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281
Wnt/β-catenin and notch signaling pathways in cardiovascular disease: Mechanisms and therapeutics approaches
Published 2025-01-01“…In the adult cardiovascular system, these pathways continue to maintain tissue homeostasis and arrange adaptive responses to various physiological and pathological stimuli. …”
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282
Activated receptors for peroxisomic proliferators. Its role in the atherosclerosis, obesity and high blood pressure.
Published 2004-08-01“…PPAR receptors regulate the expressions of a great variety of genes that codify the proteins that are implied in the lipid metabolism, the energetic homeostasis, the cellular differentiation and the formation of tumours. …”
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283
Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Metabolism
Published 1995-01-01“…In addition, numerous unknowns surround the intricacies of bodily zinc homeostasis. Part two of this five-part review presents current views on the normal intestinal absorption, intracellular and extracellular metabolism, transport, excretion and homeostasis of zinc in the human body. …”
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284
Mechanistic insights into connexin-mediated neuroglia crosstalk in neurodegenerative diseases
Published 2025-02-01“…This review explores mechanistic insights of Cxs-mediated intercellular communication in the progression of neurodegenerative diseases and discusses the therapeutic potential of targeting Cxs to restore cellular homeostasis.…”
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285
Intestinal Host-Microbe Interactions under Physiological and Pathological Conditions
Published 2010-01-01“…The close interaction between host-symbiotic microbiota at the mucosal level poses important challenges since microbial breaches through the gut barrier can result in the breakdown of gut homeostasis. In this paper, hosts-integrated components that help to preserve intestinal homeostasis including barrier and immune function are discussed. …”
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286
The role of the NOTCH1 signaling pathway in the maintenance of mesenchymal stem cell stemness and chondrocyte differentiation and its potential in the treatment of osteoarthritis
Published 2025-01-01“…Additionally, the effects of NOTCH1 on chondrocyte homeostasis and apoptosis were evaluated by adding the EZH2 inhibitor GSK126 and the endoplasmic reticulum stress inducer tunicamycin. …”
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287
Escherichia coli stress response systems and their reaction to terahertz radiation
Published 2017-02-01“…The obtained data indicate that exposure to nonthermal terahertz radiation induces E. сoli gene networks of oxidative stress and copper ion homeostasis, but does not activate those responding to antibiotics, protonophores, or superoxide anions. …”
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288
The Impact of Incretin-Based Medications on Lipid Metabolism
Published 2021-01-01“…In the current review, how these antidiabetic medications can regulate lipid homeostasis and the possible cellular pathways involved are discussed, incorporating related clinical evidence about incretin effects on lipid homeostasis.…”
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289
Bioenergetic adaptations of small intestinal epithelial cells reduce cell differentiation enhancing intestinal permeability in obese mice
Published 2025-02-01“…However, diet-induced obesity (DIO) may impair mitochondrial activity of IEC and consequently, intestinal homeostasis. The aim of the project was to determine whether DIO alters the mitochondrial function of IEC, and what are the consequences on intestinal homeostasis. …”
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290
Biomolecular condensates: Formation mechanisms, biological functions, and therapeutic targets
Published 2023-04-01Get full text
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291
Coupling of alternative splicing and alternative polyadenylation
Published 2024-12-01Get full text
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292
Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions
Published 2024-12-01“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. …”
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293
Chemogenetic engagement of different GPCR signaling pathways segregates the orexigenic activity from the control of whole-body glucose metabolism by AGRP neurons
Published 2025-01-01“…Then we elicited chemogenetic activation of AGRP neurons in these mice during the postprandial state to determine the impact on feeding and glucose homeostasis. Results: Activation of AGRP neurons via hM3q and rM3s promoted hyperphagia. …”
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294
Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats
Published 2025-01-01“…This study investigates the relationship among Nef, glutamate homeostasis, and cocaine in the nucleus accumbens (NAc), a critical brain region associated with drug motivation and reward. …”
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295
Marrow Adipose Tissue: Its Origin, Function, and Regulation in Bone Remodeling and Regeneration
Published 2018-01-01“…Marrow adipose tissue (MAT) is a unique fat depot in the bone marrow and exhibits close relationship with hematopoiesis and bone homeostasis. MAT is distinct from peripheral adipose tissue in respect of its heterogeneous origin, site-specific distribution, and complex and perplexing function. …”
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296
The Role of Eosinophils in Liver DiseaseSummary
Published 2025-01-01“…Nevertheless, new research has shown that eosinophils are diverse and essential for immune regulation and tissue homeostasis. Their functional plasticity has been observed in patients with inflammatory diseases, cancer, infections, and other disorders. …”
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297
Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders
Published 2011-01-01“…At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. …”
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298
Adipose Tissue-Derived Extracellular Vesicles: A Promising Biomarker and Therapeutic Strategy for Metabolic Disorders
Published 2023-01-01“…Various cells in adipose tissue communicate with each other to maintain metabolic homeostasis. Extracellular vesicles (EVs) are recognized as novel medium for remote intercellular communication by transferring various bioactive molecules from parental cells to distant target cells. …”
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299
Trypanosoma cruzi Infection and Host Lipid Metabolism
Published 2014-01-01“…This review sheds light on the potential impact of T. cruzi infection on the status of host lipid homeostasis.…”
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300
Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases
Published 2025-02-01“…Emerging findings underscore the intricate interplay between calcium homeostasis and mitophagy, a selective type of autophagy for mitochondria elimination. …”
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