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Mesenchymal stem cells enchanced by salidroside to inhibit ferroptosis and improve premature ovarian insufficiency via Keap1/Nrf2/GPX4 signaling
Published 2025-12-01Subjects: Get full text
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Inter-organ metabolic interaction networks in non-alcoholic fatty liver disease
Published 2025-01-01Subjects: Get full text
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Adaptive potential of winter rye cultivars developed at VIR in the context of their grain protein content in the environments of Leningrad province
Published 2019-06-01Subjects: Get full text
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Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
Published 2025-02-01“…Thus, our study reveals a regulatory mechanism of p53 homeostasis and activity and, more broadly, defines a paradigm for dynamic arginine methylation in controlling important biological functions.…”
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268
ERBB4 selectively amplifies TGF-β pro-metastatic responses
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269
Mechanical Activation of cPLA2 Impedes Fatty Acid β‐Oxidation in Vein Grafts
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270
Counterintuitive DNA destabilization by monovalent salt at high concentrations due to overcharging
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Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula
Published 2016-01-01“…Sleep is governed by homeostasis and the circadian clock. Clock genes play an important role in the generation and maintenance of circadian rhythms but are also involved in regulating sleep homeostasis. …”
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273
Gender-Specific Cytokine Pathways, Targets, and Biomarkers for the Switch from Health to Adenoma and Colorectal Cancer
Published 2011-01-01“…Our results show that the interferon (IFN)γ production pathway for immune response homeostasis is specific to men whilst the interleukin- (IL-) 6 production pathway for immune response homeostasis is specific to women. …”
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274
Current Perspective About the Effect of a Ketogenic Diet on Oxidative Stress – a Review
Published 2024-03-01“…The shift in metabolism occurring in ketosis can affect the reactive oxygen species (ROS)-producing pathways and influence the expression of enzymes involved in redox homeostasis. Therefore, this review summarizes and discusses existing knowledge about KD and ROS homeostasis. …”
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275
Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease
Published 2015-01-01“…In eukaryotic cells, perturbation of protein folding homeostasis in the endoplasmic reticulum (ER) causes accumulation of unfolded and misfolded proteins in the ER lumen, which activates intracellular signaling pathways termed the unfolded protein response (UPR). …”
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276
Zinc Transporters, Mechanisms of Action and Therapeutic Utility: Implications for Type 2 Diabetes Mellitus
Published 2012-01-01“…Cellular homeostasis requires mechanisms that tightly control the uptake, storage, and distribution of zinc. …”
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277
Mitochondria as a Therapeutic Target: Focusing on Traumatic Brain Injury
Published 2025-01-01“…Mitochondria are organelles of eukaryotic cells delimited by two membranes and cristae that consume oxygen to produce adenosine triphosphate (ATP), and are involved in the synthesis of vital metabolites, calcium homeostasis, and cell death mechanisms. Strikingly, normal mitochondria function as an integration center between multiple conditions that determine neural cell homeostasis, whereas lesions that lead to mitochondrial dysfunction can desynchronize cellular functions, thus contributing to the pathophysiology of traumatic brain injury (TBI). …”
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2-Cys Peroxiredoxins: Emerging Hubs Determining Redox Dependency of Mammalian Signaling Networks
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Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis
Published 2025-01-01“…We found an imbalance in mitochondrial homeostasis and ferroptosis-induced impairment of osteogenic capacity in SIONFH. …”
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GATA2 participates in protection against hypoxia-induced pulmonary vascular remodeling.
Published 2024-01-01“…The vascular endothelium is vital for cardio-pulmonary homeostasis and, thus, plays a crucial role in preventing life-threatening lung diseases. …”
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