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281
The diversity and applications of microbial iron metabolism and iron-containing proteins
Published 2025-02-01“…This collection reflects research that will advance the understanding of hemoproteins, iron-sulfur cluster proteins and other iron-containing proteins, proteins involved in homeostasis of iron/heme and their regulation, or ecological impacts of iron/heme on interacting hosts and microbial communities.…”
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282
Elsevier's Integrated Neuroscience /
Published 2007Table of Contents: “…Cells of the nervous system -- Electrical signaling by nerve cells -- Synaptic transmission -- Sensory receptors -- General organization of the nervous system -- Development of the nervous system -- Tissues supporting the nervous system -- Imaging the nervous system -- Somatosensory system -- Auditory system -- Vestibular system -- Visual system -- Chemical senses -- Motor neurons and motor units -- Basal ganglia -- Cerebellum -- Control of eye movements -- Homeostasis, motivation, and emotion -- Consciousness and cognition -- Formation, maintenance, and plasticity of neuronal connections -- Case studies -- Case study answers.…”
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283
N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models
Published 2018-01-01“…The present study aimed to evaluate the effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), such as docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids, on BA homeostasis and toxicity in human cell models. The effects of EPA and/or DHA on the expression of genes involved in the maintenance of BA homeostasis were analyzed in human hepatoma (HepG2) and colon carcinoma (Caco-2) cells, as well as in primary culture of human intestinal (InEpC) and renal (RPTEC) cells. …”
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284
Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities
Published 2018-01-01“…Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactivating antigen-presenting cells. …”
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285
Usp7 contributes to the tail regeneration of planarians via Islet/Wnt1 axis
Published 2025-01-01“…Abstract Background Regeneration plays a key role in energy recycling and homeostasis maintenance. Planarians, as ideal model animals for studying regeneration, stem cell proliferation, and apoptosis, have the strong regenerative abilities. …”
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286
4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
Published 2023-07-01“…Plasma membrane (PM) redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction. …”
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287
Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin
Published 2016-01-01“…Taken together, this work identifies SPA as a novel potential pharmacological agent able to control insulin secretion and glucose homeostasis.…”
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288
Mechanisms and environmental factors shaping the ecosystem of brain macrophages
Published 2025-01-01“…These cells play crucial roles in maintaining brain homeostasis and immune surveillance. Microglia and BAMs are phenotypically and epigenetically distinct and exhibit highly specialized functions tailored to their environmental niches. …”
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289
Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages
Published 2014-01-01“…Macrophages play a very important role in host defense and in iron homeostasis by engulfing senescent red blood cells and recycling iron. …”
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290
Gut microbiota-derived metabolites and chronic inflammatory diseases
Published 2025-01-01“…A deeper understanding of these mechanisms may open the way for novel therapeutic strategies aimed at restoring immune homeostasis and mitigating the global burden of chronic inflammatory diseases.…”
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291
Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats
Published 2025-01-01“…These data strongly suggest that rotenone disrupts metabolic homeostasis, leading to obesity and hyperinsulinemia. …”
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292
Bisphenol S impairs oocyte quality by inducing gut microbiota dysbiosis
Published 2025-01-01“…More importantly, we found that alginate oligosaccharide reshapes the gut microbiota to improve gut homeostasis, thereby preventing the deleterious effects of BPS on the gut and oocytes. …”
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293
Interaction between Dietary Vitamin D3 and Vitamin K3 in Gilthead Seabream Larvae (Sparus aurata) in Relation to Growth and Expression of Bone Development-Related Genes
Published 2023-01-01“…The results of the present study have shown the interaction between vitamin D3 supplementation and vitamin K3 supplementation in larval performance and gene expression related to bone development and calcium homeostasis, denoting the significance of a correct balance between both vitamins in larval diets.…”
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294
Hypercholesterolemia and 3-Hydroxy 3-Methylglutaryl Coenzyme A Reductase Regulation during Ageing
Published 2009-01-01“…In addition some pharmacological interventions to control proper HMGR regulation and, in turn, cholesterol homeostasis maintenance will be introduced.…”
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295
Biologiczne podstawy emocji. Rola stresu w regulacji procesu dojrzewania
Published 2008-12-01“…Stress is state of disturbed homeostasis, which generates a spectrum of adaptive physiological reactions in an organism, which promote individual’s survival or survival of a species. …”
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296
Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation
Published 2010-01-01“…The peroxisome proliferator-activated receptors (PPARs) are central regulators of fat metabolism, energy homeostasis, proliferation, and inflammation. The three PPAR subtypes, PPAR𝛼, 𝛽/𝛿, and 𝛾 activate overlapping but also very different target gene programs. …”
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297
Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents
Published 2021-01-01“…However, insulin-like growth factor binding protein (IGFBP) also plays an important role in glucose homeostasis, although the IGF-independent role of IGFBP-3 in the glucose intolerance state is poorly understood. …”
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298
Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion
Published 2019-01-01“…Low cerebral blood flow (CBF) during CCH leads to disturbances in the homeostasis of hemodynamics and energy metabolism, which in turn results in oxidative stress, astroglia overactivation, and synaptic protein downregulation. …”
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299
A conceptual mechanistic model of amino acid fluxes in the small intestine, taking the example of pig
Published 2025-02-01“…The pools were connected by fluxes, representing the main fates of AA, such as saturable transport of luminal AA or homeostasis of free or protein-bound AA in intestinal tissue. …”
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300
Advancements and Challenges in Immune Protection Strategies for Islet Transplantation
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