A Rare Case of Testicular Tuberculosis Mimicking as Testicular Malignancy by S. Rishabh, K. Krishnamoorthy, T. Joseph Pratheeban, E. Mathan, O. M. Rahman Shahul Hameed

“…With a strong suspicion of malignancy, the patient underwent bilateral high inguinal orchiectomy. Histopathological analysis of the excised tissue showed dense epithelioid granulomas with caseous necrosis, indicative of TB. …”
Get full text

The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…The results demonstrated that application of hAMC significantly ameliorated the disease severity and histopathological changes in EAE mice. The production of proinflammatory cytokines such as IFN-γ, TNF-α, IL-1β, and IL-17A in the spleen and CNS was dramatically inhibited. …”
Get full text

Adrenal Incidentalomas: Should We Operate on Small Tumors in the Era of Laparoscopy? by Michał Pędziwiatr, Michał Natkaniec, Mikhail Kisialeuski, Piotr Major, Maciej Matłok, Damian Kołodziej, Anna Zub-Pokrowiecka, Piotr Budzyński, Andrzej Budzyński

“…Operation parameters and histopathological results were analyzed. No differences in group characteristics, mean operation time, and estimated blood loss were noted. …”
Get full text

Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology by Francesca Caso, Benno Gesierich, Maya Henry, Manu Sidhu, Amanda LaMarre, Miranda Babiak, Bruce L. Miller, Gil D. Rabinovici, Eric J. Huang, Giuseppe Magnani, Massimo Filippi, Giancarlo Comi, William W. Seeley, Maria Luisa Gorno-Tempini

“…Three years later (11 years from first symptom), post-mortem histopathological evaluation revealed Pick's disease, with severe degeneration of left IFG, mid-insula, and precentral gyrus. …”
Get full text

Inhibition of Corneal Neovascularization by Topical and Subconjunctival Tigecycline by Sertan Goktas, Ender Erdogan, Rabia Sakarya, Yasar Sakarya, Mustafa Yılmaz, Muammer Ozcimen, Nejat Unlukal, Ismail Alpfidan, Fatih Tas, Erkan Erdogan, Abdulkadir Bukus, Ismail Senol Ivacık

“…Corneal sections were analyzed histopathologically. Results. The median percentages of corneal neovascularization in groups 1 and 3 were 48% (95% confidence interval (CI), 44.2–55.8%) and 33.5% (95% CI, 26.6–39.2%), respectively. …”
Get full text

PHARAOH: A collaborative crowdsourcing platform for phenotyping and regional analysis of histology by Kevin Faust, Min Li Chen, Parsa Babaei Zadeh, Dimitrios G. Oreopoulos, Alberto J. Leon, Ameesha Paliwal, Evelyn Rose Kamski-Hennekam, Marly Mikhail, Xianpi Duan, Xianzhao Duan, Mugeng Liu, Narges Ahangari, Raul Cotau, Vincent Francis Castillo, Nikfar Nikzad, Richard J. Sugden, Patrick Murphy, Safiyh S. Aljohani, Philippe Echelard, Susan J. Done, Kiran Jakate, Zaid Saeed Kamil, Yazeed Alwelaie, Mohammed J. Alyousef, Noor Said Alsafwani, Assem Saleh Alrumeh, Rola M. Saleeb, Maxime Richer, Lidiane Vieira Marins, George M. Yousef, Phedias Diamandis

“…Abstract Deep learning has proven capable of automating key aspects of histopathologic analysis. However, its context-specific nature and continued reliance on large expert-annotated training datasets hinders the development of a critical mass of applications to garner widespread adoption in clinical/research workflows. …”
Get full text

Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma by Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Takeshi Ishii

“…Knowledge of the atypical clinical course and a combination of histopathological examinations are necessary to accurately diagnose NF.…”
Get full text

Evaluation of Six Patients with Pulmonary Carcinosarcoma with a Literature Review by Sinem Nedime Sökücü, Celalettin Kocatürk, Nur Ürer, Yaşar Sönmezoğlu, Levent Dalar, Levent Karasulu, Sedat Altın, Mehmet Ali Bedirhan

“…The preoperative diagnosis of carcinosarcoma of the lung is difficult due to the composition of the different histopathological structures. Complete surgical resection is the treatment of choice for pulmonary carcinosarcoma, although further studies are needed.…”
Get full text

First Account of Primary Leiomyosarcoma of the Lesser Omentum since Establishment of c-Kit Mutations in Gastrointestinal Stromal Tumors by Fumito Saijo, Kaoru Sato, Tomoko Handa, Yoichi Narushima, Naoki Matsumura, Noriyuki Iwama, Fumie Nakayama, Hiromi Tokumura

“…A laparoscopic partial resection of the stomach was performed. Histopathological examination revealed the tumor to be a leiomyosarcoma arising from the lesser omentum that did not invade the stomach. …”
Get full text

The Effects of Trimetazidine and Sildenafil on Bilateral Cavernosal Nerve Injury Induced Oxidative Damage and Cavernosal Fibrosis in Rats by Dogan Atilgan, Bekir S. Parlaktas, Nihat Uluocak, Fikret Erdemir, Fatma Markoc, Oguzhan Saylan, Unal Erkorkmaz

“…Tissue superoxide dismutase (SOD), malondialdehyde (MDA), and protein carbonyl (PC) levels were determined biochemically and distribution of cavernosal fibrosis density among groups was performed histopathologically. Results. Tissue SOD levels in BCI group were significantly lower than the control group (P<0.05). …”
Get full text

Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Liter... by Nicolas Macagno, Stéphane Fuentes, Gonzague de Pinieux, André Maues de Paula, Sébastien Salas, Jean-Camille Mattéi, Charlotte Dupuis, Romain Appay, Alain Aurias, Henry Dufour, Dominique Figarella-Branger, Corinne Bouvier

“…After surgical resection, histopathological examination revealed a tumor harboring combined features of well-differentiated liposarcoma and low-grade osteosarcoma. …”
Get full text

Exertional Myopathy in a Juvenile Green Sea Turtle (Chelonia mydas) Entangled in a Large Mesh Gillnet by Brianne E. Phillips, Sarah A. Cannizzo, Matthew H. Godfrey, Brian A. Stacy, Craig A. Harms

“…Mild, multifocal, and acute myofiber necrosis was identified by histopathological examination. While histological changes in the examined muscle were modest, the acid-base, mineral, and electrolyte abnormalities were sufficiently severe to contribute to this animal’s mortality. …”
Get full text

Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats by Maria Rosana Ramirez, Debora Manuale, Juan Carlos Yori

“…Commercial kits were used to determine serum glucose concentration, lipid profile (cholesterol, HDL-cholesterol, triglycerides), and the two main aminotransferases glutamic-oxalacetic transaminase (GOT)/glutamate-pyruvate transaminase (GPT). A histopathological assay was performed on the heart, liver, and spleen tissues of animals. …”
Get full text

Everolimus-Eluting Biodegradable Abluminal Coating Stent versus Durable Conformal Coating Stent: Termination of the Inflammatory Response Associated with Neointimal Healing in a Po... by Masayuki Mori, Kenji Sakata, Junichiro Yokawa, Chiaki Nakanishi, Kota Murai, Hirofumi Okada, Masaya Shimojima, Shohei Yoshida, Kazuaki Yoshioka, Yoh Takuwa, Kenshi Hayashi, Masakazu Yamagishi, Masa-aki Kawashiri

“…Twelve Synergy™ and Promus PREMIER™ were implanted in 12 swine. Histopathological analysis of the stented segments was performed on the 2nd and 14th days after implantation. …”
Get full text

Choriocarcinoma Syndrome as an Initial Presentation of Testicular Cancer by Carlos Eduardo Salazar-Mejía, María Elena García-Gutiérrez, María Inés Contreras-Salcido, Carlos Javier Rodríguez-Álvarez, Blanca Otilia Wimer-Castillo, Jackeline Grace Lara-Campos, Edio Llerena-Hernández, José Luis González-Vela, David Hernández-Barajas

“…Imaging studies showed metastatic lung, bone, and retroperitoneal disease. β-hCG serum levels were 222,493.21 IU/L, AFP 1.56 ng/mL, and DHL 457 IU/L. Histopathological study after right radical orchiectomy showed a mixed germ-cell tumor. …”
Get full text

Insights into the Multidisciplinary Approach for Metastatic Acinic Cell Lung Carcinoma: The Pathologist’s Role in Romania Today by Dorela-Codruta Lazureanu, Amelia Burlea, Robert Barna, Daniela Cipu, Mihaela Pasca Fenesan, Ioan Icma, Marioara Cornianu

“…<b>Results</b>: Histopathological reports were consistent for lung ACC with regional lymph node involvement and remote metastases. …”
Get full text

Mesenteric desmoid tumor after laparoscopic resection of stage I endometrial cancer: A case report by Mamiko Kusaka, Tetsuo Maeda, Kazuhiro Kitajima, Homare Murakoshi, Takahiro Watanabe, Shigeki Yoshida, Yuka Sano, Noriko Osumi, Mieko Inagaki

“…The mesenteric tumor was resected, along with part of the jejunum and the greater omentum. Histopathological examination of the surgical specimens confirmed the diagnosis of DT. …”
Get full text

Understanding the role of nerves in head and neck cancers - a review by Krzysztof Rutkowski, Michał Gola, Michał Gola, Janusz Godlewski, Janusz Godlewski, Anna Starzyńska, Anna Starzyńska, Giulia Marvaso, Giulia Marvaso, Federico Mastroleo, Federico Mastroleo, Maria Giulia Vincini, Maria Giulia Vincini, Alice Porazzi, Mattia Zaffaroni, Barbara Alicja Jereczek-Fossa, Barbara Alicja Jereczek-Fossa

“…This review explores nerve-cancer interactions, including perineural invasion (PNI), cancer-related axonogenesis, neurogenesis, and nerve reprogramming, with an emphasis on their molecular mechanisms, mediators and clinical implications. PNI, an adverse histopathologic feature, has been widely investigated in HNCs. …”
Get full text

Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice by Hongxing Zhang, Chi Shang, Zhao Tian, Hatem K. Amin, Rami B. Kassab, Ahmed E. Abdel Moneim, Yingang Zhang

“…Remarkably, DADS was found to inhibit the inflammatory signaling, suppressed the developed oxidative damage, and protected the histopathological alterations in the inflamed paw tissue in response to carrageenan injection. …”
Get full text

CHROMOPHOBE HEPATOCELLULAR CARCINOMA: DIAGNOSTIC CHALLENGES by Sana Ben-Slama, Ines Mallek, Eya Ghorbeli, Mohamed Hajri, Taher Labidi, Hafedh Mestiri, Ahlem Lahmar, Dhouha Bacha

“…Accurate diagnosis necessitates thorough histopathological assessment and molecular testing. The identification of the alternative lengthening of telomeres phenotype may distinguish CHCC from conventional HCC and hold potential implications for targeted therapeutic approaches. …”
Get full text