Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer by Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller, Ádám Domonkos Tárnoki, Dávid László Tárnoki, Martina Mészáros, András Bikov, András Bikov, Péter Horváth

“…The aim of this study was to assess the potential role of circulating S1P and anti-ceramide antibody as biomarkers in non-small cell lung cancer (NSCLC).MethodsWe recruited 66 subjects (34 controls and 32 patients with NSCLC). Patient history and clinical variables were taken from all participants. …”
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Construction and validation of a prediction model for fall risk in hospitalized older adults with osteoporosis by Li Sun, Hai-Yan Gu, Guan-Hua Xu, Jia-Wei Jiang, Ting-Ting Wang, Dan-Dan Li, Bai-Hong Cui

“…Model performance was evaluated using the area under the receiver operator characteristic curve (AUC), Hosmer-Lemeshow goodness-of-fit test, and clinical decision curve analysis, assessing the discrimination ability, calibration, and clinical utility of the model.ResultsBased on logistic regression analysis, we identified several significant fall risk factors for older adults with osteoporosis: gender of the study participant, bone mineral density, serum calcium levels, history of falls, fear of falling, use of walking aids, and impaired balance. …”
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Preferences for and drivers of adult vaccination clinic site selection: A cross-sectional study in 30 provinces in China by Yuxi Liu, Yanlin Cao, Yugang Li, Siyuan Liu, Yunshao Xu, Weizhong Yang, Luzhao Feng

“…Our findings reveal that adults’ site preferences for vaccination are influenced by gender, age, income, and vaccination history. Participants showed a strong preference for locations that offer convenience, efficiency, transparent pricing, and a comfortable environment. …”
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Parental Sociodemographic Characteristics and Bruxism’s Risk Factors Among Children: Saudi Arabian Evaluation by Almabadi ES, Felemban D, Alekhmimi RK, Aynusah MA, Alsharif A, Althagafi N, Kassim S

“…Sociodemographic characteristics, the child’s medical history, sleep patterns and parents’ awareness of bruxism and its symptoms were investigated. …”
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Insight into the current practice of ototoxicity monitoring during cisplatin therapy by N. M. Santucci, B. Garber, R. Ivory, M. A. Kuhn, M. Stephen, D. Aizenberg

“…Results Three hundred seventy-nine patients met study criteria, of which 104 (27.4%) had a prior history of hearing loss. Prior to treatment, 196 (51.7%) patients were counseled regarding the ototoxic nature of cisplatin and 92 (24.3%) patients had a pretreatment audiogram. …”
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The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review by Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G

“…Traditional Chinese medicine (TCM), with a history rooted in centuries of clinical practice, plays a crucial role in enhancing immune responses, alleviating cancer-related symptoms, and reducing the risks of infections and complications in cancer patients.Methodology: This review systematically examines the current literature on TCM-based formulations in cancer immunotherapy. …”
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A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by Estrogen/Gestagen Therapy by Yoshihide Inayama, Koji Yamanoi, Baku Nakakita, Shimpei Shitanaka, Jumpei Ogura, Tsutomu Ohara, Mie Sakai, Haruka Suzuki, Koji Yasumoto, Ichiro Kishimoto, Yusuke Sagae, Yoshimi Kitawaki, Koh Suginami

“…A 22-year-old nulligravid woman with a history of bilateral hemorrhagic corpus luteum and subsequent ovarian torsion presented with acute abdominal pain. …”
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Cardiac Tamponade Caused by Cutibacterium acnes: An Updated and Comprehensive Review of the Literature by Ghina Fakhri, Christelle Tayeh, Ghassan Dbaibo, Omar El Sedawy, Nour Abdul Halim, Fadi Bitar, Mariam Arabi

“…In our institution, a 20-year-old man with history of atrial septal defect presented with chest pain radiating to the back along with symptoms of upper respiratory tract infection including headaches and myalgia. …”
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Predicting high sensitivity C-reactive protein levels and their associations in a large population using decision tree and linear regression by Somayeh Ghiasi Hafezi, Toktam Sahranavard, Alireza Kooshki, Marzieh Hosseini, Amin Mansoori, Elham Amir Fakhrian, Helia Rezaeifard, Mark Ghamsary, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…The proposed DT model appears to be able to predict the hs-CRP levels based on anxiety score, depression scores, fasting blood glucose, systolic blood pressure, and history of cardiovascular diseases.…”
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EVALUATING THE IMPACT OF MASS TOURISM ON THE HOSPITALITY INDUSTRY AND TOURISM DESTINATION DEVELOPMENT OF CROSS RIVER STATE, NIGERIA by Nnana Okoi OFEM, Chinasa UTTAH, Ndem Samuel ETIM, Queen Olubukola AYENI, Josephat Owan EMEKA, Agnes Awoli EWURU, Maxwell-Borjor Achuk EBA, Eja Iwara EJA, Jeremiah ABANBESHIE, Daniel Daniel JAMES, Ayuk Awunghe ACHU, Michael Takim OTU, Fidelis Ngaji AKWAJI, Etta Oyen ETTA

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Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020 by Tomas Amare Abraha, Gebremedhin Kinfe Gebremariam, Berhane Teklay Asfaha, Tensay Kahsay Weldegebreal, Desta Hailu Aregawi

“…Rural residence [AOR = 2.16, 95%CI (1.069, 4.38)], three and below antenatal care follow-up visits [AOR = 6.6, 95%CI (3.345,13.10)], bad obstetric history [AOR = 2.8, 95%CI (1.044,7.691)], and having less than or equal 11 g/dl hemoglobin level at admission were [AOR = 3.7,95%Cl (1.93,6.914)] found as predictors of adverse birth outcome in this study. …”
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Evaluating ChatGPT, Gemini and other Large Language Models (LLMs) in orthopaedic diagnostics: A prospective clinical study by Stefano Pagano, Luigi Strumolo, Katrin Michalk, Julia Schiegl, Loreto C. Pulido, Jan Reinhard, Guenther Maderbacher, Tobias Renkawitz, Marie Schuster

“…A total of 115 patients completed a paper-based questionnaire covering symptoms, medical history, and demographic information. The diagnostic performance of five different LLMs—including four versions of ChatGPT, two of Gemini, Llama, Gemma 2, and Mistral-Nemo—was analysed. …”
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Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing by Feng T, Shan G, Hu Y, He H, Pei G, Zhou R, Ou Q

“…A nomogram was constructed using multivariate logistic regression after Least Absolute Shrinkage and Selection Operator (LASSO) regression identified six predictors: waist circumference, age, ODI, diabetes status, family history of hypertension, and apnea. Model performance was evaluated using area under the curve (AUC), calibration plots, and decision curve analysis (DCA).Results: The model, developed in a cohort of 680 participants and validated in 401 participants, achieved an AUC of 0.775 (95% CI: 0.730– 0.820) in validation set. …”
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Hospitalisation from seasonal influenza among persons with type 1 diabetes: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Björn Eliasson, Hanne Krage Carlsen, Lena Svensson, Magnus Gisslén, Elin Allansson Kjölhede, Oliver Martyn

“…Within the T1D cohort, individuals hospitalised due to influenza were older, were more often smokers, had lower glomerular filtration rate and more often had a previous history of ischaemic heart disease and stroke.Conclusions To our knowledge, this is the first large study to highlight that persons with T1D have a threefold higher risk of hospitalisation due to seasonal influenza compared with matched controls from the general population. …”
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BST1047+1156: A (Failing) Ultradiffuse Tidal Dwarf in the Leo I Group by J. Christopher Mihos, Patrick R. Durrell, Aaron E. Watkins, Stacy S. McGaugh, John Feldmeier

“…While our imaging reaches approximately two magnitudes below the tip of the red giant branch at the Leo I distance of 11 Mpc, we find no evidence for an old red giant sequence that would signal an extended star formation history for the object. Instead, we clearly detect the red and blue helium-burning sequences of its stellar populations, as well as the fainter blue main sequence, all indicative of a recent burst of star formation having taken place over the past 50–250 Myr. …”
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Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex by Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy

“…There was a significant link between medical history and the outcome of this investigation (p. value < 0.05 and OR > 1) All of the risk factors for CKD were hypertension, acute kidney disease, HCV infection, hyperlipidemia, renal stones, anemia, and cardiovascular disease. alcohol consumption had a significant difference with CKD (p. value =0.004). …”
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Rapid diversification of St-genome-sharing species in wheat grasses (Triticeae: Poaceae) accompanied by diversifying selection of chloroplast genes by Li-Na Sha, Ning Chen, Shi-Yong Chen, Yue Zhang, Yi-Ran Cheng, Dan-Dan Wu, Yi Wang, Hou-Yang Kang, Hai-Qin Zhang, Xiao Ma, Yong-Hong Zhou, Xing Fan

“…In combination with plastome data, further investigations using other genomes, such as the nuclear genome, are urgently needed to enhance our understanding of the evolutionary history of the St-genome-sharing taxa, especially to determine whether adaptive changes in the nuclear genome are accelerated as well because plastome represents the maternal inheritation in angiosperms.…”
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First report of non-marine ostracods (Crustacea, Ostracoda) from the Dahlak Archipelago (Eritrea), with the description of two new species by Giampaolo Rossetti, Ilaria Mazzini, Giorgio Chiozzi, Luca Vecchioni, Federico Marrone

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Status and risk factors for depression, anxiety, and insomnia symptoms among adolescents in the post-pandemic era by Xing-Jie Yang, Li-Bin Zhang, Lei-Lei Wang, Hu Deng, Yu-Long Li, Rong-Jia Zhao, Jia-Yan Xu, Yu-Chun Yang, Shuang-Jiang Zhou

“…Logistic regression analysis indicated heightened rates of depression, anxiety, and insomnia symptoms among rural adolescents, females, those aged 16–18 years, individuals with a history of COVID-19, those with a long COVID-19 illness, and those with increased screen time (all P < 0.001). …”
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A rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants by Bashar Kamal Ali Douden, Yazan Mohammad Abdullah Abufara, Mahmood Fayez Ali Aldrabeeh, Naela Ramadan Mohammad Tell, Ismail Abudaya

“…Case presentation A 39-year-old male from Hebron, Palestine, presented with a 7-month history of postural instability, imbalanced gait, and progressive deterioration of his lower extremities. …”
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