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1881
Can CT Image Reconstruction Parameters Impact the Predictive Value of Radiomics Features in Grading Pancreatic Neuroendocrine Neoplasms?
Published 2025-01-01“…However, variations in reconstruction parameters can impact the predictive value of radiomics. 127 patients with histopathologically confirmed PanNENs underwent CT scans with filtered back projection (B20f) and iterative (I26f) reconstruction kernels. 3190 radiomic features were extracted from tumors and pancreatic volumes. …”
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1882
Tumor organoids in cancer medicine: from model systems to natural compound screening
Published 2025-12-01“…These self-assembled 3D cell clusters closely replicate the histopathological, genetic, and phenotypic characteristics of primary tissues, making them invaluable tools in cancer research and drug screening.Objective This review addresses the challenges in developing in vitro models that accurately reflect tumor heterogeneity and explores the application of tumor organoids in cancer research, with a specific focus on the screening of natural products for antitumor therapies.Methods This review synthesizes information from major databases, including Chemical Abstracts, Medicinal and Aromatic Plants Abstracts, ScienceDirect, Google Scholar, Scopus, PubMed and Springer Link. …”
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1883
Undetermined Ruptured Low‐Grade Appendiceal Mucinous Neoplasm Following High‐Energy Blunt Abdominal Trauma Requiring Emergency Laparotomy
Published 2025-01-01“…LAMN was suspected, and the appendix was completely resected, with cytoreductive surgery carefully performed. Histopathological examination confirmed the diagnosis of LAMN. …”
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1884
Exploring brain perfusion in dogs with meningoencephalitis of unknown origin: A promising role for arterial spin labeling imaging
Published 2025-01-01“…Future studies with histopathological confirmation are needed to better characterize the benefits of ASL in the different subtypes of non‐infectious encephalomyelitis in dogs.…”
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1885
Murine model for chronic rhinosinusitis: an interventional study
Published 2023-04-01“…Treatment with mometasone significantly reversed the histopathological changes observed in CRS mice. Conclusion and significance This murine model induced substantial local eosinophilic inflammation within sinonasal mucosa, that was reversible with mometasone. …”
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1886
Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and D...
Published 2014-01-01“…This investigation intended to evaluate the association between FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 gene and protein expression levels in tumor tissue with clinical and histopathological neoplastic parameters of cancer dissemination. …”
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1887
Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China
Published 2014-01-01“…The clinical, laboratory, and renal histopathological data of patients with renal TMA from 2000 to 2012 in our institute were collected and reviewed. …”
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1888
Is <i>Punica granatum</i> Efficient Against Sepsis? A Comparative Study of Amifostine Versus Pomegranate
Published 2025-01-01“…Biochemical analysis demonstrated that TBARS and TNF-α levels significantly decreased in both the PGPE and amifostine treatment groups compared to the CLP group, while TT levels showed notable improvement. Histopathological evaluation revealed reduced MMP-2 and MMP-9 immunopositivity in the PGPE250 and PGPE500 groups. …”
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1889
Achalasia—An Autoimmune Inflammatory Disease: A Cross-Sectional Study
Published 2015-01-01“…Herpes simplex virus-1 (HSV-1) infection was determined by in situ hybridization, RT-PCR, and immunohistochemistry. Histopathological analysis showed capillaritis (51%), plexitis (23%), nerve hypertrophy (16%), venulitis (7%), and fibrosis (3%). …”
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1890
Undifferentiated Embryonal Sarcoma of the Liver Involving All Major Hepatic Veins Treated by Left Extended Trisectionectomy
Published 2022-01-01“…She was discharged on the 7th postoperative day without complications. The histopathological and immunohistochemical analysis demonstrated an undifferentiated embryonal sarcoma of the liver. …”
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1891
MSC-derived exosome ameliorates pulmonary fibrosis by modulating NOD 1/NLRP3-mediated epithelial-mesenchymal transition and inflammation
Published 2025-01-01“…Classic molecular biology approaches such as RT-qPCR, Western blot, immunofluorescence, and ELISA were used to examine molecular pathways. Histopathological examination was performed using HE and Masson staining. …”
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1892
Risk Factors for Chronic Mastitis in Morocco and Egypt
Published 2013-01-01“…Both groups were identified from histopathologically diagnosed patients from 2008 to 2011, frequency-matched on age. …”
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1893
The myometrial transcriptome changes in mares with endometrosis
Published 2025-01-01“…Myometria were collected from mares in the mid-luteal phase of the estrous cycle with endometrium categories I, IIA, IIB, and III (∑n = 23), according to Kenney and Doig´s histopathological classification. Myometrial RNA was isolated and subjected to RNA-seq analysis to identify differentially expressed transcriptionally active regions (deTARs) and their contribution to signaling pathways (KEGG database) and biological processes (GO terms). …”
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1894
IgG4-Related Kidney Disease: Report of a Case Presenting as a Renal Mass
Published 2017-01-01“…The patient underwent radical right nephroureterectomy and histopathologic examination revealed features proving IgG4-RKD. …”
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1895
Integration of Metabolomics and Transcriptomics to Reveal the Antitumor Mechanism of <i>Dendrobium officinale</i> Polysaccharide-Based Nanocarriers in Enhancing Photodynamic Immuno...
Published 2025-01-01“…<b>Methods</b>: The effects of TPA-3BCP-loaded cholesteryl hemisuccinate–<i>Dendrobium officinale</i> polysaccharide nanoparticles (DOP@3BCP NPs) and their potential molecular mechanism of action in a tumor-bearing mouse model of CRC were investigated using non-targeted metabolomics and transcriptomics. Meanwhile, a histopathological analysis (H&E staining, Ki67 staining, and TUNEL assay) and a qRT-PCR analysis revealed the antitumor effects of DOP@3BCP NPs with and without light activation. …”
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1896
Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples
Published 2024-12-01“…This approach facilitates histopathological and biochemical evaluation in the same sample and is safe owing to the inactivation of infectivity. …”
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1897
Effects of Whole-Body 50-Hz Magnetic Field Exposure on Mouse Leydig Cells
Published 2004-01-01“…No MF exposurerelated histopathological alterations were found in testicles, epididymes, adrenals, prostates, and pituitary glands. …”
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1898
Practical Consequences Resulting from the Analysis of a 21-Multigene Array in the Interdisciplinary Conference of a Breast Cancer Center
Published 2018-01-01“…Instead a thorough compilation and careful analysis of conventional parameters for therapeutic decision-making should take precedence, with special emphasis on histopathological and immunohistochemical results. In selected cases, however, a multigene assay can be a useful tool in the deliberation for or against a therapeutic pathway.…”
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1899
Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis
Published 2016-01-01“…Experimental autoimmune encephalomyelitis (EAE) is a mouse model that reproduces cardinal signs of clinical, histopathological, and immunological features found in Multiple Sclerosis (MS). …”
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1900
Chordoma Spontaneous Regression After COVID-19
Published 2024-12-01“…Tumor resection was performed, and both histopathological and immunohistochemistry confirmed diagnosis of chordoma with positive brachyury levels. …”
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