Effect of Metformin and Sitagliptin on Doxorubicin-Induced Cardiotoxicity in Rats: Impact of Oxidative Stress, Inflammation, and Apoptosis by Mina Thabet Kelleni, Entesar Farghaly Amin, Aly Mohamed Abdelrahman

“…Results of our study revealed that pretreatment with metformin or sitagliptin produced significant (P<0.05) cardiac protection manifested by a significant decrease in serum levels of LDH and CK-MB enzymes and cardiac MDA and total nitrites and nitrates levels, a significant increase in cardiac SOD activity, and remarkable improvement in the histopathological features as well as a significant reduction in the immunohistochemical expression of COX-2, iNOS, and caspase-3 enzymes as compared to DOX group. …”
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Confluent and Reticulated Papillomatosis Successfully Treated with Topical Vitamin A Derivative by Manal Alsulami, Bader Alharbi, Yaser Alotaibi, Fadi Alghamdi, Adel Alsantali

“…The diagnosis was revised to CARP based on clinical and histopathological examination. Treatment with topical tretinoin 0.025% cream once daily was begun. …”
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New-Onset Lichen Planus Induced by the Pfizer COVID-19 Vaccine by Fadi A. Alghamdi, Shahad T. Khayyat, Mohammed M. Alshareef, Wala’a Felemban

“…Complete clinical, laboratory, and histopathological assessment of a patient was performed with ethical and privacy considerations. …”
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Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications by Serena Fragiotta, Solmaz Abdolrahimzadeh, Rosa Dolz-Marco, Yoichi Sakurada, Orly Gal-Or, Gianluca Scuderi

“…Hyperreflective foci (HRF) is a term coined to depict hyperreflective dots or roundish lesions within retinal layers visualized through optical coherence tomography (OCT). Histopathological correlates of HRF are not univocal, spacing from migrating retinal pigment epithelium cells, lipid-laden macrophages, microglial cells, and extravasated proteinaceous or lipid material. …”
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Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report by Rakesh Kumar Kodakkandla, Venkata Sreedatta Sarraju, Nagesh Ayalasomayajula

“…Intraoperative findings confirmed the rupture of right and non-coronary cusps from their annular attachment and the myxomatous nature of the aortic valve. Histopathological examination confirmed the myxomatous changes in the valve. …”
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Development of Two Types of Skin Cancer in a Patient with Systemic Sclerosis: a Case Report and Overview of the Literature by Firdevs Ulutaş, Erdem Çomut, Veli Çobankara

“…Systemic sclerosis (SSc) is an uncommon rheumatic disease in which the underlying main histopathologic feature is a thickening of the skin due to excessive accumulation of collagen in the extracellular tissue. …”
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Metachronous Liver Metastasis from Alpha-Fetoprotein-Producing Gastric Cancer Successfully Treated with Capecitabine/Oxaliplatin Combination Chemotherapy by Soichi Furukawa, Takashi Kobayashi, Saori Shiono, Shuta Nishinakagawa

“…As no remote metastases were detected, the patient underwent open total gastrectomy with lymphadenectomy and Roux-en-Y reconstruction. Histopathological examination revealed regional lymph node metastasis and the invasion of the muscularis propria by a moderately differentiated adenocarcinoma. …”
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Hepatitis C Virus, Cryoglobulinemia, and Kidney: Novel Evidence by Fabrizio Fabrizi

“…HCV is associated with a large spectrum of histopathological lesions in both native and transplanted kidneys, and it is increasingly recognized as an instigator of B cell lympho-proliferative disorders including mixed cryoglobulinemia. …”
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Investigations on Polymeric Nanoparticles for Ocular Delivery by Neeraj Mittal, Gurpreet Kaur

“…The confocal scanning laser microscopy (CSLM) studies also confirmed the ability of nanoparticles to penetrate into deeper layers of cornea. The histopathological studies revealed corneal biocompatibility of nanoparticles. …”
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Pyogenic granuloma causing midline diastema: A rare case report by Anjan Jana, Santanu Mukhopadhyay, Abu Faijal Karim

“…Following routine oral prophylaxis, the surgical procedure was performed, with the excised tissue sent for histopathological evaluation, confirming the diagnosis as pyogenic granuloma. …”
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Genetic Alterations in Presumptive Precursor Lesions of Breast Carcinomas by Michaela Aubele, Martin Werner, Heinz Höfler

“…However, little is currently known about genetic alterations in those premalignant lesions, and the chronology of genetic alterations and histopathological changes during carcinogenesis is mainly undiscovered. …”
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Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake by James A. Edwards

“…Subchronic OECD guideline studies with mice and rats receiving beadlet formulations of high purity synthetic zeaxanthin in the diet at dosages up to 1000 mg/kg body weight (bw)/day, and in dogs at over 400 mg/kg bw/day, produced no adverse effects or histopathological changes. In developmental toxicity studies, there was no evidence of fetal toxicity or teratogenicity in rats or rabbits at dosages up to 1000 or 400 mg/kg bw/day, respectively. …”
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Impact of Using Processed Urinary Bladder Submucosa and Hydrogel Fabricated from Tendon on Skin Healing Process in Rabbits by Majid A. Alkhilani, Omar Tariq Hammoodi, Hasanain Abduljabbar Emran, Wissam Abdullah Alhayani

“…Specimens from the injured skin were taken for the histopathological study on the postinjury day, 8th, 14th, 21st, and 24th. …”
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Aggressive Odontogenic myxoma: a case report by Yanelis Suárez Conde, Jordanis Viamontes Beltrán, René David Morales Basulto, Alicia María Hernández Suárez

“…A week after starting the medical treatment, the evolution was not favorable, so it was decided to perform computed tomography in which a large hypodense image was observed that involved the right mandibular branch. The histopathological study reported odontogenic myxoma. It was decided to perform tumor reduction and possible surgical treatment, however, this entity had an aggressive evolution and the patient dies less than two months after diagnosis. …”
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Immune complex induced arthritis in rats: role of lipid mediators on cell infiltration by F. A. C. Rocha, L. E. C. Andrade, S. Jancar

“…The animals were subjected to intraarticular injection of anti-bovine sertLm albumin (BSA) IgG antibodies followed by i.v. injection of BSA. Histopathological analysis of the synovial membranes disclosed infiltration of polymorphonuclear (PMN) cells and vascular congestion. …”
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Ocular adnexal lymphoma – A single-center observational study of survival outcomes by Karuvel Kannan Saraswathi, Pragya Saini, Radhakrishnan Santhi, Veerappan Muthukkaruppan, Ayyasamy Vanniarajan, Usha Kim

“…Purpose: This study aims to comprehensively characterize the clinical, demographic, and histopathological features of ocular adnexal lymphoma (OAL) and assess their impact on patients’ survival outcomes. …”
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Low Molecular Weight Fucoidan Can Inhibit the Fibrosis of Diabetic Kidneys by Regulating the Kidney Lipid Metabolism by Yan Wang, Yanlei Sun, Fengli Shao, Bo Zhang, Zhen Wang, Xinpeng Li

“…In this study, a diabetic kidney disease model was established by placing the test rats on a high-sugar/high-fat diet combined with streptozotocin induction. Histopathological examination (H&E, Masson, and PASM stain) showed pathological changes in the diabetic rat kidneys, in addition to fibrotic symptoms and collagen deposition. …”
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Laboratory Diagnosis of Invasive Aspergillosis: From Diagnosis to Prediction of Outcome by Richard C. Barton

“…Microscopic examination and culture of respiratory tract specimens have lacked sensitivity, and biopsy tissue for histopathological examination is rarely obtainable. Thus, for many years there has been a great interest in nonculture-based techniques such as the detection of galactomannan, β-D-glucan, and DNA by PCR-based methods. …”
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Toxicity of Brewery Effluents (Burukutu Effluent) to <i>Clarias gariepinus </i>and its Effect on some Target Organs by T.O. Ariyomo, A.M. Akinsorotan, E.N. Nwachukwu

“…Clarias gariepinus juveniles exposed to brewery effluent showed behavioural changes such as erratic swimming, loss of equilibrium, gasping for air, loss of reflex, discolouration, and it led to the death of some fish. The histopathological changes of the gills of fish exposed to brewery effluent for 96 hours at different concentrations showed swollen and shortened lamella, epithelial lifting, lamellar degeneration and loss, swollen lamellae with focal epithelial sloughing. …”
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Glomus Tumor in the Left Submandibular Region: A Rare Case Report and Literature Review by Huan Liu, Chengyao Zhu

“…In the absence of characteristic symptoms such as tenderness and cold sensitivity, the lesion was initially misdiagnosed as a pigmented nevus. Histopathological analysis subsequently confirmed the diagnosis as a glomus tumor. …”
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