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221
Biomolecular condensates: Formation mechanisms, biological functions, and therapeutic targets
Published 2023-04-01Get full text
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222
Coupling of alternative splicing and alternative polyadenylation
Published 2024-12-01Get full text
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223
Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions
Published 2024-12-01“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. …”
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224
Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats
Published 2025-01-01“…This study investigates the relationship among Nef, glutamate homeostasis, and cocaine in the nucleus accumbens (NAc), a critical brain region associated with drug motivation and reward. …”
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225
Marrow Adipose Tissue: Its Origin, Function, and Regulation in Bone Remodeling and Regeneration
Published 2018-01-01“…Marrow adipose tissue (MAT) is a unique fat depot in the bone marrow and exhibits close relationship with hematopoiesis and bone homeostasis. MAT is distinct from peripheral adipose tissue in respect of its heterogeneous origin, site-specific distribution, and complex and perplexing function. …”
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226
Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders
Published 2011-01-01“…At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. …”
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227
Adipose Tissue-Derived Extracellular Vesicles: A Promising Biomarker and Therapeutic Strategy for Metabolic Disorders
Published 2023-01-01“…Various cells in adipose tissue communicate with each other to maintain metabolic homeostasis. Extracellular vesicles (EVs) are recognized as novel medium for remote intercellular communication by transferring various bioactive molecules from parental cells to distant target cells. …”
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228
Trypanosoma cruzi Infection and Host Lipid Metabolism
Published 2014-01-01“…This review sheds light on the potential impact of T. cruzi infection on the status of host lipid homeostasis.…”
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229
Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases
Published 2025-02-01“…Emerging findings underscore the intricate interplay between calcium homeostasis and mitophagy, a selective type of autophagy for mitochondria elimination. …”
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230
Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases
Published 2019-01-01“…This review aims at summarizing the novel insights into macrophage heterogeneity, plasticity, and functions in skeletal muscle homeostasis, regeneration, and disease.…”
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231
Biophysical aspects of mechanotransduction in cells and their physiological/biological implications in vocal fold vibration: a narrative review
Published 2025-01-01“…Given the high mobility of vocal folds, it is hypothesized that mechanotransduction significantly contributes to their tissue homeostasis. Recent studies have identified mechanosensitive proteins in vocal fold epithelia, supporting this hypothesis. …”
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232
Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components
Published 2017-01-01“…In this review, we discuss the role of different intestinal stem cell niche components and dissect the interaction between dynamic matrix factors and regulatory signalling during intestinal stem cell homeostasis.…”
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233
Adaptation Strategies for Hemp in Alkaline Salt Environments: Fertilizer Management for Nutrient Uptake and Optimizing Growth
Published 2025-01-01“…This optimal combination maintains the K<sup>+</sup>/Na<sup>+</sup> ratio in leaves above 1.2 and regulated Ca<sup>2+</sup>/Mg<sup>2+</sup> homeostasis, maintaining a ratio of 2.8–3.2, indicating improved salt tolerance. …”
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234
Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction
Published 2025-01-01“…The intestinal barrier plays a crucial role in maintaining homeostasis in the body. When the intestinal mucosa is damaged, the tight junctions between intestinal cells are disrupted, and the intestinal flora becomes imbalanced, a variety of diseases can arise. …”
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235
NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18)
Published 2025-01-01“…Inflammation is a critical response of the immune system to infection or injury, serving to repair and restore tissue homeostasis. While acute inflammation generally protects against harmful stimuli, prolonged and chronic inflammation have detrimental effects and disrupts tissue homeostasis. …”
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236
Brown fat thermogenesis and branched-chain amino acids in metabolic disease
Published 2024-02-01“…Recent advances in metabolomics, advanced imaging techniques, and genetic analyses over the past decade have enabled newfound insights into the mechanism of BCAA metabolic dysregulation across a variety of peripheral tissues and its impact on metabolic disease, suggesting a key role for brown adipose tissue (BAT) in determining BCAA metabolic homeostasis. Previous investigations into BAT have emphasized fatty acids and glucose as substrates for BAT thermogenesis. …”
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237
Introduction to Anatomy and Physiology for Healthcare Students /
Published 2018Table of Contents: “…Atoms, elements and compounds -- Cells, tissues and organs -- Homeostasis -- Skeletal system -- Blood -- Immunity -- Cardiovascular system -- Blood pressure -- Respiratory system -- Renal system -- Digestive system -- Nervous system -- Endocrine system -- Reproductive system.…”
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238
Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids
Published 2025-01-01“…However, the impact of immune cell-modulating IBD drugs on epithelial homeostasis and repair is poorly understood. It is likely that these drugs will have distinct mechanisms of action (MOA) in intestinal epithelium relevant for homeostasis that will vary among patients. …”
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239
Research Progress in Short-Chain Fatty Acid Modulation of the Gut-Bone Axis in Bone Metabolism
Published 2025-01-01“…Furthermore, SCFAs play positive roles in maintaining bone homeostasis and contribute to the alleviation of inflammatory bone loss. …”
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240
Neuroimmune axis: Linking environmental factors to pancreatic β-cell dysfunction in Diabetes
Published 2025-02-01“…In addition, it is well-established that there is a fine-tuned communication between the immune and neuroendocrine tissues in maintaining endocrine pancreas homeostasis.Various psycho-social, physico-chemical and lifestyle environmental factors have been associated with diabetes risk. …”
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