonora Dal Sasso, Leonardo Schirone, Maurizio Forte, Mariangela Peruzzi, Elena Cavarretta, Silvia Palmerio, Gino Gerosa, Sebastiano Sciarretta, Giacomo Frati

“…At the molecular level, in fact, a gradual weakening of the cellular processes regulating cardiovascular homeostasis occurs in aging cells. Atherosclerosis and heart failure are particularly correlated with aging-related cardiovascular senescence, that is, the inability of cells to progress in the mitotic program until completion of cytokinesis. …”
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Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway by Oluwatoyin O. Ojo, Deborah I. Fatokun, Ikechukwu P. Ejidike, Rachel U. Awolope, Saheed O. Sanni

“…Bioflavonoids are known to influence redox homeostasis in cells; the study therefore investigates the efficacy of quercetin and its zinc and iron metal complexes on sodium arsenite (NaAr)-intoxication in rats. …”
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ENL mutation and AML: a new model that reveals oncogenic condensate's function in leukemogenesis by Zhong Fan, Yanan Jiang, Xiaotian Zhang

“…Precise regulation of gene expression is essential for proper development and the maintenance of homeostasis in organisms. Studies have shown that some transcriptional regulatory proteins influence gene expression through the formation of dynamic, locally concentrated assemblies known as condensates, while dysregulation of transcriptional condensates was associated with several cancers, such as Ewing sarcoma and AML [Wang Y et al. (2023) Nat Chem Biol 19, 1223–1234; Chandra B et al. (2022) Cancer Discov 12, 1152–1169]. …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…In optimal conditions, autophagy in plants ensures cellular homeostasis, proper plant growth, and fitness. Moreover, autophagy is essential during stress responses in plants and aids in survival of plants. …”
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The effect of blood transfusion on serum hepcidin levels in chronically transfused patients of β-thalassemia major: An observational study in a tertiary care centre in Western Maha... by Sujay Bhowmik, Amit Kumar Biswas, Ajay Kumar Baranwal, Amit Ajay Pawar, Ujjwal Dimri

“…INTRODUCTION: Hepcidin is the key regulator of systemic iron homeostasis. In iron-loading anemias, hepcidin levels are regulated by opposite forces of erythropoiesis and iron overload. …”
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A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis by Chiara Spinsante, Federica Carducci, Elisa Carotti, Adriana Canapa, Davide Bizzaro, Maria Assunta Biscotti, Marco Barucca

“…Most of these are involved in the transduction of key signals during embryonic development and in the regulation of cholesterol homeostasis. In oviparous animals, the VLDL receptor is also known as VTGR since it facilitates the uptake of vitellogenin in ovary. …”
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Vitamin A and its influence on tumour extracellular matrix by Guoqing Xie, Shun Cao, Guangchun Wang, Xianzhong Zhang, Yu Zhang, Haofan Wu, Shuxian Shen, Jiandong Le, Keqiang Li, Zhenlin Huang

“…Its derivatives influence cell differentiation, proliferation, and tissue homeostasis, making them significant in cancer research due to their effects on both normal and tumour cells. …”
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(+)-Z-Bisdehydrodoisynolic Acid Enhances Basal Metabolism and Fatty Acid Oxidation in Female Obese Zucker Rats by William J. Banz, April D. Strader, Kolapo M. Ajuwon, Yuqing Hou, Cal Y. Meyers, Jeremy E. Davis

“…Similar to our previous findings, (+)-Z-BDDA reduced weight gain and improved lipid and glucose homeostasis in OZR rats. Furthermore, resting energy expenditure was increased by (+)-Z-BDDA, as evident by heat production and oxygen consumption. …”
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Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study by Yuliya Boyko, René Holst, Poul Jennum, Helle Oerding, Miki Nikolic, Palle Toft

“…Critically ill patients have abnormal circadian and sleep homeostasis. This may be associated with higher morbidity and mortality. …”
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The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases by Lingyi Yang, Shuli Chen, Qiuyu Zhao, Ying Sun, Hong Nie

“…Furthermore, emerging data show that Bach2 regulates transcriptional activity in T cells at super enhancers or regions of high transcriptional activity, thus stabilizing immunoregulatory capacity and maintaining T cell homeostasis. Bach2 is also critical for the formation and function of CD4+ T cell lineages (Th1, Th2, Th9, Th17, T follicular helper (Tfh), and regulatory T (Treg) cells). …”
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The Effect of P-Cymene on Glucose, Insulin, Antioxidant Power, and the Level of AKT Gene mRNA in Streptozotocin-Induced Diabetes Model in Male Wistar Rats by Maryam Arabloei Sani, Zahra Hajebrahimi, Parichehreh Yaghmaei, Nasim Hayati Roodbari

“…The AKT signaling pathways plays a critical role in regulating glucose homeostasis and proliferation of β cells. P-cymene is an aromatic monotropene with antioxidant and anti-inflammatory properties. …”
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Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases by Zhiping Wei, Jintao Yuan, Gaoying Wang, Dickson Kofi Wiredu Ocansey, Zhiwei Xu, Fei Mao

“…MSCs can regulate T cell subsets to restore their immune homeostasis toward disease resolution in autoimmune conditions. …”
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Enhancing proteasome activity by NMDAR antagonists explains their therapeutic effect in neurodegenerative and mental diseases by Fikret Sahin, Aslihan Gunel, Buse Turegun Atasoy, Ulku Guler, Bekir Salih, Isinsu Kuzu, Mehmet Taspinar, Ozgur Cinar, Selda Kahveci

“…Via the ubiquitin-independent 20S proteasome pathway (UIPS), these drugs maintain cellular protein homeostasis, which is crucial as proteasome activity declines with age, leading to protein aggregation and disease symptoms. …”
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Iron and ferroptosis in kidney disease: molecular and metabolic mechanisms by Wenjie Wang, Jingdi Chen, Liying Zhan, Handong Zou, Lu Wang, Mengmeng Guo, Hang Gao, Jing Xu, Wei Wu

“…Maintaining iron homeostasis is necessary for kidney functioning. There is more and more research indicating that kidney disease is often caused by iron imbalance. …”
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Regulator of Calcineurin 1 in Periodontal Disease by Ulrike Peters, Eleni Solominidou, Yüksel Korkmaz, Stefan Rüttermann, Astrid Klocke, Thomas Frank Flemmig, Thomas Beikler

“…During an acute infection, however, rcan1 seems to be upregulated in endothelial cells, indicating a modulating role in immune homeostasis of periodontal tissues.…”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia by Anna Picca, Francesca Fanelli, Riccardo Calvani, Giuseppina Mulè, Vito Pesce, Alex Sisto, Cecilia Pantanelli, Roberto Bernabei, Francesco Landi, Emanuele Marzetti

“…Advanced age is characterized by several changes, one of which is the impairment of the homeostasis of intestinal microbiota. These alterations critically influence host health and have been associated with morbidity and mortality in older adults. …”
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Associations of Plasma BDNF and BDNF Gene Polymorphism with Cardiometabolic Parameters in Thai Children: A Pilot Study by Kanjana Suriyaprom, Banchamaphon Pheungruang, Somchai Pooudong, Pumpath Putpadungwipon, Chutima Sirikulchayanonta

“…The brain-derived neurotrophic factor (BDNF) has been demonstrated to play a role in controlling energy homeostasis and cardiovascular regulation. Objectives. …”
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Combined Treatment with Zinc Aspartate and Intravenous Immunoglobulins (IVIGs) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) by Diana Straubel, Anja Thielitz, Annegret Reinhold, Kurt Grüngreiff, Dirk Reinhold

“…The trace element zinc is shown to play a regulatory role in the maintenance of immune functions. Changes of zinc homeostasis affect both the innate and the adaptive immune system. …”
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