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701
Protocol for isolation of human bone marrow stromal cells and characterization of cellular metabolism
Published 2025-03-01“…Summary: Bone marrow stromal cells (BMSCs) serve as a valuable reservoir of multipotent stem cells important in the regulation of bone homeostasis and energy metabolism. Here, we present a protocol for isolating human BMSCs (hBMSCs) and characterizing their cellular metabolism related to hBMSC functional properties. …”
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702
Pexophagy: The Selective Degradation of Peroxisomes
Published 2012-01-01“…The exigency of all eukaryotic cells to quickly adapt to different environmental factors requires the ability to precisely and efficiently control peroxisome number and functionality. Peroxisome homeostasis is achieved by the counterbalance between organelle biogenesis and degradation. …”
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703
Modelling Peroxisomal Disorders in Zebrafish
Published 2025-01-01“…Peroxisomes are ubiquitous, dynamic, oxidative organelles with key functions in cellular lipid metabolism and redox homeostasis. They have been linked to healthy ageing, neurodegeneration, cancer, the combat of pathogens and viruses, and infection and immune responses. …”
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704
Correspondence: insulin resistance and chronic kidney disease in patients without diabetes
Published 2025-02-01“…Known causes of CKD and relevant covariates should be identified where possible. Homeostasis model assessment of insulin resistance (HOMA-IR), being an indirect measure of insulin resistance, has limited sensitivity and specificity compared to direct methods like the hyperinsulinaemic-euglycaemic clamp. …”
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705
The Effectiveness Of Spiritual Emotional Freedom Technique (SEFT) On The Decrease of Psychological Issues In Cancer Patients: A Systematic Review
Published 2024-12-01“…Cancer is a cellular disease characterised by disruption or failure of multi-application regulatory mechanisms and other homeostasis functions in multicellular organisms. Basically, cancer can occur due to genetic changes (mutations), especially in the gene that regulates growth, namely oncogenes. …”
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706
A Mechanistic Insight into the Pathogenic Role of Interleukin 17A in Systemic Autoimmune Diseases
Published 2022-01-01“…Amongst other mechanisms that prevent tissue injury mediated by potential microbial threats and promote restoration of epithelial homeostasis, IL-17A attracts effector cells to the site of inflammation and support the host response by driving the development of ectopic lymphoid structures. …”
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707
The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Published 2022-01-01“…Epigenetics describes changes in gene expression rather than changes in DNA and broadly happens in bone homeostasis, embryogenesis, stem cell fate, and disease development. …”
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708
Mesenchymal Stem Cells Ameliorate Hyperglycemia in Type I Diabetic Developing Male Rats
Published 2022-01-01“…These results indicate that MSC therapy of STZ-induced diabetic developing rats during an early stage has the capacity of β cell restoration and the control of blood glycemic homeostasis.…”
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709
Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
Published 2010-01-01“…The UPR is tailored essentially to reestablish ER homeostasis also through adaptive mechanisms involving the stimulation of autophagy. …”
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710
Panoptosis – new frontier in research in head neck cancer
Published 2024-06-01“…The innate immune system provides the first line of defense against cellular perturbations, and inflammatory programmed cell death is elicited in response to microbial infections or alterations in cellular homeostasis. Programmed cell death (PCD) is a key mechanism for studying anticancer drugs and has a significant impact on the development and management of cancer. …”
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711
Host-Bacteria Crosstalk at the Dentogingival Junction
Published 2012-01-01“…During periodontal disease progression, the dental bacterial plaque, junctional epithelium (JE), inflammatory cells, connective tissue, and bone all go through a series of changes. The tissue homeostasis is turned into tissue destruction and progression of periodontitis. …”
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712
PPAR Agonists and Cardiovascular Disease in Diabetes
Published 2008-01-01“…Peroxisome proliferators activated receptors (PPARs) are ligand-activated nuclear transcription factors that play important roles in lipid and glucose homeostasis. To the extent that PPAR agonists improve diabetic dyslipidaemia and insulin resistance, these agents have been considered to reduce cardiovascular risk. …”
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713
Role of Hypothalamus in Acupuncture’s Effects
Published 2025-01-01“…Among the brain regions, the hypothalamus, a small yet critical region in the brain, plays a pivotal role in maintaining homeostasis by regulating a wide array of physiological processes, including stress responses, energy balance, and pain modulation. …”
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714
The role of immunity in insulin resistance in patients with polycystic ovary syndrome
Published 2025-01-01“…Therefore, this review aims to elucidate the interplay between IR in PCOS patients, the controlled immune response orchestrated by immune cells and immunomodulatory molecules, and their interactions with adipocytes, hyperandrogenemia, chronic inflammation, and metabolic homeostasis.…”
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715
Emerging Therapeutic Strategies for Limbal Stem Cell Deficiency
Published 2018-01-01“…LESCs have been demonstrated to play an important role in maintaining corneal epithelium homeostasis. Many ocular surface diseases, including intrinsic (e.g., Sjogren’s syndrome) or extrinsic (e.g., alkali or thermal burns) insults, which impair LESCs, can lead to limbal stem cell deficiency (LSCD). …”
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716
Hypoxia-Induced Reactive Oxygen Species: Their Role in Cancer Resistance and Emerging Therapies to Overcome It
Published 2025-01-01“…Normal tissues typically maintain partial oxygen pressure within a range of 3–10% oxygen, ensuring homeostasis through a well-regulated oxygen supply and responsive vascular network. …”
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717
Iron-mediated post-transcriptional regulation in Toxoplasma gondii.
Published 2025-02-01“…Iron is required to support almost all life; however, levels must be carefully regulated to maintain homeostasis. Although the obligate parasite Toxoplasma gondii requires iron, how it responds upon iron limitation has not been investigated. …”
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718
Case report: Discovery of novel CTNNB1 mutations and comparison of clinical characteristics in two patients with NEDSDV
Published 2025-01-01“…CTNNB1, which encodes β-catenin, plays an essential role in the Wnt signaling pathway and regulates cellular homeostasis. Mutations in this gene can lead to neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV). …”
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719
Neuroinflammation and iron metabolism after intracerebral hemorrhage: a glial cell perspective
Published 2025-01-01“…Degradation of hemoglobin produces large amounts of iron ions, leading to an imbalance of iron homeostasis and the production of large quantities of harmful hydroxyl radicals. …”
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720
Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals.
Published 2013-01-01“…Hedgehog (Hh) proteins control animal development and tissue homeostasis. They activate gene expression by regulating processing, stability, and activation of Gli/Cubitus interruptus (Ci) transcription factors. …”
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