Effects of ginseng dietary supplementation on a high-Fat diet-induced obesity in C57BL/6 Mice by Jia-Ni Lin, Pei-Sheng Lee, Nai-Wen Mei, An-Chin Cheng, Roch-Chui Yu, Min-Hsiung Pan

“…Excess caloric intake increases the amount of adipose tissue and contributes to metabolic disorders in disrupted metabolic homeostasis. This study aimed to investigate the anti-obesity effects of ginseng and the alternation of gut microbiota composition in high-fat diet (HFD)-induced obesity. …”
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Evaluation of serum leptin and adiponectin and their associations with obesity-related renal injury among Egyptian adolescents by Azza A El-Shaheed, Reham F. Fahmy, Nermine N. Mahfouz, Salwa R El-Zayat, Hiba Sibaii, Rehab S.I. Moustafa

“…Serum fasting glucose and insulin were analyzed, and a homeostasis model assessment of insulin resistance was calculated. …”
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Dietary Intake of Chromista Oil Alters Hepatic Metabolomic Profile of Mice With Excess Fat Mass by Bret M Rust, Forrest H Nielsen, Lin Yan

“…Findings from this study indicate that dietary intake of chromista oil does not improve glucose homeostasis or alter the diminished metabolic flexibility in mice with excess adiposity induced by the HFD. …”
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A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects by Joseph Schwager, Nathalie Richard, Rotraut Schoop, Swen Wolfram

“…Thus, RHP contributed to restore cellular homeostasis in PBL and chondrocytes. RH preparations from fruits without seeds are thus expected to have an improved OA-preventive or OA-therapeutic profile, as subsequently shown in a related clinical trial.…”
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Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease by Jie Pan, Jie Zhong, Ji Geng, Jane Oberhauser, Shihua Shi, Jun Wan

“…However, microglia, the primary immune cells of the central nervous system, are known to maintain homeostasis through the phagocytic clearance of protein aggregates and cellular debris. …”
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Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model by Hung-Chih Chen, Yu-Che Cheng, Marvin L. Hsieh, Po-Ju Lin, Emily F. Wissel, Theodore Steward, Cindy M. C. Chang, Jennifer Coonen, Timothy A. Hacker, Timothy J. Kamp, Patrick C. H. Hsieh

“…The interplay between shift in microbial community and host homeostasis during treatment suggests gut microbiome modulation could improve cell therapy outcomes.…”
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Fetal Programming of Body Composition, Obesity, and Metabolic Function: The Role of Intrauterine Stress and Stress Biology by Sonja Entringer, Claudia Buss, James M. Swanson, Dan M. Cooper, Deborah A. Wing, Feizal Waffarn, Pathik D. Wadhwa

“…We suggest that intrauterine stress exposure may interact with the nutritional milieu, and that stress biology may represent an underlying mechanism mediating the effects of diverse intrauterine perturbations, including but not limited to maternal nutritional insults (undernutrition and overnutrition), on brain and peripheral targets of programming of body composition, energy balance homeostasis, and metabolic function. We discuss putative maternal-placental-fetal endocrine and immune/inflammatory candidate mechanisms that may underlie the long-term effects of intrauterine stress. …”
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Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis by Hoyeon Lee, Sang Woo Cho, Hyo Sun Cha, Kun Tae, Cheol Yong Choi

“…Abstract Background The Hippo signaling pathway involves a kinase cascade that controls phosphorylation of the effector proteins YAP and TAZ, leading to regulation of cell growth, tissue homeostasis, and apoptosis. Morusin, a compound extracted from Morus alba, has shown potential in cancer therapy by targeting multiple signaling pathways, including the PI3K/Akt/mTOR, JAK/STAT, MAPK/ERK, and apoptosis pathways. …”
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Adipocyte-Specific Fatty Acid-Binding Protein (AFABP) and Chemerin in Association with Gestational Diabetes: A Case-Control Study by Maryam Mosavat, Mitra Mirsanjari, Bashir A. Lwaleed, Maherah Kamarudin, Siti Zawiah Omar

“…Adipocytokines participate in regulating the inflammatory response in glucose homeostasis and type 2 diabetes. However, among these peptides, the role of adipocyte-specific fatty-acid-binding protein (AFABP), chemerin, and secreted protein acidic and rich in cysteine (SPARC) in gestational diabetes (GDM) has not been fully investigated. …”
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Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target by Hui-Yuan Li, Li-Feng Huang, Xiao-Rong Huang, Dan Wu, Xiao-Cui Chen, Ji-Xin Tang, Ning An, Hua-Feng Liu, Chen Yang

“…The molecular chaperones, autophagy, and proteasome degradation pathways inhibit ERS and restore ER homeostasis to improve the dysfunction of immune cells and renal resident cell injury. …”
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ASSOCIATION BETWEEN CHRONIC APICAL PERIODONTITIS AND OXIDATIVE STRESS OR META-INFLAMMATION: A CROSS-SECTIONAL OBSERVATIONAL STUDY by Antonia Boca, Ada Delean, Sanda Ileana Cîmpean, Adina Bianca Boșca, Cosmina Ioana Bondor, Sebastian Candrea, SALIVAGES Project group, Aranka Ilea

“…However, its cumulative effect with other associated pathologies could impact the overall modulation of the inflammatory response and general homeostasis. Further research is needed to confirm these findings.…”
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A Label-Free Colorimetric Aptasensor for Flavokavain B Detection by Sisi Ke, Ningrui Wang, Xingyu Chen, Jiangwei Tian, Jiwei Li, Boyang Yu

“…Flavokavain B (FKB), a hepatotoxic chalcone from <i>Piper methysticum</i> (kava), has raised safety concerns due to its role in disrupting redox homeostasis and inducing apoptosis in hepatocytes. Conventional chromatographic methods for FKB detection, while sensitive, are costly and impractical for field applications. …”
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Metallothioneins in Inflammatory Bowel Diseases: Importance in Pathogenesis and Potential Therapy Target by Anna Socha-Banasiak, Patrycja Sputa-Grzegrzółka, Jędrzej Grzegrzółka, Krzysztof Pacześ, Piotr Dzięgiel, Beata Sordyl, Hanna Romanowicz, Elżbieta Czkwianianc

“…Metallothioneins (MTs) belong to the group of low molecular weight proteins, which, among others, regulate the inflammation and homeostasis of heavy metals as well as participating in the regulation of the intensity of oxidative stress. …”
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IP3 Receptors, Mitochondria, and Ca2+ Signaling: Implications for Aging by Jean-Paul Decuypere, Giovanni Monaco, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Geert Bultynck

“…Proteins that prevent or promote apoptosis and autophagy can affect intracellular Ca2+ dynamics and homeostasis through binding and modulation of the intracellular Ca2+-release and Ca2+-uptake mechanisms. …”
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Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis by Georg Auburger, Suzana Gispert, Nadine Brehm

“…Thus, we report selective novel endogenous stress responses in brain, which highlight early dysregulations of mitochondrial homeostasis and midbrain vulnerability.…”
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Selective mPGES-1 Inhibitor Ameliorated Adjuvant-Induced Arthritis in the Rat Model by Min Ji Kim, Hwi-Ho Lee, Choi Kim, Ja Yeon Lee, Kyung-Sook Chung, Kyung-Tae Lee, Jae Yeol Lee

“…Endogenous prostaglandin E2 (PGE2) plays an important role in maintaining the homeostasis conditions. However, the overexpression of PGE2 in response to various inflammatory stimulations is an important target of anti-inflammatory drugs. …”
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lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases by Lulingxiao Nie, Peng Zhang, Qian Wang, Xinyi Zhou, Qi Wang

“…Autophagy defects, oxidative stresses, senescence-associated secretory phenotypes (SASPs), and DNA damage generally contribute to inflammaging and are largely regulated by numerous lncRNA through two-level vicious cycles disrupting cellular homeostasis: (1) inflammaging and the cellular senescence cascade and (2) autophagy defects, oxidative stress, and the SASP cascade. …”
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GC-MS Analysis of phytochemical compounds from Javan olive leaves (Olea javanica) extract and bioactivity screening of antidiabetes through in silico approach by Lailatus Fitri, Ayu Dewi Wulandari, Tri Sumaryono, Nur Fatimah Azzahra Haibaturrahma, Bunga Nanda Agustina, Muhammad Badrut Tamam

“…The Glucokinase (HGKA) enzyme, which is mainly found in the liver and pancreatic beta cells, is involved in maintaining blood glucose homeostasis. Therefore, the purpose of this study on GC-MS and in silico analysis was designed to determine the interaction between Glucokinase and the compound (ligand) of Java olive leaf extract (Olea javanica). …”
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Capsaicin alleviates the hepatic clock gene disruption and gut microbiota dysbiosis in circadian rhythm disorder mouse model by Bolin Lin, Chi-Tang Ho, Yawen Wang, Jie Xiao, Muwen Lu

“…In this work, a circadian disorder mouse model induced by constant darkness (CD) was constructed to investigate the regulating effects of capsaicin (CAP) on disturbances of metabolism homeostasis and gut microbiota in the respect of circadian rhythm-related mechanisms. …”
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Occurring of In Vitro Functional Vasculogenic Pericytes from Human Circulating Early Endothelial Precursor Cell Culture by Silvia Cantoni, Francesca Bianchi, Margherita Galletti, Elena Olivi, Francesco Alviano, Nazzareno Galiè, Carlo Ventura

“…Pericytes are periendothelial cells of the microcirculation which contribute to tissue homeostasis and hemostasis by regulating microvascular morphogenesis and stability. …”
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