The Expression of Thymic AQP7 and Perilipin 1 (PLIN1) in Rats Fed a High-Fructose Diet is Modified by Voluntary Physical Activity by Jülide Tozkır, Nihayet Fırat, Ebru Göncü, Onur Ersoy, Pınar Tayfur, Orkide Palabıyık

“…At the end of 8 weeks, rats were euthanized under appropriate conditions, and tissue and blood samples were collected. Histological evaluation of the thymus was performed by hematoxylin-eosin staining. …”
Get full text

Liver morphometry and histopathology effects in Astyanax lacustris exposed to lambda-cyhalothrin pyrethroid insecticide by Tiago Venancio da Silva, André Luiz do Nascimento Silva, Karine Nathiele Nogueira Farias, Carla Leticia Gediel Rivero Wendt, Lucas de Oliveira Brasileiro, Edilaine Fogaça, Sabrina Fuzer Gonçalves, Brenda de Oliveira Martins, Maria Eduarda Corona Garcia, Lilian Franco-Belussi, Carlos Eurico S. Fernandes

“…These results show morphophysiological effects of LC at 10.30 µg/L in acute and chronic exposure represented by decreased glycogen storage, structural density, and volume of hepatocytes, in addition to a higher degree of histological changes.…”
Get full text

Neuroprotective Effect of Melatonin Loaded in Human Serum Albumin Nanoparticles Applied Subconjunctivally in a Retinal Degeneration Animal Model by Sofia Mickaela Martinez, Ayelen Inda, Maximiliano Nicolás Ríos, Carolina del Valle Bessone, Abril Bruera Bossio, Mario Eduardo Guido, José Domingo Luna Pinto, Daniel Alberto Allemandi, Daniela Alejandra Quinteros

“…Results: Np-HSA-Mel significantly preserved pupillary function and cell viability, demonstrating lower apoptosis compared to Mel solution and Np-HSA alone. Histologically, eyes treated with Np-HSA-Mel exhibited fewer structural alterations and greater cellular organisation. …”
Get full text

Malignancy Risk and Related Factors of Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance in Thyroid Fine Needle Aspiration by So-hyeon Hong, Hyejin Lee, Min-Sun Cho, Jee Eun Lee, Yeon-Ah Sung, Young Sun Hong

“…Radiological and clinical features were compared according to the second FNA results or histologically confirmed results from surgery. Repeat FNA was performed on 248 (36%) nodules, and 49 (7%) nodules underwent immediate surgery. …”
Get full text

Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13 by Kun-Chi Wu, Hui-I Yang, Yu-Hsun Chang, Raymond Yuh-Shyan Chiang, Dah-Ching Ding

“…Walking capacity (rotarod test), cartilage morphology, histological scores, and the expression of type II collagen, aggrecan, interleukin-1 beta, and matrix metalloproteinase 13 (MMP13) in the cartilage were evaluated. …”
Get full text

Intra-Articular Injection of Human Synovial Membrane-Derived Mesenchymal Stem Cells in Murine Collagen-Induced Arthritis: Assessment of Immunomodulatory Capacity In Vivo by Minglu Yan, Xin Liu, Qiujie Dang, He Huang, Fan Yang, Yang Li

“…The efficacy of SM-MSCs in CIA was evaluated clinically and histologically. Cytokine profile analyses were performed by real-time polymerase chain reaction and multiplex analyses. …”
Get full text

Naturally russeted and wound russeted skins of mango (cv. ‘Apple’) show no differences in anatomy, chemical composition or gene expression by Jannis Straube, Thomas O. Athoo, Viktoria Zeisler-Diehl, Kiran Suresh, Lukas Schreiber, Moritz Knoche

“…The objective was to establish histologies, gene expressions and chemical compositions of a natural periderm, a wound-induced periderm and of cuticles of an un-russeted skin. …”
Get full text

The problem of rare tumors in gynecology: a clinical case of benign retroperitoneal sclerosing pelvic pecoma in 49-year-old woman by V. I. Lanchinsky, Yu. V. Chushkov, A. B. Ponomarev, Yu. I. Osmanov, A. I. Ishchenko, N. V. Vorobev

“…Because of it’s rare occurrence the gynecologists often misinterpret available clinical data and the results of patient`s examination, diagnosing and treating the tumor as a myoma before having received the results of the histological examination. Our article describes a clinical case of a patient who had a preliminary diagnosis of uterine fibroids, and because of this fact the planned surgical treatment was carried out. …”
Get full text

Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer by Hava Izci, Gitte Zels, Anirudh Pabba, Marion Maetens, François Richard, Maxim De Schepper, Josephine Van Cauwenberge, Ha-Linh Nguyen, Kristien Borremans, Sophia Leduc, Karen Van Baelen, Sigrid Hatse, Tatjana Geukens, Amena Mahdami, Hans Wildiers, Patrick Neven, Wouter Van Den Bogaert, Giuseppe Floris, Christine Desmedt

“…Distant adipocyte size was quantified using digital pathology, and tumor infiltration was assessed histologically. Linear mixed quantile regression analyzed the associations between adipocyte size, fat depot type and major histological subtypes. …”
Get full text

Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy by Yiji Tu, Zenggan Chen, Feng Zhang, Zhenglin Di, Junhui Zhang, Li Cai

“…Diabetes in Sprague-Dawley rats was induced with streptozotocin (STZ) treatment, followed with neurological tests and histological examinations to assess the neuropathic symptoms of DPN. …”
Get full text

Dichotomitin promotes osteoblast differentiation and improves osteoporosis by inhibiting oxidative stress by Meichun Han, Weibin Du, Lei Zhang, Zhenwei Wang, Shengqiang Fang, Yang Zheng, Renfu Quan

“…Micro-CT evaluated the femoral, while histological examination assessed tibial tissues. Serum osteogenic biochemical markers were measured. …”
Get full text

A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A prelimin... by Mousa H. Daradka, Mays A. Malkawi, Zuhair Banni Ismail1, Hanan M. Hammouri, Mahmoud A. Abu-Abeeleh, Saba A. Rihani

“…Outcomes were evaluated through clinical assessments of lameness, post-operative complications, and histological analysis over 10, 20, 30, and 40 days. …”
Get full text

Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy by Madhusudan Roy, Jing-Tang Lin, Sohidul Mondal, Mei-Chun Lin, Chih-Yu Leu, Yen-Lin Huang, Chen-Yuan Dong, Pei-Jen Lou

“…However, the current clinical workflow only uses one histological section for PD-L1 scoring. The considerable under-sampling of a patient's tissue may lead to an inaccurate PD-L1 score, potentially affecting treatment outcomes. …”
Get full text

Type 2 Cytokine–Dependent Skin Barrier Regulation in Personalized 2-Dimensional and 3-Dimensional Skin Models of Atopic Dermatitis: A Pilot Study by Hila Emmert, Franziska Rademacher, Matthias Hübenthal, Regine Gläser, Hanne Norsgaard, Stephan Weidinger, Jürgen Harder

“…Whole-transcriptome analysis revealed that IL-4 and IL-13 acted similarly on these 3-dimensional skin models. Histologically, IL-13 alone and in combination with IL-4 increased epidermal spongiosis, a histological hallmark of AD skin. …”
Get full text

Pathobiology of Anaplastic Large Cell Lymphoma by Pier Paolo Piccaluga, Anna Gazzola, Claudia Mannu, Claudio Agostinelli, Francesco Bacci, Elena Sabattini, Carlo Sagramoso, Roberto Piva, Fernando Roncolato, Giorgio Inghirami, Stefano A. Pileri

“…The authors revise the concept of anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated with special reference to the cytological spectrum that is indeed characteristic of the tumor. …”
Get full text

Necrotizing Craniocervical Soft Tissue Infections: Clinical Experience and Personal Considerations by Stefania Gallo, Apostolos Karligkiotis, Riccardo Lenzi, Paolo Castelnuovo, Iacopo Dallan

“…Diagnosis of NCSTI has been confirmed histologically and surgically. Both patients were managed with very aggressive treatment (medical and surgical) and survived with minimal morbidity. …”
Get full text

A Rare Granular Cell Tumor with a Center Ulcer of the Rectum by Jeonghun Lee, Younghye Kim

“…We confirmed the diagnosis using histological and immunohistochemical examinations. In addition to our case report, we discuss the morphology, size, layer of invasion, and treatment of rectal granular cell tumors based on a literature review.…”
Get full text

Triple Synchronous Primary Neoplasms of the Cervix, Endometrium, and Ovary: A Rare Case Report and Summary of All the English PubMed-Indexed Literature by Ahmed Abu-Zaid, Mohannad Alsabban, Mohammed Abuzaid, Osama Alomar, Hany Salem, Ismail A. Al-Badawi

“…Herein, we report a single case of triple synchronous primary neoplasms of the cervix, endometrium, and left ovary with three distinct histological patterns that were not reported previously. …”
Get full text

Coexistent Congenital Diaphragmatic Hernia with Extrapulmonary Sequestration by Nao Kawamura, Samarjeet Bhandal

“…Bronchopulmonary foregut malformations are a heterogeneous but interrelated group of abnormalities that may contain more than one histologic feature. It is helpful to be familiar with the presentation and imaging features of bronchopulmonary foregut malformations presenting as a congenital mass or mass-like lesion, as imaging plays a central role in the evaluation of these lesions since, when symptomatic, clinical features are usually nonspecific. …”
Get full text

Chondroblastoma of the Knee Treated with Resection and Osteochondral Allograft Reconstruction by Judd Fitzgerald, Cory Broehm, David Chafey, Gehron Treme

“…Following appropriate imaging and core needle biopsy, the diagnosis was confirmed histologically. The patient then underwent intralesional curettage and osteochondral allograft reconstruction of the defect. …”
Get full text