Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases by Ya-Min Ma, Lan Zhao

“…It mediates the information exchange between different cellular pathways in cellular homeostasis and stress response and regulates the differentiation, plasticity, and neurotransmission of neurons. …”
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Editorial: Community series in towards precision medicine for immune-mediated disorders: advances in using big data and artificial intelligence to understand heterogeneity in infla... by Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Xu-jie Zhou, Yasmina Laouar, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi

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Protocol for the site-specific isolation of mouse endothelial cells using the modified Häutchen technique by Alexander Brückner, Adrian Brandtner, Sarah Rieck, Bernd K. Fleischmann, Daniela Wenzel

“…Summary: Endothelial cells (ECs) play a major role in vascular homeostasis and pathology. They show a pronounced heterogeneity between different organs as well as within the same organ. …”
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Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines by Malgorzata Adamiec-Organisciok, Magdalena Wegrzyn, Lukasz Cienciala, Ngoni Magate, Magdalena Skonieczna, Joanna Nackiewicz

“…Regulated cell death is a fundamental biological process that plays a crucial role in maintaining tissue homeostasis and eliminating damaged or unnecessary cells. …”
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Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue by Sofia Dias, Sílvia Paredes, Laura Ribeiro

“…Metabolic syndrome can be defined as a state of disturbed metabolic homeostasis characterized by visceral obesity, atherogenic dyslipidemia, arterial hypertension, and insulin resistance. …”
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A Highly Selective Fluorescent Probe for Hypochlorous Acid in Living Cells Based on a Naphthalene Derivative by Jingguo Sun, Junhong Xu, Qiujuan Ma, Guojiang Mao, Nannan Zhu, Meiju Tian, Linke Li, Shuzhen Liu

“…Hypochlorous acid (HOCl) was crucial for maintaining the homeostasis in cells and plays vital roles in many physiological and pathological processes. …”
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Therapeutic Implications of PPARγ in Cardiovascular Diseases by Hiroshi Hasegawa, Hiroyuki Takano, Issei Komuro

“…Although PPARγ is expressed predominantly in adipose tissue and associated with adipocyte differentiation and glucose homeostasis, PPARγ is also present in a variety of cell types including vascular cells and cardiomyocytes. …”
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Structural insights into GrpEL1-mediated nucleotide and substrate release of human mitochondrial Hsp70 by Marc A. Morizono, Kelly L. McGuire, Natalie I. Birouty, Mark A. Herzik

“…Abstract Maintenance of protein homeostasis is necessary for cell viability and depends on a complex network of chaperones and co-chaperones, including the heat-shock protein 70 (Hsp70) system. …”
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Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation: Implications in Cancer and Neurodegeneration by Giuseppina Di Giacomo, Salvatore Rizza, Costanza Montagna, Giuseppe Filomeni

“…., cancer and neurodegeneration), conditions in which alterations of mitochondrial homeostasis and activation of cellular processes dependent on it have been reported as well. …”
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Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor by Seong-Hoon Yun, Sang-Heum Han, Joo-In Park

“…PPARγ coactivator-1α (PGC-1α), initially identified as a PPARγ-interacting protein, is an important regulator of diverse metabolic pathways, such as oxidative metabolism and energy homeostasis. The role of PGC-1α in diabetes, neurodegeneration, and cardiovascular disease is particularly well known. …”
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Hemoglobin: A Nitric-Oxide Dioxygenase by Paul R. Gardner

“…NOD knockout organisms and cells expressing recombinant NODs are helping to advance our understanding of NO actions in microbial infection, plant senescence, cancer, mitochondrial function, iron metabolism, and tissue O2 homeostasis. NOD inhibitors are being pursued for therapeutic applications as antibiotics and antitumor agents. …”
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Crosstalk between Gut Microbiota and Cancer Immunotherapy: Present Investigations and Future Perspective by Yuhui Tang, Qiaoting Cai, Zhi Tian, Wenkuan Chen, Hailin Tang

“…Gut microbiota is crucial for protecting the homeostasis of immune locally and systemically, and its dysbiosis is essentially correlated to tumorigenesis, cancer progression, and refractoriness to cancer treatments, including the novel immunotherapy. …”
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Dolor agudo posoperatorio en el anciano by Evangelina Dávila Cabo de Villa, Bárbara Lucía Leyva Cabezas

“…Entre los principales objetivos del anestesiólogo se encuentra mantener la homeostasis del organismo, no solo durante el desarrollo del acto quirúrgico, sino también en el período posoperatorio. …”
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The Regulation of ROS and Phytohormones in Balancing Crop Yield and Salt Tolerance by Lei Jiang, Minggang Xiao, Rongfeng Huang, Juan Wang

“…In the past few decades, the mechanisms of plant adaptation to salt stress have been described, especially relying on ionic homeostasis, reactive oxygen species (ROS) scavenging, and phytohormone signaling. …”
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Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance by Triin Eglit, Tarvo Rajasalu, Margus Lember

“…Insulin resistance was estimated using the homeostasis model assessment (HOMA-IR). The crude and weighted prevalence of metabolic syndrome was 27.9% and 25.9%, respectively. …”
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LncRNAs: New Players in Apoptosis Control by Marianna Nicoletta Rossi, Fabrizio Antonangeli

“…Apoptosis is a well regulated type of programmed cell death necessary for correct organ development and tissue homeostasis. Indeed, cancer cells often show an inhibition of the apoptotic pathways and it is now emerging that overexpression or downregulation of different lncRNAs in specific types of tumors sensitize cancer cells to apoptotic stimuli. …”
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The Challenges and Opportunities in the Clinical Application of Noncoding RNAs: The Road Map for miRNAs and piRNAs in Cancer Diagnostics and Prognostics by Preethi Krishnan, Sambasivarao Damaraju

“…We now understand that coding and noncoding RNA machinery work in concert to maintain overall homeostasis. Based on their length, noncoding RNAs are broadly classified into two groups—long (>200 nt) and small noncoding RNAs (<200 nt). …”
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Coordination of transporter, cargo, and membrane properties during non-vesicular lipid transport by Alena Ballekova, Andrea Eisenreichova, Bartosz Różycki, Evzen Boura, Jana Humpolickova

“…Abstract Homeostasis of cellular membranes is maintained by fine-tuning their lipid composition. …”
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Underscoring long-term host-microbiome interactions in a physiologically relevant gingival tissue model by M. Adelfio, G. E. Callen, A. R. Diaz, B. J. Paster, X. He, H. Hasturk, C. E. Ghezzi

“…This in vitro platform can maintain tissue homeostasis at the interface of the periodontal niche, thus, offering opportunities to identify predictive disease biomarkers and to develop intervention strategies to promote oral and overall health.…”
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The Role and Function of Regulatory T Cells in Toxoplasma gondii-Induced Adverse Pregnancy Outcomes by Xuyang Gao, Yue Zhong, Yifan Liu, Runmin Ding, Jinling Chen

“…Tregs, a special subpopulation of T cells, function as a vital regulator in maintaining immune homeostasis. Tregs exert a critical effect on forming and maintaining maternal-fetal tolerance and promoting fetal development during the pregnancy period. …”
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