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821
Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies
Published 2015-01-01“…Those products can successfully modulate parasite-specific immune responses as well as responses to unrelated antigens (either self or nonself in origin), providing an anti-inflammatory milieu and maintaining homeostasis. It is clear, based on the findings from animal model studies, that T. spiralis and its products induce an immunomodulatory network (which encompasses Th2- and Treg-type responses) that may allow the host to deal with various hyperimmune-associated disorders as well as tumor growth, although the latter still remains unclear. …”
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822
PIWI proteins and piRNAs: key regulators of stem cell biology
Published 2025-02-01“…Similarly, in Drosophila intestinal stem cells, the PIWI protein Piwi regulates metabolic pathways and genome integrity, impacting longevity and gut homeostasis. In this case, piRNAs appear absent in the gut, suggesting piRNA-independent regulatory mechanisms. …”
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823
Development and Validation of Cloud-based Heart Rate Variability Monitor
Published 2024-12-01“…Aims: Medical investigations carried out at dispensaries or hospitals impose substantial physiological and psychological stress (white coat effect), disrupting cardiovascular homeostasis, which can be taken care by point-of-care cloud computing system to facilitate secure patient monitoring. …”
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824
Relationship of asprosin and diabetes: a meta-analysis
Published 2025-01-01“…Previous research suggests that asprosin may contribute to the development of diabetes by regulating glucose homeostasis, appetite, insulin secretion, and insulin sensitivity. …”
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825
Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies
Published 2025-12-01“…Systemically, liver disease, liver function failure, portosystemic shunting, and associated multi-organ dysfunction result in the increase of disease-causing neurotoxins in the circulation, which impairs cerebral homeostasis. Key circulating neurotoxins are ammonia and inflammatory mediators. …”
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826
Understanding the complex function of gut microbiota: its impact on the pathogenesis of obesity and beyond: a comprehensive review
Published 2024-12-01“…Furthermore, the review underscores the integration of microbial metabolites with pharmacological agents such as orlistat and semaglutide in restoring microbial homeostasis. However, more clinical tests are essential to refine the doses, frequency, and lasting effectiveness of these treatments. …”
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827
Follistatin Alleviates Synovitis and Articular Cartilage Degeneration Induced by Carrageenan
Published 2014-01-01“…These data indicate that activin-follistatin signaling is involved in joint inflammation and cartilage homeostasis. Our data suggest that follistatin can be a new therapeutic target for inflammation-induced articular cartilage degeneration.…”
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828
New biomarkers for diagnosis of polycystic ovary syndrome
Published 2023-04-01“…Mean value of serum insulin and homeostasis model assessment-estimated insulin resistance (HOMA-IR) had been greater between cases group than the control. …”
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829
Electromagnetic Fields for the Regulation of Neural Stem Cells
Published 2017-01-01“…Neural stem cells (NSCs) in adult human brain are able to self-renew and possess multidifferential ability to maintain homeostasis and repair damage after acute central nervous system. …”
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830
The impact of tuberculosis-induced hyperglycemia on pulmonary microbiota and airway mucus secretion in individuals not previously diabetic: A systematic review and meta-analysis pr...
Published 2025-01-01“…The high glucose concentration is proposed to alter the composition of the lung microbiota and airway homeostasis, exerting an influence on TB disease and treatment outcomes. …”
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831
Mitochondria of transformed cell as a target of antitumor influence
Published 2020-06-01“…Mitochondria are intracellular organelles in eukaryotic cells that participate in bioenergy metabolism and cell homeostasis, including ATP generation through electron transport and oxidative phosphorylation in combination with oxidation of metabolites by the tricarboxylic acid cycle and fatty acid catabolism via β-oxidation. the production of reactive oxygen species, as well as the initiation and implementation of apoptosis. …”
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832
Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism
Published 2010-01-01“…To maintain homeostasis under diverse metabolic conditions, it is necessary to coordinate nutrient-sensing pathways with the immune response. …”
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833
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834
Macrophages in Tumor Microenvironments and the Progression of Tumors
Published 2012-01-01“…Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. Macrophages can be activated by a variety of stimuli and polarized to functionally different phenotypes. …”
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835
Toll-like receptor 2/6-stimulated HMC-1 mast cells promote keratinocyte migration in wound healing.
Published 2025-01-01“…Our findings indicated that TLR2/6-stimulated mast cells contributed to skin homeostasis by promoting tryptase-dependent wound healing.…”
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836
Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage
Published 2018-01-01“…They fulfill a variety of roles in immune regulation, wound healing, and tissue homeostasis preservation. Macrophages are characterized by high heterogeneity, which can polarize into at least two major extremes, M1-type macrophages (classical activation) which are normally derived from monocytes and M2-type macrophages (alternative activation) which are mostly those tissue-resident macrophages. …”
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837
High-resolution mapping of cell cycle dynamics during steady-state T cell development and regeneration in vivo
Published 2025-01-01“…Taken together, our results highlight intrathymic cell cycle regulation as an adjustable system to maintain physiologic tissue homeostasis and foster our understanding of dysregulation of the T cell developmental program.…”
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838
Vaccination with an Attenuated Ferritin Mutant Protects Mice against Virulent Mycobacterium tuberculosis
Published 2015-01-01“…We previously showed that a ferritin (bfrB) mutant of M. tuberculosis has altered iron homeostasis and increased sensitivity to antibiotics and to microbicidal effectors produced by activated macrophages. …”
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839
COVID-19 PANDEMIC: STRENGTHENING THE IMMUNITY BY REENGINEERING AMONG MENTAL HEALTH TANGLES
Published 2023-03-01“…To achieve good mental health and a strong immunity system, maintaining the homeostasis of mind and body, engagement in close connections, and social support, using low-stressor techniques, nearness to the environment, practicing Yoga and meditation, infusing positivity, and following healthy lifestyles are necessary for people. …”
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840
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses
Published 2018-01-01“…However, we observed autophagic flux during differentiation as a protective mechanism that allows cells to maintain homeostasis and remove dysfunctional mitochondria.…”
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