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  3. 223

    Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

    Published 2024-12-01
    “…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. …”
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  4. 224

    Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats by Jessalyn Pla-Tenorio, Bethzaly Velazquez-Perez, Yainira Mendez-Borrero, Myrella L. Cruz, Marian T. Sepulveda-Orengo, Richard J. Noel

    Published 2025-01-01
    “…This study investigates the relationship among Nef, glutamate homeostasis, and cocaine in the nucleus accumbens (NAc), a critical brain region associated with drug motivation and reward. …”
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  5. 225

    Marrow Adipose Tissue: Its Origin, Function, and Regulation in Bone Remodeling and Regeneration by Qiwen Li, Yunshu Wu, Ning Kang

    Published 2018-01-01
    “…Marrow adipose tissue (MAT) is a unique fat depot in the bone marrow and exhibits close relationship with hematopoiesis and bone homeostasis. MAT is distinct from peripheral adipose tissue in respect of its heterogeneous origin, site-specific distribution, and complex and perplexing function. …”
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  6. 226

    Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders by Clara Camaschella, Laura Silvestri

    Published 2011-01-01
    “…At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. …”
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  7. 227

    Adipose Tissue-Derived Extracellular Vesicles: A Promising Biomarker and Therapeutic Strategy for Metabolic Disorders by Wenhui Liu, Tianyan Liu, Qingyu Zhao, Junqiu Ma, Jiajia Jiang, Hui Shi

    Published 2023-01-01
    “…Various cells in adipose tissue communicate with each other to maintain metabolic homeostasis. Extracellular vesicles (EVs) are recognized as novel medium for remote intercellular communication by transferring various bioactive molecules from parental cells to distant target cells. …”
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  8. 228

    Trypanosoma cruzi Infection and Host Lipid Metabolism by Qianqian Miao, Momar Ndao

    Published 2014-01-01
    “…This review sheds light on the potential impact of T. cruzi infection on the status of host lipid homeostasis.…”
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  9. 229

    Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases by Fivos Borbolis, Christina Ploumi, Konstantinos Palikaras

    Published 2025-02-01
    “…Emerging findings underscore the intricate interplay between calcium homeostasis and mitophagy, a selective type of autophagy for mitochondria elimination. …”
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  10. 230

    Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases by Junio Dort, Paul Fabre, Thomas Molina, Nicolas A. Dumont

    Published 2019-01-01
    “…This review aims at summarizing the novel insights into macrophage heterogeneity, plasticity, and functions in skeletal muscle homeostasis, regeneration, and disease.…”
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  11. 231

    Biophysical aspects of mechanotransduction in cells and their physiological/biological implications in vocal fold vibration: a narrative review by Junseo Cha, Susan L. Thibeault

    Published 2025-01-01
    “…Given the high mobility of vocal folds, it is hypothesized that mechanotransduction significantly contributes to their tissue homeostasis. Recent studies have identified mechanosensitive proteins in vocal fold epithelia, supporting this hypothesis. …”
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  12. 232

    Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components by Laween Meran, Anna Baulies, Vivian S. W. Li

    Published 2017-01-01
    “…In this review, we discuss the role of different intestinal stem cell niche components and dissect the interaction between dynamic matrix factors and regulatory signalling during intestinal stem cell homeostasis.…”
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  13. 233

    Adaptation Strategies for Hemp in Alkaline Salt Environments: Fertilizer Management for Nutrient Uptake and Optimizing Growth by Yunshu Ye, Haoyu Wang, Panpan Zhang, Yuhong Zhang

    Published 2025-01-01
    “…This optimal combination maintains the K<sup>+</sup>/Na<sup>+</sup> ratio in leaves above 1.2 and regulated Ca<sup>2+</sup>/Mg<sup>2+</sup> homeostasis, maintaining a ratio of 2.8–3.2, indicating improved salt tolerance. …”
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  14. 234

    Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction by LI Yi, REN Xinxin, WANG Qin, HE Xiaoyun

    Published 2025-01-01
    “…The intestinal barrier plays a crucial role in maintaining homeostasis in the body. When the intestinal mucosa is damaged, the tight junctions between intestinal cells are disrupted, and the intestinal flora becomes imbalanced, a variety of diseases can arise. …”
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  15. 235

    NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18) by Yael Schlichter Kadosh, Subramani Muthuraman, Ariel Kushmaro, Rajendran Saravana Kumar, Jacob Gopas

    Published 2025-01-01
    “…Inflammation is a critical response of the immune system to infection or injury, serving to repair and restore tissue homeostasis. While acute inflammation generally protects against harmful stimuli, prolonged and chronic inflammation have detrimental effects and disrupts tissue homeostasis. …”
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  16. 236

    Brown fat thermogenesis and branched-chain amino acids in metabolic disease by Zachary Brown, Takeshi Yoneshiro

    Published 2024-02-01
    “…Recent advances in metabolomics, advanced imaging techniques, and genetic analyses over the past decade have enabled newfound insights into the mechanism of BCAA metabolic dysregulation across a variety of peripheral tissues and its impact on metabolic disease, suggesting a key role for brown adipose tissue (BAT) in determining BCAA metabolic homeostasis. Previous investigations into BAT have emphasized fatty acids and glucose as substrates for BAT thermogenesis. …”
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  17. 237

    Introduction to Anatomy and Physiology for Healthcare Students / by Sturgeon, David

    Published 2018
    Table of Contents: “…Atoms, elements and compounds -- Cells, tissues and organs -- Homeostasis -- Skeletal system -- Blood -- Immunity -- Cardiovascular system -- Blood pressure -- Respiratory system -- Renal system -- Digestive system -- Nervous system -- Endocrine system -- Reproductive system.…”
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  18. 238

    Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids by Arun Sridhar, Ingunn Bakke, Shreya Gopalakrishnan, Nimo Mukhtar Mohamud Osoble, Emilie Prytz Hammarqvist, Henrik P. Sahlin Pettersen, Arne Kristian Sandvik, Ann Elisabet Østvik, Marianne Doré Hansen, Torunn Bruland

    Published 2025-01-01
    “…However, the impact of immune cell-modulating IBD drugs on epithelial homeostasis and repair is poorly understood. It is likely that these drugs will have distinct mechanisms of action (MOA) in intestinal epithelium relevant for homeostasis that will vary among patients. …”
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  19. 239

    Research Progress in Short-Chain Fatty Acid Modulation of the Gut-Bone Axis in Bone Metabolism by ZHANG Xuan, YANG Xue, LI Xinke, MENG Lu, WANG Jiaqi, ZHENG Nan

    Published 2025-01-01
    “…Furthermore, SCFAs play positive roles in maintaining bone homeostasis and contribute to the alleviation of inflammatory bone loss. …”
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  20. 240

    Neuroimmune axis: Linking environmental factors to pancreatic β-cell dysfunction in Diabetes by Luz Andreone

    Published 2025-02-01
    “…In addition, it is well-established that there is a fine-tuned communication between the immune and neuroendocrine tissues in maintaining endocrine pancreas homeostasis.Various psycho-social, physico-chemical and lifestyle environmental factors have been associated with diabetes risk. …”
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