Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure by Ikeotunye Royal Chinyere, Pierce Bradley, Joshua Uhlorn, Joshua Eason, Saffie Mohran, Giuliana G. Repetti, Sherry Daugherty, Jen Watson Koevary, Steven Goldman, Jordan J. Lancaster

“…At the study endpoint, all cohorts underwent echocardiographic, hemodynamic, electrophysiologic, and histopathologic assessments. Results. The epicardially placed tissue graft therapy improved (p<0.05) in vivo and ex vivo cardiac function compared to the untreated CHF cohort. …”
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Adverse outcome pathway-based assessment of pulmonary toxicity from the in vivo mixture of biocides dinotefuran and cetylpyridinium chloride by Yoon Cho, Mi-Kyung Song, Dong Im Kim, Min-Seok Kim, Kyuhong Lee

“…Various parameters, including clinical and histopathological indicators, changes in body weight and organ weight, inflammatory cell distribution, and inflammatory cytokine expression in the bronchoalveolar lavage fluid (BALF), were analyzed. …”
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Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway by Yingli Xuan, Ting-ting Ding, Xiao-lei Mao, Shiqing Pang, Ruibin He, Li Qin, Jiang zi Yuan

“…Besides, hematoxylin–eosin staining and periodic acid-Schiff staining were used to observe the pathological changes of kidney tissue; immunohistochemistry, western blot, and real-time quantitative PCR to assess the calmodulin-dependent protein kinase kinase beta (CaMKKβ)/AMPK signaling pathway activation.Results Liraglutide significantly reduced serum lipid loading, improved kidney function, and relieved kidney histopathological damage and glycogen deposition in the mouse model of obesity-related kidney disease induced by HFD. …”
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Alpha B-crystallin Ameliorates Imbalance of Redox Homeostasis, Inflammation and Apoptosis in an Acute Lung Injury Model with Rats by Seda KOCAK, İbrahim GUNER, Muhittin Onur YAMAN, Tugba EKIZ YILMAZ, Emine Elif GUZEL MEYDANLI, Nermin YELMEN, Gulderen SAHIN

“…However, alpha B-crystallin significantly reduced the lung tissue levels of oxidative, inflamatuvar, and apoptotic parameters in the plasma, lung tissues, and BAL fluid (p&lt;0.05 versus aortic IR). Histopathological results showed that alpha B-crystallin ameliorated the morphological changes related to lung injury (p&lt;0.001). …”
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Effect of Decellularized Amniotic Membrane on the Tendon–Bone Integration in Rotator Cuff Repair: A Comparative Rat Model Study by Jiangtao Wang, Chunbao Li, Jiating Zhang, Mingyang An, Gang Zhao, Samuel D. Stark, Yujie Liu

“…The assessment of specimens was conducted by micro‐CT analysis, histopathological evaluation, and biomechanical testing. …”
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Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress by Qing Liu, Yang Cao, Ruyi Hu, Libo Gu, Lirong Yang, Yu Liu, Weiwei Wang, Liang Xiao, Bugao Li

“…In this study, we conducted histological observations, biochemical measurements, transcriptomic analysis, and metabolomic analysis on liver tissue from a control group (22 ℃), an acute heat stress group (34 ℃, with samples taken at 0, 3, 6, 12, and 24 h), and a recovery group (sampled 24 h after recovery to 22 ℃). Histopathological analysis showed that liver damage worsened with the duration of heat stress. …”
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Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity? by Jules Weinhard, Justine Serre, Perrine Frère, Clovis Adam, Marie Camille Lafargue, David Buob, Cédric Rafat

“…Although liver injury subsided following the administration of N-acetyl cystein and silibinin, the patient subsequently developed KDIGO stage 3 acute kidney injury. Histopathological examination of the kidney displayed moderate tubular injury characterized by dilated tubular lumens and flattening of the tubular epithelium on optic microscopy. …”
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Acute and Subchronic Toxicity Assessment of Conventional Soxhlet Cymbopogon citratus Leaves Extracts in Sprague–Dawley Rats by Jacob Apibilla Ayembilla, Abdul Raouf Khalid, Sharif Buari Abubakari, Abdul Rashid Adams, Felix Abekah Botchway, Stephen Antwi, Phyllis Naa Yarley Otu, Michael Appiah, George Osei-Adjei, Kwame Owen Kottoh, Peace Ahiabenu-Williams, Olga Quasie

“…Analyses were conducted on the blood, urine, and serum samples of the rats. Histopathological examination of the liver, heart, kidney, spleen, and lungs was carried out at termination. …”
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Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…The specimens will undergo standard histopathological, microbiological, biochemical, and molecular tests. …”
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Evaluation of the Frequency of HLA-DQ2/DQ8 Genes Among Patients with Celiac Disease and Those on a Gluten-Free Diet by Marek K. Kowalski, Danuta Domżał-Magrowska, Ewa Małecka-Wojciesko

“…Methods: The study group included 50 patients, 13 men and 37 women, who had been diagnosed with celiac disease many years ago based on histopathological criteria and improvement of health condition after receiving a gluten-free diet. …”
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Spatiotemporal dynamics and prevention strategies of cervical cancer incidence in Addis Ababa, Ethiopia: an ecological study by Mathewos Assefa, Eva Johanna Kantelhardt, Teferi Gedif Fenta, Tariku Shimels

“…Objective This study analysed the spatial and temporal patterns of cervical cancer incidence in Addis Ababa from 2012 to 2021.Design An ecological study was conducted from 1 September to 30 November 2023 to examine the spatiotemporal trends of cervical cancer incidence.Setting The research was conducted in Addis Ababa, the capital city of Ethiopia.Participants Included were all patients with clinically and/or histopathologically confirmed diagnoses of cervical cancer.Data analysis The study employed advanced analytical tools including R programming, Quantum Geographic Information System V.3.36.0, GeoDa V.1.2.2 and System for Automated Geoscientific Analyses GIS V.9.3.2. …”
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Comparison of Platelet-Rich Plasma-Impregnated Suture Material with Low and High Platelet Concentration to Improve Colonic Anastomotic Wound Healing in Rats by Mehmet Akif Aydin, Eray Metin Guler, Ahu Senem Demiroz, Muhammet Fatih Aydin, Gulcan Saglam

“…Rats were sacrificed on the postoperative 7th day for analysis of colonic anastomosis region including macroscopic observation, measurement of anastomotic bursting pressure (ABP), and the hydroxyproline levels and histopathological findings in colon tissue samples. Results. …”
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Targeting Liver Biopsies For Optimal Biopsy Site In Diffused Liver Disease Using Real-Time Shear Wave Elastography: A Prospective, Single Center Study by Naushaba Malik, Shahbakht Aftab, Rida Noor, Noor Aftab, Rizwan, Rehan

“… Objective: The study aimed to pinpoint the precise site for liver biopsy using ultrasound and elastography guidance and to assess and compare the diagnostic accuracy of shear wave elastography (SWE) and transient elastography (TE) through histopathological correlation. Methodology: In this prospective single-centre study, the researchers divided the participants into two groups. …”
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A Novel Risk Score Model for the Differential Diagnosis of Type 2 Diabetic Nephropathy: A Multicenter Study by Yuetong Zhao, Lin Liu, Li Zuo, Xianghai Zhou, Song Wang, Hongwei Gao, Feng Yu, Xiaomei Zhang, Mi Wang, Ling Chen, Rui Zhang, Fang Zhang, Shuhong Bi, Qiong Bai, Jiaxiang Ding, Qinghua Yang, Sixu Xin, Sanbao Chai, Min Chen, Junqing Zhang

“…Patients were assigned to the DN group and NDKD group according to histopathological results. Seventy percent of patients from PKUFH were randomly assigned to the training group, and the remaining 30% were assigned to the internal validation group. …”
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Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006–2017) by Gábor Tóth, Nóra Szentmáry, Gábor László Sándor, Béla Csákány, Erika Maka, Jeannette Tóth, Zsuzsanna Antus, Milán Tamás Pluzsik, Achim Langenbucher, Zoltán Zsolt Nagy, Olga Lukáts

“…For each subject, clinicopathological data, including patient demographics, indications for enucleation, B-scan ultrasound reports, operative details, and histopathological analyses, were reviewed. Primary enucleation indications were classified into trauma, tumours, systemic diseases, surgical diseases, infections or inflammations, miscellaneous diseases, and unclassifiable groups. …”
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Effects of Titanium Dioxide Nanoparticles on Chick Embryo: Immunomodulatory, Hepatic and Biochemical Alterations by Md. Sadequl Islam, Md. Nurul Amin, Mst. Deloara Begum

“…In contrast, the eggs in the control group (Group C) were injected with 0.3 mL of saline solution. Histopathological changes were analysed using haematoxylin and eosin (H&E) staining, whereas amniotic fluid's biochemical properties were examined photometrically. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

“…The patient underwent left open adrenalectomy after preconditioning with α- and β-blockers and histopathological examination confirmed the diagnosis of pheochromocytoma (Ki-67<5%). …”
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Immunoexpression of P16 and Ki 67 in oral squamous cell carcinoma: Association with clinicopathological parameters. by Shadan Mohamad Omer, Payman Anwar Rashid

“…Lower lip was the most common site of the tumor followed by upper lip and tongue (42.0%, 26.0% and 18.0%, respectively). Histopathological findings of the tumor showed that (54.0%) of the patients had moderately differentiated squamous cell carcinoma. …”
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A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights by Ridwan S, Harsono AB, Suardi D, Kurniadi A, Mantilidewi KI, Hidayat YM

“…Ovarian cancer was suspected, and surgical staging with total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, frozen sectioning, and adhesiolysis was performed. Histopathological examination revealed a clear cell ovarian carcinoma.Discussion: Papillary thyroid carcinoma tends to be a locoregional metastasis, whereas distant metastases are rare. …”
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Analysis of the prognostic value of thyroglobulin antibody change trends during follow-up after 131I treatment in patients with differentiated thyroid carcinoma by Hua Ge, Wenxin Chen, Zhiyi Lin, Yuxuan Li, Shuting Chen

“…Patients were categorized into four subgroups based on changes in TgAb levels: the Negative Conversion Group (TgAb shifted from positive to sustained negativity), the Decrease Group (TgAb decreased by more than 50% but remained positive), the Stable Group (TgAb fluctuated by ≤ 50% throughout follow-up), and the Increase Group (TgAb increased by 50% or more). Clinical and histopathological data among the four groups, as well as disease persistence/recurrence status after 131I treatment, were compared.ResultsPre-treatment TgAb levels in the Negative Conversion Group were significantly lower than those in the other three groups (P&lt;0.001). …”
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